| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Seligsohn U | |
| Lubetsky A | |||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | thrombosis | Q261327 |
| P304 | page(s) | 1222-1231 | |
| P577 | publication date | 2001-04-01 | |
| P1433 | published in | The New England Journal of Medicine | Q582728 |
| P1476 | title | Genetic susceptibility to venous thrombosis | |
| P478 | volume | 344 |
| Q46636636 | A case control study on the contribution of factor V-Leiden, prothrombin G20210A, and MTHFR C677T mutations to the genetic susceptibility of deep venous thrombosis |
| Q37672733 | A delayed presentation of homozygous protein C deficiency in a series of children: a report on two molecular defects |
| Q52943650 | A negative personal and family history for venous thrombotic events is not sufficient to exclude thrombophilia in patients with cerebral venous thrombosis. |
| Q44435049 | A survey of the clinical course and management of Japanese patients deficient in natural anticoagulants |
| Q47973287 | A systematic review of cost-effectiveness analysis of screening interventions for assessing the risk of venous thromboembolism in women considering combined oral contraceptives. |
| Q53929284 | Activated protein C resistance acquired through liver transplantation and associated with recurrent venous thrombosis. |
| Q88984497 | Activated protein C, protease activated receptor 1, and neuroprotection |
| Q91877901 | Acute pulmonary thromboembolism caused by factor V Leiden mutation in South Korea: A case report |
| Q30999491 | Age, an independent risk factor for thrombosis. Epidemiologic data |
| Q36674553 | Antibody SPC-54 provides acute in vivo blockage of the murine protein C system. |
| Q36277248 | Antithrombotic therapy for stroke in young adults |
| Q47440459 | Are Prothrombotic Mutations a Time-to-Event Risk Factor? |
| Q47930555 | Assessing the coagulation factor levels, inherited thrombophilia, and ABO blood group on the risk for venous thrombosis among Brazilians |
| Q36879725 | Association between Thrombophilia and the Post-Thrombotic Syndrome |
| Q39206682 | Associations between polymorphisms in coagulation-related genes and venous thromboembolism: A meta-analysis with trial sequential analysis |
| Q64121947 | Asymmetric independence modeling identifies novel gene-environment interactions |
| Q35535961 | British Thoracic Society guidelines for the management of suspected acute pulmonary embolism |
| Q26775796 | Budd-Chiari syndrome |
| Q43286564 | Cardiovascular risk factors and outcome in patients with retinal vein occlusion |
| Q44942513 | Central venous line thrombosis in children and young adults with thalassemia major |
| Q48433542 | Cerebral cortical and deep venous thrombosis without sinus thrombosis: clinical MRI correlates. |
| Q92495646 | Cerebral sinovenous thrombosis in a child with ulcerative colitis: A case report |
| Q30802477 | Cerebral venous thrombosis in adults: the role of imaging evaluation and management |
| Q47873878 | Cilioretinal artery: Vasculogenesis might be promoted by plasminogen activator inhibitor-1 5G allele |
| Q36610222 | Clinical Presentation, Imaging and Treatment of Cerebral Venous Thrombosis (CVT). |
| Q35103077 | Clinical and laboratory evaluation of thrombophilia |
| Q37035275 | Combination of thrombophilic gene polymorphisms as a cause of increased the risk of recurrent pregnancy loss |
| Q36595087 | Common genetic risk factors for venous thrombosis in the Chinese population |
| Q75183805 | Comprehensive hypercoagulable state testing is indicated in patients with a first idiopathic deep venous thrombosis |
| Q40518393 | Concomitant homozygosity for the prothrombin gene variant with mild deficiency of antithrombin III in a patient with multiple hepatic infarctions: a case report |
| Q37711420 | Congenital Thrombophilia and Intracardiac Thrombosis: Probably an Underdiagnosed Event |
| Q37763366 | Congenital thrombophilia and central venous catheter-related thrombosis in patients with cancer |
