Loss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria

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Loss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1048721415
P356DOI10.1186/1475-2875-13-354
P2888exact matchhttps://scigraph.springernature.com/pub.10.1186/1475-2875-13-354
P8608Fatcat IDrelease_nha5p47qsnfdnn3aptqfneh45u
P932PMC publication ID4164820
P698PubMed publication ID25192715
P5875ResearchGate publication ID265395260

P50authorCharles C. KimQ37383308
P2093author name stringAlyssa Baccarella
Brian W Huang
Mary F Fontana
P2860cites workCerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcomeQ21032453
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Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathwayQ47810239
Interleukin-10 modulates susceptibility in experimental cerebral malaria.Q47823424
MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.Q47833974
Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the hostQ47848814
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Plasma interleukin-10:Tumor necrosis factor (TNF)-alpha ratio is associated with TNF promoter variants and predicts malarial complicationsQ47872640
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Participation of lymphocyte subpopulations in the pathogenesis of experimental murine cerebral malariaQ48030499
Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central IndiaQ48031375
The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malariaQ48033393
Pathological role of Toll-like receptor signaling in cerebral malaria.Q48036899
Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infectionQ58845195
Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulationQ33618034
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Gamma delta T-cell function in pathogenesis of cerebral malaria in mice infected with Plasmodium berghei ANKA.Q34000104
Cytokines in the pathogenesis of and protection against malariaQ34174462
Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factorQ34292144
TLR11 activation of dendritic cells by a protozoan profilin-like protein.Q34414638
Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in miceQ34509018
The relevance of non-human primate and rodent malaria models for humansQ34585958
Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malariaQ34621573
Beta interferon suppresses the development of experimental cerebral malariaQ34740075
Association of cytokine and Toll-like receptor gene polymorphisms with severe malaria in three regions of CameroonQ35060420
Cytokines: accelerators and brakes in the pathogenesis of cerebral malariaQ35216393
Tumor necrosis factor ? in the pathogenesis of cerebral malariaQ35541025
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.Q35629356
Murine AIDS protects mice against experimental cerebral malaria: down-regulation by interleukin 10 of a T-helper type 1 CD4+ cell-mediated pathologyQ35682162
Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestrationQ35835353
The burden of the neurocognitive impairment associated with Plasmodium falciparum malaria in sub-saharan Africa.Q35872630
TLR9 and MyD88 are crucial for the development of protective immunity to malariaQ35936144
Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria.Q36477981
Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism.Q36655907
Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in IndiaQ36688537
Malaria: mechanisms of erythrocytic infection and pathological correlates of severe diseaseQ37014714
Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseasesQ37301031
Toll-like receptor 7 mediates early innate immune responses to malariaQ37336051
Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy conQ37523995
Neurological sequelae of cerebral malaria in childrenQ37601100
Cerebral malaria: why experimental murine models are required to understand the pathogenesis of diseaseQ37661151
Rethinking cerebral malaria pathologyQ37770899
Caspase-1 activation of interleukin-1β (IL-1β) and IL-18 is dispensable for induction of experimental cerebral malariaQ38284130
Induction of experimental cerebral malaria is independent of TLR2/4/9.Q39171649
Interferon-gamma is essential for the development of cerebral malariaQ39413194
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
toll-like receptorQ408004
cerebral malariaQ2822915
P304page(s)354
P577publication date2014-09-05
P1433published inMalaria JournalQ15749954
P1476titleLoss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria
P478volume13

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cites work (P2860)
Q40063063Blood-stage malaria of Plasmodium chabaudi induces differential Tlr expression in the liver of susceptible and vaccination-protected Balb/c mice
Q64266236Characterization of Plasmodium berghei Homologues of T-cell Immunomodulatory Protein as a New Potential Candidate for Protecting against Experimental Cerebral Malaria
Q56376508Genetic analysis of cerebral malaria in the mouse model infected with Plasmodium berghei
Q38937016Genetic predisposition of variants in TLR2 and its co-receptors to severe malaria in Odisha, India
Q63408452Human TLR8 Senses RNA From -Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells
Q40155612Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse model
Q35904007Mouse Models of Uncomplicated and Fatal Malaria.
Q41106752Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections.
Q60947070Parasite Recognition and Signaling Mechanisms in Innate Immune Responses to Malaria
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Q36281728Phagosomal Acidification Prevents Macrophage Inflammatory Cytokine Production to Malaria, and Dendritic Cells Are the Major Source at the Early Stages of Infection: IMPLICATION FOR MALARIA PROTECTIVE IMMUNITY DEVELOPMENT

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