Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene

scientific article

Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI115479
P932PMC publication ID295693
P698PubMed publication ID1939651
P5875ResearchGate publication ID21215645

P2093author name stringNakayama Y
Rahman A
Weintraub BD
Cutler GB Jr
Notides AC
Radovick S
Ticknor CM
Wondisford FE
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Firefly luciferase gene: structure and expression in mammalian cellsQ29616519
Selective photochemical treatment of oestrogen receptor in a Xenopus liver extract destroys hormone binding and transcriptional activation but not DNA bindingQ33920245
Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placodeQ34314255
Thyroid hormones regulate levels of thyrotropin-releasing-hormone mRNA in the paraventricular nucleusQ34355847
Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin geneQ36924882
Administration of Gonadal Steroids to the Castrated Male Rat Prevents a Decrease in the Release of Gonadotropin-Releasing Hormone from the Incubated HypothalamusQ37035783
Gonadotropin-releasing hormone: role of pulsatile secretion in the regulation of reproductionQ39591986
The mammalian GnRH gene and its pivotal role in reproductionQ39667718
Gonadotropin-Releasing Hormone Gene Expression during the Rat Estrous Cycle: Effects of Pentobarbital and Ovarian Steroids*Q42465579
Steroid hormones modulate the release of immunoreactive gonadotropin-releasing hormone from cultured human placental cellsQ42479542
Differential effects of estrogen on luteinizing hormone-releasing hormone gene expression in slice explant cultures prepared from specific rat forebrain regionsQ42497335
A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene.Q43468787
Thyroid hormone inhibition of human thyrotropin beta-subunit gene expression is mediated by a cis-acting element located in the first exonQ43547120
The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elementsQ43679715
An estrogen-responsive element derived from the 5' flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cellsQ44741237
In situ hybridization histochemistry for messenger ribonucleic acid (mRNA) encoding gonadotropin-releasing hormone (GnRH): effect of estrogen on cellular levels of GnRH mRNA in female rat brainQ44961459
An upstream region of the rat luteinizing hormone beta gene binds estrogen receptor and confers estrogen responsivenessQ45140326
Relationship of nuclear estrogen receptor levels to induction of ovalbumin and conalbumin mRNA in chick oviductQ46072927
LHRH messenger RNA in neurons in the intact and castrate male rat forebrain, studied by in situ hybridizationQ48247941
Isolation and characterization of the human gonadotropin-releasing hormone gene in the hypothalamus and placentaQ48273519
Pituitary stalk portal blood collection in rhesus monkeys: evidence for pulsatile release of gonadotropin-releasing hormone (GnRH)Q48379748
Gene expression in hypothalamic neurons: luteinizing hormone releasing hormoneQ48405551
Absence of oestradiol concentration in cell nuclei of LHRH-immunoreactive neuronesQ48778335
Estradiol stimulates preoptic area-anterior hypothalamic proGnRH-GAP gene expression in ovariectomized ratsQ58853977
Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cellsQ67922355
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimerQ67927526
Evidence of estrogen receptors in normal human osteoblast-like cellsQ68424951
Regulation of pro-gonadotropin-releasing hormone gene expression by sex steroids in the brain of male and female ratsQ69263997
In situ hybridization for LHRH mRNA following estrogen treatmentQ69566493
Pulsatile gonadotropin secretion during the human menstrual cycle: evidence for altered frequency of gonadotropin-releasing hormone secretionQ70485177
Effect of castration and steroid replacement on immunoreactive gonadotropin-releasing hormone in hypothalamus and preoptic areaQ72129740
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectestrogenQ277954
P304page(s)1649-1655
P577publication date1991-11-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleEvidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene
P478volume88