| Q54477522 | Correlation between single nucleotide polymorphism of prothrombin gene G20210 and deep vein thrombosis after total joint replacement in Chinese patients. |
| Q79889257 | Corticosteroid-responsive Cronkhite-Canada syndrome complicated by thrombosis |
| Q38117729 | Current knowledge on the genetics of incident venous thrombosis. |
| Q73315638 | Deep venous thrombosis associated with factor V Leiden, G20210A mutation, and protein S deficiency |
| Q37807428 | Diagnostic algorithm for thrombophilia screening |
| Q35407942 | Diagnostic ramifications of ocular vascular occlusion as a first thrombotic event associated with factor V Leiden and prothrombin gene heterozygosity |
| Q37618937 | Distinct frequencies and mutation spectrums of genetic thrombophilia in Korea in comparison with other Asian countries both in patients with thromboembolism and in the general population |
| Q48733927 | Donor Selection and Prophylactic Strategy for Venous Thromboembolic Events in Living Donors of Liver Transplantation Based on Results of Thrombophilia Screening Tests |
| Q51704221 | Donor screening algorithm for exclusion of thrombophilia during evaluation of living donor liver transplantation. |
| Q53641315 | Dural sinus thrombosis presenting three months postpartum |
| Q35547228 | Duration of Anticoagulant Therapy after Initial Idiopathic Venous Thromboembolism |
| Q42071764 | Endothelial cell protein C receptor gene 6936A/G polymorphism is associated with venous thromboembolism |
| Q34979126 | Endovascular management of venous thrombotic diseases of the upper torso and extremities. |
| Q51768193 | Estimated incidence of acute pulmonary embolism in a Korean hospital. |
| Q34439986 | Evaluation of GenoFlow Thrombophilia Array Test Kit in its detection of mutations in Factor V Leiden (G1691A), prothrombin G20210A, MTHFR C677T and A1298C in blood samples from 113 Turkish female patients |
| Q33340971 | Evaluation of women with clinically suspected thrombotic thrombocytopenic purpura-hemolytic uremic syndrome during pregnancy |
| Q73690544 | Exercise-induced activation of coagulation in thrombophilia |
| Q34376129 | Extended outpatient therapy with low molecular weight heparin for the treatment of recurrent venous thromboembolism despite warfarin therapy |
| Q37810984 | Factor V Leiden and FII 20210 testing in thromboembolic disorders |
| Q77563058 | Factor V Leiden and prothrombin gene mutation in inflammatory bowel disease in a Mediterranean area |
| Q73270914 | Factor V Leiden and prothrombin gene mutation may predispose to paradoxical embolism in subjects with patent foramen ovale |
| Q36929427 | Factor V Leiden, Prothrombin and MTHFR Mutation in Patients with Preeclamsia, Intrauterine Growth Restriction and Placental Abruption |
| Q53283183 | Family history unawareness of blood clot risk: links to misdiagnoses and illness uncertainties in personal and expert realms. |
| Q48183072 | Fatal Dural Sinus Thrombosis Associated With Heterozygous Factor V Leiden and a Short Activated Partial Thromboplastin Time |
| Q54306982 | Frequency of thrombophilic genetic polymorphisms among Saudi subjects compared with other populations. |
| Q36516202 | Full trisomy 5 in a sample of spontaneous abortion and Arias Stella reaction. |
| Q36267584 | Genetic risk factors in patients with deep venous thrombosis, a retrospective case control study on Iranian population |
| Q35569570 | Genetic variation and hematology: single-nucleotide polymorphisms, haplotypes, and complex disease |
| Q36697910 | Genetics of coagulation: considerations for cardiac surgery |
| Q90581976 | Genotypic and phenotypic character of Chinese neonates with congenital protein C deficiency: a case report and literature review |
| Q35134491 | Gestational vascular complications |
| Q37175229 | Gross deletions/duplications in PROS1 are relatively common in point mutation-negative hereditary protein S deficiency. |
| Q36793856 | Haemophilia A: molecular insights. |
| Q35824844 | Haemophilia and thrombophilia: an unexpected association! |
| Q44048852 | Hereditary thrombophilias are not associated with a decreased live birth rate in women with recurrent miscarriage |
