CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells

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CD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1400798
P932PMC publication ID4170672
P698PubMed publication ID25172502
P5875ResearchGate publication ID265176756

P2093author name stringDavid J Rawlings
Socheath Khim
Marc A Schwartz
Nikita S Kolhatkar
Chris Thouvenel
P2860cites workPeripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cellsQ28264835
Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45Q28592092
Predominant autoantibody production by early human B cell precursorsQ29619656
Most peripheral B cells in mice are ligand selectedQ33387224
B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.Q33869680
B cells require "nurturing" by CD4 T cells during development in order to respond in chronic graft-versus-host model of systemic lupus erythematosusQ33936174
BAFF Receptor Signaling Aids the Differentiation of Immature B Cells into Transitional B Cells following Tonic BCR SignalingQ34179934
Development of self-reactive germinal center B cells and plasma cells in autoimmune Fc gammaRIIB-deficient mice.Q34340586
Naive CD4 T cells constitutively express CD40L and augment autoreactive B cell survivalQ34702800
WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunityQ35237494
Regulation of B-cell development by antibody specificityQ35692219
Endogenous antigen tunes the responsiveness of naive B cells but not T cellsQ36223587
CD40 ligand and MHC class II expression are essential for human peripheral B cell toleranceQ36229478
BAFF and MyD88 signals promote a lupuslike disease independent of T cellsQ36229560
Selection of antigen-specific, idiotype-positive B cells in transgenic mice expressing a rearranged M167-mu heavy chain geneQ36230528
Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansionQ36267196
Lack of mature B cells in nude mice with X-linked immune deficiencyQ36346268
Light chain replacement: a new model for antibody gene rearrangementQ36365220
Autoreactive B cells in the marginal zone that express dual receptorsQ36369869
Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferationQ36446940
Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivityQ36547706
Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturationQ36626153
The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.Q36768345
Peripheral B cell subsetsQ36867717
Autoimmunity in hyper-IgM syndrome.Q37075978
BAFF and the plasticity of peripheral B cell toleranceQ37154487
Transitional B cells exhibit a B cell receptor-specific nuclear defect in gene transcriptionQ37221911
Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.Q37347235
Cracking the BAFF code.Q37517172
B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor.Q37781397
Translational Mini-Review Series on B cell subsets in disease. Reconstitution after haematopoietic stem cell transplantation - revelation of B cell developmental pathways and lineage phenotypesQ37963475
Receptor-mediated elimination of phosphocholine-specific B cells in x-linked immune-deficient mice.Q41162441
Function of bone marrow stromal cell lines derived from nude mice.Q41448803
Immunoglobulin analysis tool: a novel tool for the analysis of human and mouse heavy and light chain transcriptsQ41813717
PI3 kinase signals BCR-dependent mature B cell survivalQ41886641
Selection of antibody repertories: transfer of mature T lymphocytes modifies VH gene family usage in the actual and available B cell repertories of athymic miceQ42800471
Evidence for a ligand-mediated positive selection signal in differentiation to a mature B cellQ47333916
Light chain contribution to specificity in anti-DNA antibodiesQ48070592
Cloning and expression of murine Ig genes from single B cells.Q52908841
An Essential Role for BAFF in the Normal Development of B Cells Through a BCMA-Independent PathwayQ57230082
Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.Q64890383
B cell deficiency progresses with lineage maturation in nude.X-linked immunodeficient mice B cell deficiency progresses with lineage maturationQ67900791
Profound reduction of mature B cell numbers, reactivities and serum Ig levels in mice which simultaneously carry the XID and CD40 deficiency genesQ71834262
Impaired B cell maturation in mice lacking Bruton's tyrosine kinase (Btk) and CD40Q73193967
Cutting edge: B cell receptor signals regulate BLyS receptor levels in mature B cells and their immediate progenitorsQ73496335
B cell receptor-induced apoptosis in primary transitional murine B cells: signaling requirements and modulation by T cell helpQ77658978
Positive selection of natural autoreactive B cellsQ77950133
B cell positive selection by soluble self-antigenQ78346711
Naive B lymphocytes undergo homeostatic proliferation in response to B cell deficitQ78625964
T cells are required for the peripheral phase of B-cell maturationQ81373802
The role of CD154 in haematopoietic developmentQ84699936
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)3492-3502
P577publication date2014-08-29
P1433published inJournal of ImmunologyQ3521441
P1476titleCD4+ T cells and CD40 participate in selection and homeostasis of peripheral B cells
P478volume193

Reverse relations

cites work (P2860)
Q33924642Altered B cell signalling in autoimmunity
Q36080732Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome
Q36372629BCR and co-receptor crosstalk facilitate the positive selection of self-reactive transitional B cells
Q50614844Comparative Evaluation of αCD40 (2C10R4) and αCD154 (5C8H1 and IDEC-131) in a Nonhuman Primate Cardiac Allotransplant Model.
Q33419834Critical role of CD4 T cells in PF4/heparin antibody production in mice
Q36905439Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells
Q38988830Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease
Q94550943Homeostasis and regulation of autoreactive B cells
Q37737830Mediation of transitional B cell maturation in the absence of functional Bruton's tyrosine kinase
Q100753730Mycobacterium tuberculosis PPE18 protein inhibits MHC class II antigen presentation and B cell response in mice
Q39424886Role of Sex Hormone Levels and Psychological Stress in the Pathogenesis of Autoimmune Diseases
Q64094866Sex Differences in Older Adults' Immune Responses to Seasonal Influenza Vaccination
Q37427351Somatically Hypermutated Plasmodium-Specific IgM(+) Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge
Q34551079T cell-B cell thymic cross-talk: maintenance and function of thymic B cells requires cognate CD40-CD40 ligand interaction
Q38628322The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
Q56944872αv Integrins regulate germinal center B cell responses through noncanonical autophagy

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