Reverse relations

cites work (P2860)
Q48941969Cell-specific expression of the human gonadotropin-releasing hormone gene in transgenic animals.
Q41304765Circadian control of reproduction in the female rat.
Q30438057Classical estrogen receptor alpha signaling mediates negative and positive feedback on gonadotropin-releasing hormone neuron firing
Q31916260Cloning of the 11beta-hydroxysteroid dehydrogenase (11beta-HSD)-2 gene in the baboon: effects of estradiol on promoter activity of 11beta-HSD-1 and -2 in placental JEG-3 cells
Q35033720Differential distribution and response to experimental sexual maturation of two forms of brain gonadotropin-releasing hormone (GnRH) in the European eel, Anguilla anguilla.
Q30438114Differential regulation of gonadotropin-releasing hormone neuron activity and membrane properties by acutely applied estradiol: dependence on dose and estrogen receptor subtype
Q33631424Divergent Regulation of ER and Kiss Genes by 17β-Estradiol in Hypothalamic ARC Versus AVPV Models
Q48257122ERα and GnRH co-localize in the hypothalamic neurons of the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha).
Q35549236Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signaling
Q44867372Estrogen receptor-mediated repression of gonadotropin-releasing hormone (gnRH) promoter activity in transfected CHO-K1 cells
Q37188576Estrogen regulation of gene expression in GnRH neurons
Q35971696Estrogenic regulation of the GnRH neuron
Q40955141Evidence for oestrogen receptor alpha-immunoreactivity in gonadotrophin-releasing hormone-expressing neurones
Q34313647Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in asian and caucasian men.
Q48310052Expression of prepro-GnRH and GnRH receptor messengers in rainbow trout ovary depends on the stage of ovarian follicular development.
Q73759319GnRH receptors in human breast cancer and its contiguous not-involved breast tissue
Q37035786Gonadotropin-releasing hormone in the ovary
Q71798472Gonadotropin-releasing hormone neurons in the rhesus macaque are not immunoreactive for the estrogen receptor
Q37311383Gonadotropin-releasing hormone: regulation of the GnRH gene
Q41074266Hormonal and neurotransmitter regulation of GnRH gene expression and related reproductive behaviors.
Q43789118Identification of negative and positive estrogen response elements in human GnRH upstream promoter in the placental JEG-3 cells
Q43651286Immunohistochemical expression of gonadotropin releasing hormone receptor in human breast carcinoma
Q24803056In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene.
Q30885247Isolation and expression of tilapia (Oreochromis niloticus) serine 8-type GnRH coding and regulatory sequences
Q30439925Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol
Q36501031Kisspeptin increases GnRH mRNA expression and secretion in GnRH secreting neuronal cell lines
Q42378095Local production of neurostradiol affects gonadotropin-releasing hormone (GnRH) secretion at mid-gestation in Lagostomus maximus (Rodentia, Caviomorpha).
Q34254225Luteinizing hormone-releasing hormone (LHRH) neurons: mechanism of pulsatile LHRH release
Q41730823Modulating mechanisms of neuroendocrine cell activity: the LHRH pulse generator
Q50946495Modulation of preoptic regulatory factor-2 (porf-2) mRNAs by castration and hypophysectomy.
Q40918840Molecular biology of the regulation of hypothalamic hormones
Q42519146Molecular characterization of LH-beta and FSH-beta subunits and their regulation by estrogen in the goldfish pituitary
Q90248718Molecular cloning and characterization of a gonadotropin-releasing hormone 2 precursor cDNA in the catfish Heteropneustes fossilis: Expression profile and regulation by ovarian steroids
Q34328160Neuroendocrine-immune (NEI) circuitry from neuron-glial interactions to function: Focus on gender and HPA-HPG interactions on early programming of the NEI system
Q82863214Neuroendocrineimmunology (NEI) at the turn of the century: towards a molecular understanding of basic mechanisms and implications for reproductive physiopathology
Q26826892Neuroestrogen, rapid action of estradiol, and GnRH neurons
Q34167840Paracrine/autocrine control of female reproduction.
Q38766244Phoenixin Activates Immortalized GnRH and Kisspeptin Neurons Through the Novel Receptor GPR173.
Q59801000Phoenixin Expression Is Regulated by the Fatty Acids Palmitate, Docosahexaenoic Acid and Oleate, and the Endocrine Disrupting Chemical Bisphenol A in Immortalized Hypothalamic Neurons
Q47896013Regulation and expression of gonadotropin-releasing hormone in salmon embryo and gonad
Q40467476Regulation of gonadotropin-releasing hormone (GnRH) gene expression in hypothalamic neuronal cells
Q34611492Structure of the distal human gonadotropin releasing hormone (hGnrh) gene promoter and functional analysis in Gt1-7 neuronal cells
Q33210229Structure of the rat gonadotropin releasing hormone (rGnRH) gene promoter and functional analysis in hypothalamic cells
Q30426533The neurobiology of preovulatory and estradiol-induced gonadotropin-releasing hormone surges
Q40774315The salmon GnRH encoding gene in teleost fish.
Q28212618The transcription of the hGnRH-I and hGnRH-II genes in human neuronal cells is differentially regulated by estrogen
Q35074536Transgenic studies on the regulation of the anterior pituitary gland function by the hypothalamus.

Search more.