| Q46982006 | Hereditary thrombophilic risk factors and venous thromboembolism in Istanbul, Turkey: the role in different clinical manifestations of venous thromboembolism |
| Q35263482 | Hereditary thrombophilic risk factors for recurrent pregnancy loss. |
| Q47173175 | Homozygous protein C deficiency presenting as neonatal purpura fulminans: management with fresh frozen plasma, low molecular weight heparin and protein C concentrate |
| Q37040260 | Hypercoagulable State |
| Q89002092 | Hypercoagulable States and Thrombophilias: Risks Relating to Recurrent Venous Thromboembolism |
| Q37809540 | Hypercoagulable state, pathophysiology, classification and epidemiology |
| Q33365671 | Hypercoagulable states: a review |
| Q35788910 | Hyperhomocysteinemia and other thrombophilic risk factors in 26 patients with cerebral venous thrombosis. |
| Q33904517 | Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes |
| Q52313102 | Incidence and risk factors for venous thromboembolism in patients with pretreated advanced pancreatic carcinoma. |
| Q26830337 | Inflammatory bowel disease and thrombosis |
| Q30502980 | Inflammatory bowel disease: perioperative pharmacological considerations |
| Q36918916 | Influence of genetic and environmental factors in peripheral arterial disease natural history: Analysis from six years follow up. |
| Q73429700 | Inherited thrombophilia and gestational venous thromboembolism |
| Q36808748 | Inherited thrombophilia: key points for genetic counseling |
| Q44352953 | Internal jugular vein thrombosis after cocaine inhalation in a woman with factor V Leiden |
| Q37302477 | Is thrombophilia a major risk factor for deep vein thrombosis of the lower extremities among Lebanese patients? |
| Q79312615 | Knowledge and educational needs of individuals with the factor V Leiden mutation |
| Q34981644 | Laboratory thrombophilias and venous thromboembolism |
| Q37903948 | Lessons from genome-wide association studies in venous thrombosis. |
| Q36725777 | Litigation in obstetrics: a lesson learnt and a lesson to share |
| Q57969761 | Long-term outcomes of patients with cerebral vein thrombosis: a multicenter study |
| Q45880590 | Low borderline plasma levels of antithrombin, protein C and protein S are risk factors for venous thromboembolism |
| Q46396909 | Low-molecular weight heparin in patients with recurrent early miscarriages of unknown aetiology |
| Q40553268 | MRI diagnosis of bilateral adrenal vein thrombosis |
| Q51587661 | Magnetic resonance venography and genetics of a female patient with pelvic venous thrombosis. |
| Q26749273 | Management of Venous Thromboembolisms: Part I. The Consensus for Deep Vein Thrombosis |
| Q83832805 | Management of acute portomesenteric venous thrombosis induced by protein S deficiency: report of a case |
| Q51174537 | Management of concomitant factor VII deficiency and Factor V Leiden mutation. |
| Q36718482 | Management of patients with unprovoked venous thromboembolism: an evidence-based and practical approach |
| Q53951576 | Markers of activated coagulation in patients with factor V Leiden and/or G20210A prothrombin gene mutation. |
| Q42213727 | Massive exploration of perturbed conditions of the blood coagulation cascade through GPU parallelization |
| Q50800553 | Maternal factor V Leiden and prothrombin mutations do not seem to contribute to the occurrence of two or more than two consecutive miscarriages in Caucasian patients. |
| Q35964451 | Mechanism and pathophysiology of activated protein C-related factor V leiden in venous thrombosis |
| Q30717783 | Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data |
| Q78725862 | Mid-trimester severe intrauterine growth restriction is associated with a high prevalence of thrombophilia |
| Q48127644 | Necessity and risks of arterial blood sampling in healthy volunteer studies |
| Q50160432 | Neonatal thrombo-embolism: risk factors, clinical features and outcome |
| Q33184450 | Neuroimaging fails to identify asymptomatic carriers of familial porencephaly |
