The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons

scientific article published on September 27, 2010

The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/1750-2187-5-17
P8608Fatcat IDrelease_5vx4uvdtljccze7c2hsfefy5ky
P953full work available at URLhttps://storage.googleapis.com/jnl-up-j-jms-files/journals/1/articles/72/submission/proof/72-1-516-1-10-20141204.pdf
http://www.jmolecularsignaling.com/content/5//17
http://www.jmolecularsignaling.com/content/5//17/abstract
http://www.jmolecularsignaling.com/content/pdf/1750-2187-5-17.pdf
https://doi.org/10.1186/1750-2187-5-17
https://europepmc.org/articles/PMC2954984
https://europepmc.org/articles/PMC2954984?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20868529/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20868529/pdf/?tool=EBI
P932PMC publication ID2954984
P698PubMed publication ID20868529
P5875ResearchGate publication ID46425067

P2093author name stringChien-Jen Chen
Linyi Chen
Hsin-Ling Hsu
Wan-Chen Lu
Hui-Chien Hsu
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Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathwayQ28569460
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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1Q29617416
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Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.Q40206763
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FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.Q40493379
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SH2-B Is a Positive Regulator of Nerve Growth Factor-mediated Activation of the Akt/Forkhead Pathway in PC12 CellsQ40625071
Oxidative stress-induced phospholipase C-gamma 1 activation enhances cell survivalQ40806452
Hydrogen peroxide in relation to proliferation and apoptosis in BHK-21 hamster fibroblastsQ41231026
Hydrogen Peroxide and the Proliferation of Bhk-21 CellsQ41278585
Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cellsQ42149374
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Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injuryQ42816281
Platelet-derived growth factor (PDGF) stimulates the association of SH2-Bbeta with PDGF receptor and phosphorylation of SH2-BbetaQ42827514
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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neuronsQ42918105
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Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury modelQ43213260
Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutaseQ43721242
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Adaptive concentrations of hydrogen peroxide suppress cell death by blocking the activation of SAPK/JNK pathwayQ43820085
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Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neuronsQ44072142
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ERK and MDM2 prey on FOXO3a.Q46774847
Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons.Q46931456
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
P304page(s)17
P577publication date2010-09-27
P1433published inJournal of Molecular SignalingQ15756114
P1476titleThe adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons
P478volume5

Reverse relations

cites work (P2860)
Q36602241Akt attenuates apoptotic death through phosphorylation of H2A under hydrogen peroxide-induced oxidative stress in PC12 cells and hippocampal neurons
Q31059372Interplay between cell migration and neurite outgrowth determines SH2B1β-enhanced neurite regeneration of differentiated PC12 cells
Q35048581New function of the adaptor protein SH2B1 in brain-derived neurotrophic factor-induced neurite outgrowth
Q36861068The C-ETS2-TFEB Axis Promotes Neuron Survival under Oxidative Stress by Regulating Lysosome Activity
Q38711030The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling

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