Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton

scientific article

Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.DEVCEL.2014.08.001
P932PMC publication ID4165403
P698PubMed publication ID25203209
P5875ResearchGate publication ID265517948

P50authorRaiko StephanQ41176966
David J. BarryQ42322776
Michael WayQ42572211
P2093author name stringTheresa E Higgins
Michael K Rosen
Morag C Martin
Sven Bogdan
Baoyu Chen
Anna Julia Squarr
Xing Judy Chen
P2860cites workInteraction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosisQ24302248
Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activityQ24314680
NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylationQ24314785
Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7AQ24338679
A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP familyQ24532768
Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinityQ24630138
Ena/VASP: towards resolving a pointed controversy at the barbed endQ24655039
Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongationQ24655828
The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesionsQ24675213
Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteinsQ24678535
A functional genomic analysis of cell morphology using RNA interferenceQ24794931
Multiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASPQ27643576
The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motilityQ39877031
Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusionsQ40621268
Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabledQ41870117
SCAR is a primary regulator of Arp2/3-dependent morphological events in DrosophilaQ42118144
The WAVE regulatory complex is inhibited.Q42152348
Gal4 in the Drosophila female germlineQ42465549
The serine/threonine kinase dPak is required for polarized assembly of F-actin bundles and apical-basal polarity in the Drosophila follicular epitheliumQ42510109
Abl-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesionQ42804141
Abi plays an opposing role to Abl in Drosophila axonogenesis and synaptogenesisQ43292867
A high resolution view of the fly actin cytoskeleton lacking a functional WAVE complexQ43696124
UNC-6/netrin and SLT-1/slit guidance cues orient axon outgrowth mediated by MIG-10/RIAM/lamellipodin.Q47068983
The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidanceQ47070926
Abi activates WASP to promote sensory organ developmentQ47071791
Characterization of a Novel Interaction Between Vasodilator-Stimulated Phosphoprotein and Abelson Interactor 1 in Human Platelets: A Concerted Computational and Experimental ApproachQ56993636
Lateral Membrane Waves Constitute a Universal Dynamic Pattern of Motile CellsQ57962222
Negative regulation of fibroblast motility by Ena/VASP proteinsQ73990271
Tes, a specific Mena interacting partner, breaks the rules for EVH1 bindingQ27649424
Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteinsQ28143848
Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinaseQ28188375
TES is a novel focal adhesion protein with a role in cell spreadingQ28207842
Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamicsQ28286512
RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesionQ28286523
PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteinsQ28301906
Peptide array X-linking (PAX): a new peptide-protein identification approachQ28483658
Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.Q28588154
A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complexQ28756055
Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motilityQ29618423
Physical mechanisms of signal integration by WASP family proteins.Q30156827
Hierarchical regulation of WASP/WAVE proteinsQ30157463
Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of EnabledQ30176335
enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.Q30193627
Ena/VASP proteins capture actin filament barbed endsQ30439841
Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesisQ30489574
Molecular mechanism of Ena/VASP-mediated actin-filament elongation.Q30498103
Abi is required for modulation and stability but not localization or activation of the SCAR/WAVE complexQ30557587
Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivoQ30557898
Site recognition and substrate screens for PKN family proteinsQ33958672
The MRL proteins: adapting cell adhesion, migration and growthQ34255351
VASP is a processive actin polymerase that requires monomeric actin for barbed end associationQ34412426
Drosophila pupal macrophages--a versatile tool for combined ex vivo and in vivo imaging of actin dynamics at high resolutionQ35030710
Expanding the morphogenetic repertoire: perspectives from the Drosophila eggQ35697490
Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodelingQ36117214
Molecular requirements for actin-based lamella formation in Drosophila S2 cellsQ36323318
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complexQ36450248
Drosophila egg chamber elongation: insights into how tissues and organs are shapedQ36459640
Diversity of polyproline recognition by EVH1 domainsQ37410050
Membrane and actin dynamics interplay at lamellipodia leading edgeQ38103643
Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila.Q38864765
Biochemical reconstitution of the WAVE regulatory complex.Q39015523
P4510describes a project that usesImageJQ1659584
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
Enabled Dmel_CG15112Q29809684
P1104number of pages16
P304page(s)569-584
P577publication date2014-09-01
P1433published inDevelopmental CellQ1524277
P1476titleEna/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton
P478volume30

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Q30407475WAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly

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