| Q58215078 | No increased venous thromboembolism risk in Asian breast cancer patients receiving adjuvant tamoxifen |
| Q88427464 | Non-O blood group and outcomes of in vitro fertilization |
| Q33921617 | Normal levels of protein C and protein S tested in the acute phase of a venous thromboembolic event are not falsely elevated |
| Q36324218 | Ocular manifestations of crush head injury in children |
| Q39266304 | Optimal utilization of thrombophilia testing |
| Q34966977 | Oral contraception and the risk of thromboembolism: what does it mean to clinicians and their patients? |
| Q36427616 | Oral contraceptives and the risk of venous thromboembolism |
| Q81149769 | PROS1 analysis in 87 pedigrees with hereditary protein S deficiency demonstrates striking genotype-phenotype associations |
| Q78651369 | Parameters of coagulant and fibrinolytic capacity and activity in postmenopausal women: within-subject variability |
| Q84206513 | Patent foramen ovale and stroke: Should PFOs be closed in otherwise cryptogenic stroke? |
| Q37168212 | Perinatal renal venous thrombosis: presenting renal length predicts outcome |
| Q35204081 | Pharmacogenetics of CYP2C9 and interindividual variability in anticoagulant response to warfarin |
| Q44772500 | Pharmacokinetics of recombinant human antithrombin in delivery and surgery patients with hereditary antithrombin deficiency. |
| Q38805421 | Polymorphisms of the coagulation system and risk of cancer |
| Q38073655 | Portal vein thrombosis: should anticoagulation be used? |
| Q40989421 | Portomesenteric venous thrombosis as a rare cause of acute abdomen in a young patient: What should be the process of diagnosis and management? |
| Q81721667 | Postoperative venous thromboembolism rates vary significantly after different types of major abdominal operations |
| Q35784521 | Predicting disease using genomics |
| Q79129561 | Pregnancy‐associated venous thromboembolism (VTE) in combined heterozygous factor V Leiden (FVL) and prothrombin (FII) 20210 A mutation and in heterozygous FII single gene mutation alone |
| Q36030393 | Prenatal screening for thrombophilia: the background and the approach |
| Q54571473 | Prevalence of Factor V 1691 G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients. |
| Q54374142 | Prevalence of H1299R polymorphism in the Factor V gene among the Taif-Saudi Arabia population using polymerase chain reaction-reverse hybridization technique. |
| Q54606688 | Prevalence of factor V Leiden and prothrombin G20210A mutations in Chinese patients with deep venous thrombosis and pulmonary embolism. |
| Q34502105 | Prevalence of inherited antithrombin, protein C, and protein S deficiencies in portal vein system thrombosis and Budd-Chiari syndrome: a systematic review and meta-analysis of observational studies. |
| Q51804641 | Prevalence of prothrombin gene mutation (G-A 20210 A) in general population: a pilot study. |
| Q41698421 | Prevalence of resistence to activated protein C (APC-resistance) in blood donors in Kosovo |
| Q81751855 | Prevalence of the Factor V G1691A and the Factor II/prothrombin G20210A gene polymorphisms among Tamilians |
| Q33899305 | Prevalence of thrombophilia in asymptomatic individuals with a family history of thrombosis |
| Q41932077 | Prevalence of thrombophilic mutations in patients with unprovoked thromboembolic disease. A comparative analysis regarding arterial and venous disease |
| Q92712661 | Prophylaxis and Therapy of Venous Thrombotic Events (VTE) in Pregnancy and the Postpartum Period |
| Q34316337 | Protein C deficiency. |
| Q37163507 | Protein S deficiency: a clinical perspective |
| Q44052683 | Protein S gene mutation in a young woman with type III protein S deficiency and venous thrombosis during pregnancy |
| Q79889187 | Prothrombin 20210 G/A defect as a cause of mesenteric venous infarction: report of a case |
| Q45138871 | Prothrombotic risk factors in infants of diabetic mothers |
| Q79954098 | Pulmonary embolism |
| Q30476617 | Pulmonary embolism in hospital practice |
| Q50997832 | R147W in PROC Gene Is a Risk Factor of Thromboembolism in Thai Children. |
