ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin

scientific article published on August 3, 2010

ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.143248
P953full work available at URLhttp://www.jbc.org/content/285/42/32141.full.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20682781/pdf/?tool=EBI
http://intl.jbc.org/cgi/content/abstract/285/42/32141
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20682781/?tool=EBI
https://europepmc.org/articles/PMC2952215
https://europepmc.org/articles/PMC2952215?pdf=render
https://doi.org/10.1074/jbc.m110.143248
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https://syndication.highwire.org/content/doi/10.1074/jbc.M110.143248
P932PMC publication ID2952215
P698PubMed publication ID20682781

P50authorMitchell D KnutsonQ87774062
P2093author name stringNingning Zhao
Caroline A. Enns
Junwei Gao
P2860cites workHuman NRAMP2/DMT1, which mediates iron transport across endosomal membranes, is localized to late endosomes and lysosomes in HEp-2 cellsQ22253465
Structure-function analysis of a novel member of the LIV-1 subfamily of zinc transporters, ZIP14Q24337728
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidinQ24568204
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Cloning and characterization of a mammalian proton-coupled metal-ion transporterQ28245045
Transferrin receptor-independent uptake of differic transferrin by human hepatoma cells with antisense inhibition of receptor expressionQ28283005
Prediction of the Coding Sequences of Unidentified Human Genes. II. The Coding Sequences of 40 New Genes (KIAA0041-KIAA0080) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1Q28290913
Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liverQ28509001
Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cellsQ28509880
Identification of a Steap3 endosomal targeting motif essential for normal iron metabolismQ28512362
Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the ratQ28577977
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cellsQ28594532
Functional properties of transfected human DMT1 iron transporterQ30306462
Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase responseQ33784530
Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cellsQ34099118
Copper and iron transport across the placenta: regulation and interactionsQ34749080
Iron metabolism in the reticuloendothelial systemQ35086735
Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overloadQ35358811
Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.Q35796864
Liver iron transportQ36177913
Uptake and subcellular processing of 59Fe-125I-labelled transferrin by rat liverQ36481947
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studiesQ36731113
Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptakeQ36890133
Use of Nramp2-transfected Chinese hamster ovary cells and reticulocytes from mk/mk mice to study iron transport mechanismsQ37128047
Epitope tagging of endogenous proteins for genome-wide chromatin immunoprecipitation analysisQ37545581
The role of Hfe in transferrin-bound iron uptake by hepatocytesQ38292010
Recycling, degradation and sensitivity to the synergistic anion of transferrin in the receptor-independent route of iron uptake by human hepatoma (HuH-7) cellsQ38347408
Iron uptake and metabolism by hepatocytesQ39745710
The role of transferrin receptor 1 and 2 in transferrin-bound iron uptake in human hepatoma cellsQ39787443
The hereditary hemochromatosis protein, HFE, inhibits iron uptake via down-regulation of Zip14 in HepG2 cellsQ39975320
Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challengeQ40091097
Regulation of iron metabolism in HepG2 cells: a possible role for cytokines in the hepatic deposition of ironQ41522193
Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosisQ44904604
Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.Q52703198
Inhibition of uptake of transferrin-bound iron by human hepatoma cells by nontransferrin-bound iron.Q53736935
Effects of endotoxin on iron uptake by the hepatocyte.Q54724353
The G185R mutation disrupts function of the iron transporter Nramp2Q61186162
The effects of an antibody to the rat transferrin receptor and of rat serum albumin on the uptake of diferric transferrin by rat hepatocytesQ68501756
Mobilization of iron from endocytic vesicles. The effects of acidification and reductionQ68750412
Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis. Characterization by high performance liquid chromatography and nuclear magnetic resonance spectroscopyQ69057573
The mechanisms of iron uptake by fetal rat hepatocytes in cultureQ69618748
Internal iron exchange in the ratQ72203770
Ferric citrate uptake by cultured rat hepatocytes is inhibited in the presence of transferrinQ74523665
Functional role of DMT1 in transferrin-independent iron uptake by human hepatocyte and hepatocellular carcinoma cell, HLFQ83364195
P433issue42
P407language of work or nameEnglishQ1860
P921main subjectiron ion transmembrane transportQ14878803
Solute carrier family 39 member 14Q21135958
Solute carrier family 39 (zinc transporter), member 14Q21991042
P304page(s)32141-32150
P577publication date2010-08-03
P1433published inJournal of Biological ChemistryQ867727
P1476titleZRT/IRT-like protein 14 (ZIP14) promotes the cellular assimilation of iron from transferrin
ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin
P478volume285

Reverse relations

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