HBx-induced reactive oxygen species activates hepatocellular carcinogenesisviadysregulation of PTEN/Akt pathway (scientific article published on October 21, 2010)

Hepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-Jun N-terminal mitogen-activated protein kinases

Q35865743

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

Q36266420

The role of PTEN signaling perturbations in cancer and in targeted therapy

Q37270446

Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

Q37693081

HBx protein of hepatitis B virus activates Jak1-STAT signaling

Q38333320

Proteomic analysis of liver tissue from HBx-transgenic mice at early stages of hepatocarcinogenesis.

Q38491961

Gender-dependent hepatic alterations in H-ras12V transgenic mice

Q38513308

Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells

Q38518392

Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein

Q38527672

Hepatitis B virus pX targets TFIIB in transcription coactivation

Q39574625

Hepatitis B virus pX activates NF-kappa B-dependent transcription through a Raf-independent pathway

Q39873232

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

Q40525865

The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

Q40816601

Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells

Q43883726

Biology of hepatitis B virus.

Q45801993

Hepatocyte growth factor promotes cell survival from fas-mediated cell death in hepatocellular carcinoma cells via Akt activation and Fas-death-inducing signaling complex suppression

Q72996740

Cellular non-heme iron content is a determinant of nitric oxide-mediated apoptosis, necrosis, and caspase inhibition

Q73643152

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

carcinogenesis

Q1637543

reactive oxygen species

Q424361

signal transduction

Q828130

P304

page(s)

4932-4937

P577

publication date

2010-10-01

2010-10-21

P1433

published in

World Journal of Gastroenterology

Q15708885

P1476

title

HBx-induced reactive oxygen species activates hepatocellular carcinogenesis via dysregulation of PTEN/Akt pathway

HBx-induced reactive oxygen species activates hepatocellular carcinogenesisviadysregulation of PTEN/Akt pathway

P478

volume

Reverse relations

cites work (P2860)

Q38619642	DNA damage response and sphingolipid signaling in liver diseases
Q38001126	Do hepatitis B virus and hepatitis C virus co-infections increase hepatocellular carcinoma occurrence through synergistically modulating lipogenic gene expression?
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Q34856882	Functional implications of mitochondrial reactive oxygen species generated by oncogenic viruses
Q34742600	Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1.
Q33802988	Hepatitis B virus X stimulates redox signaling through activation of ataxia telangiectasia mutated kinase
Q36349941	Hepatitis B virus stimulates G6PD expression through HBx-mediated Nrf2 activation
Q34760443	Hydrogen sulfide prevents hydrogen peroxide-induced activation of epithelial sodium channel through a PTEN/PI(3,4,5)P3 dependent pathway
Q55493284	Identification of anti-SF3B1 autoantibody as a diagnostic marker in patients with hepatocellular carcinoma.
Q38440403	Investigating genetic characteristics of hepatitis B virus-associated and -non-associated hepatocellular carcinoma.
Q36432730	Modulation of apoptotic signaling by the hepatitis B virus X protein
Q26823512	Molecular mechanism of hepatitis B virus-induced hepatocarcinogenesis
Q92644648	Nanocarrier-mediated antioxidant delivery for liver diseases
Q28075646	Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis
Q64134231	Peroxiredoxin 1, a Novel HBx-Interacting Protein, Interacts with Exosome Component 5 and Negatively Regulates Hepatitis B Virus (HBV) Propagation through Degradation of HBV RNA
Q90036169	Peroxiredoxin 5 ameliorates obesity-induced non-alcoholic fatty liver disease through the regulation of oxidative stress and AMP-activated protein kinase signaling
Q35185336	ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells
Q36625600	ROS-mediated activation of AKT induces apoptosis via pVHL in prostate cancer cells
Q37287538	ROS-mediated regulation of CXCR4 in cancer.
Q38780065	Reactive Oxygen Species-Mediated c-Jun NH2-Terminal Kinase Activation Contributes to Hepatitis B Virus X Protein-Induced Autophagy via Regulation of the Beclin-1/Bcl-2 Interaction
Q90612437	Relevance of reactive oxygen species in liver disease observed in transgenic mice expressing the hepatitis B virus X protein
Q90607894	Role of alcohol in pathogenesis of hepatitis B virus infection
Q92296353	Serum anti-EIF3A autoantibody as a potential diagnostic marker for hepatocellular carcinoma
Q37900925	The molecular and pathophysiological implications of hepatitis B X antigen in chronic hepatitis B virus infection

P356	DOI	10.3748/WJG.V16.I39.4932
P953	full work available at URL	https://doi.org/10.3748/wjg.v16.i39.4932
		https://europepmc.org/articles/PMC2957601
		https://europepmc.org/articles/PMC2957601?pdf=render
P932	PMC publication ID	2957601
P698	PubMed publication ID	20954279
P5875	ResearchGate publication ID	50346584