| Q35691663 | Racial differences in the prevalence of Factor V Leiden mutation among patients on chronic warfarin therapy |
| Q64228949 | Re-Examining Genetic Screening and Oral Contraceptives: A Patient-Centered Review |
| Q37099148 | Recent advances in cardiorespiratory medicine: management of pulmonary embolism and prevention of venous thromboembolism, recent treatment strategies in childhood asthma, and dermatological adverse reactions to cardiovascular drugs |
| Q33361019 | Recurrent life-threatening thromboembolism and catastrophic antiphospholipid syndrome in a patient despite sufficient oral anticoagulation |
| Q49252439 | Recurrent mutations in a SERPINC1 hotspot associate with venous thrombosis without apparent antithrombin deficiency |
| Q55086607 | Recurrent pulmonary embolism associated with deep venous thrombosis diagnosed as protein s deficiency owing to a novel mutation in PROS1: A case report. |
| Q47232464 | Reduced Protein C Global Assay Levels in Infertile Women with in vitro Fertilization Failure: A Pilot Study |
| Q37538802 | Reduced protein C Global assay level in infertile women prior to IVF-ET treatment |
| Q41253045 | Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis |
| Q37174819 | Retinal vascular occlusion: a window to diagnosis of familial and acquired thrombophilia and hypofibrinolysis, with important ramifications for pregnancy outcomes |
| Q35158989 | Review article: inherited thrombophilia in inflammatory bowel disease |
| Q36094372 | Review of thrombophilic States |
| Q46391990 | Risk Factors and Treatment Strategies in Patients With Retinal Vascular Occlusions |
| Q34153343 | Risk assessment for recurrent venous thrombosis |
| Q35134507 | Risk factors for thrombosis in pregnancy |
| Q34988616 | Risk factors for venous and arterial thrombosis |
| Q80485832 | Risk factors of venous thromboembolism in thai patients |
| Q41153519 | Risk prediction of developing venous thrombosis in combined oral contraceptive users |
| Q44556178 | Role of factor V Leiden and prothrombin 20210A in patients with retinal artery occlusion |
| Q45924520 | Sclerotherapy of varicose veins in patients with documented thrombophilia: a prospective controlled randomized study of 105 cases. |
| Q35148395 | Screening for hypercoagulable syndromes following stroke |
| Q78513929 | Significant influence of the instrument on the result of the ProC Global assay. A multicenter evaluation using lyophilized plasmas and frozen plasma samples from carriers and non-carriers of the factor V Leiden mutation |
| Q104064471 | Silk fibroin vascular graft: a promising tissue-engineered scaffold material for abdominal venous system replacement |
| Q35747532 | Simultaneous sequencing of multiple polymerase chain reaction products and combined polymerase chain reaction with cycle sequencing in single reactions |
| Q37922590 | Splanchnic vein thrombosis in the mediterranean area in children |
| Q50779627 | Stroke recurrence and its prevention in patients with patent foramen ovale. |
| Q34346972 | Study of associated genetic variants in Indian subjects reveals the basis of ethnicity related differences in susceptibility to venous thromboembolism |
| Q38411008 | Technical validation of a multiplex platform to detect thirty mutations in eight genetic diseases prevalent in individuals of Ashkenazi Jewish descent |
| Q36176002 | The 5, 10 methylenetetrahydrofolate reductase C677T mutation and risk of fetal loss: a case series and review of the literature |
| Q33384534 | The G1691A mutation of the factor V gene (factor V Leiden) and the G20210A mutation of the prothrombin gene as risk factors in thrombotic microangiopathies |
| Q35736976 | The Prevalence of the Prothrombin (F2) 20210G>A Mutation in a Cohort of Sri Lankan Patients with Thromboembolic Disorders |
| Q33403489 | The challenge of managing hemophilia A and STEC-induced hemolytic uremic syndrome |
| Q47644500 | The diagnosis and treatment of venous thromboembolism in asian patients. |
| Q38829586 | The discovery of dabigatran etexilate for the treatment of venous thrombosis |
