MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis.

scientific article

MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/0008-5472.CAN-11-1717
P932PMC publication ID5572464
P698PubMed publication ID21816906
P5875ResearchGate publication ID51547493

P50authorElzbieta GocekQ59158098
P2093author name stringGeorge P Studzinski
Chang-Gong Liu
Xiuping Liu
Xuening Wang
P2860cites workMicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progressionQ36498054
The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathwaysQ37420518
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Different susceptibilities to 1,25-dihydroxyvitamin D3-induced differentiation of AML cells carrying various mutations.Q39780907
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miR-181a regulates cap-dependent translation of p27(kip1) mRNA in myeloid cells.Q43127538
Inhibition of p38MAP kinase potentiates the JNK/SAPK pathway and AP-1 activity in monocytic but not in macrophage or granulocytic differentiation of HL60 cellsQ43635650
Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cellsQ44167310
Potentiation of 1-beta-D-arabinofuranosylcytosine cytotoxicity to HL-60 cells by 1,25-dihydroxyvitamin D3 correlates with reduced rate of maturation of DNA replication intermediatesQ44271562
AKT pathway is activated by 1, 25-dihydroxyvitamin D3 and participates in its anti-apoptotic effect and cell cycle control in differentiating HL60 cellsQ46945328
Potentiation by 1-alpha,25-dihydroxyvitamin D3 of cytotoxicity to HL-60 cells produced by cytarabine and hydroxyurea.Q50910177
A system for monocytic differentiation of leukemic cells HL 60 by a short exposure to 1,25-dihydroxycholecalciferolQ69838614
1 alpha,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cellsQ72025020
Antiapoptotic action of 1,25-dihydroxyvitamin D3 is associated with increased mitochondrial MCL-1 and RAF-1 proteins and reduced release of cytochrome cQ73661196
Jun N-terminal kinase pathway enhances signaling of monocytic differentiation of human leukemia cells induced by 1,25-dihydroxyvitamin D3Q73749865
MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysisQ79849727
Activation of intracellular signaling pathways is necessary for an increase in VDR expression and its nuclear translocationQ80120303
Acute myelogenous leukemiaQ83889468
The nuclear RNase III Drosha initiates microRNA processingQ24295234
Ribonuclease activity and RNA binding of recombinant human DicerQ24315047
Bim: a novel member of the Bcl-2 family that promotes apoptosisQ24532974
MicroRNA maturation: stepwise processing and subcellular localizationQ24534359
Fast and effective prediction of microRNA/target duplexesQ24537313
miRBase: microRNA sequences, targets and gene nomenclatureQ24538656
The microRNA.org resource: targets and expressionQ24650094
MicroRNAs regulate critical genes associated with multiple myeloma pathogenesisQ24654905
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elementsQ24656666
Regulation of the human p21(waf1/cip1) gene promoter via multiple binding sites for p53 and the vitamin D3 receptor.Q25256835
Nuclear export of microRNA precursorsQ27860686
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative BimQ28201672
Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemiaQ28282977
Natural selection on human microRNA binding sites inferred from SNP dataQ31071445
Activation of extracellular signal-regulated kinases (ERKs) defines the first phase of 1,25-dihydroxyvitamin D3-induced differentiation of HL60 cellsQ31910647
MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3Q33583422
Regulation of C/EBPbeta isoforms by MAPK pathways in HL60 cells induced to differentiate by 1,25-dihydroxyvitamin D3Q33622844
hKSR-2, a vitamin D-regulated gene, inhibits apoptosis in arabinocytosine-treated HL60 leukemia cellsQ33622860
The rationale for deltanoids in therapy for myeloid leukemia: role of KSR-MAPK-C/EBP pathway.Q33622877
Studies on the clinical efficacy and pharmacokinetics of low-dose arsenic trioxide in the treatment of relapsed acute promyelocytic leukemia: a comparison with conventional dosageQ34515285
MicroRNAs (miR)-221 and miR-222, both overexpressed in human thyroid papillary carcinomas, regulate p27Kip1 protein levels and cell cycleQ34698100
Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cellsQ34723871
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cellsQ34739775
Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancerQ34803786
Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamin D(3) and is required for optimal cell differentiationQ35958335
P4510describes a project that usesImageQuantQ112270642
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectmicroRNAQ310899
myeloid leukemiaQ11688946
apoptotic processQ14599311
leukemiaQ29496
P304page(s)6230-6239
P577publication date2011-08-04
P1433published inCancer ResearchQ326097
P1476titleMicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis
P478volume71

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