| Q34754709 | The epidemiology of peripheral vein infusion thrombophlebitis: a critical review |
| Q33376809 | The homozygous leu variant of the factor XIII Val34Leu polymorphism as a risk factor for the manifestation of thrombotic microangiopathies |
| Q36251390 | The impact of prothrombin (G20210A) gene mutation on stroke in youths |
| Q35145555 | The inherited thrombophilias: genetics, epidemiology, and laboratory evaluation |
| Q40632496 | The intronic prothrombin 19911A>G polymorphism influences splicing efficiency and modulates effects of the 20210G>A polymorphism on mRNA amount and expression in a stable reporter gene assay system |
| Q78609465 | The management of thrombophilia during pregnancy: a Canadian survey |
| Q37817023 | The plasmin-antiplasmin system: structural and functional aspects |
| Q44783403 | The prevalence of factor V G1691A but not of prothrombin G20210A and methylenetetrahydrofolate reductase C677T is remarkably low in French Basques |
| Q38961168 | The prothrombin 20209 C-->T mutation in Jewish-Moroccan Caucasians: molecular analysis of gain-of-function of 3' end processing |
| Q33202663 | The role of genetics in the risk of thromboembolism: prothrombin 20210A and oral contraceptive therapy |
| Q38250442 | The role of hemostasis in infective endocarditis |
| Q99578847 | Three-factorial Genetic Thrombophilia with Recurrent Thrombotic Events in a Saudi Patient: A Case Report |
| Q36030420 | Thromboembolic diseases in neonates and children |
| Q90734293 | Thrombophilia Caused by Beta2-Glycoprotein I Deficiency: In Vitro Study of a Rare Mutation in APOH Gene |
| Q37326644 | Thrombophilia and anticoagulation in pregnancy: indications, risks and management |
| Q36964402 | Thrombophilia in Korean patients with arterial or venous thromboembolisms |
| Q46952104 | Thrombophilia in patients with chronic venous leg ulcers-a study on patients with or without post-thrombotic syndrome |
| Q35089523 | Thrombophilic disorders and fetal loss: a meta-analysis |
| Q43257560 | Thrombophilic factors do not predict outcomes in renal transplant recipients under prophylactic acetylsalicylic acid |
| Q35871067 | Thrombophilic polymorphisms are not associated with disease-free survival in breast cancer patients |
| Q90190642 | Thrombophilic risk factors in hemodialysis: Association with early vascular access occlusion and patient survival in long-term follow-up |
| Q44404144 | Thrombophilic screening in Turner syndrome. |
| Q78437590 | Thrombotic events in compound heterozygotes for a high affinity hemoglobin variant: Hb Milledgeville [alpha44(CE2)Pro-->Leu (alpha2)] and factor V Leiden |
| Q34469151 | Update on selected inherited venous thrombotic disorders |
| Q48901051 | Use of intravenous tissue plasminogen activator in a 16-year-old patient with basilar occlusion |
| Q34426096 | Using genetic variation to study human disease |
| Q33165033 | Varicose vein trauma: a risk for pulmonary embolism |
| Q35800317 | Vena caval filters: a review for intensive care specialists |
| Q79878090 | Venous Thrombolysis: Current Perspectives |
| Q35016604 | Venous thromboembolism: implications for gene-based diagnosis and technology development |
| Q89777077 | Whole-exome sequencing in evaluation of patients with venous thromboembolism |
| Q74339763 | [Coronary thrombosis on patient with the factor V Leiden mutation] |
| Q53645012 | [Current controversies in the diagnosis and management of cerebral venous and dural sinus thrombosis]. |
| Q78627372 | [Duration of oral anticoagulant therapy in deep venous thrombosis of the lower limbs] |
| Q77499582 | [Duration of oral anticoagulant therapy in venous thromboembolism] |
| Q78627365 | [Genetic risk factors of thrombosis] |
| Q77616306 | [Hormonal oral contraceptives, coagulation and thrombosis] |
| Q74362959 | [Recurrent venous thromboembolism with increase of factor VIII and familial clustering] |
| Q77727472 | [Risk associated with thrombophilia and pregnancy] |
| Q53609860 | [Spontaneous resolution of extensive superior mesenteric and portal vein thrombosis. A case report] |
| Q83731122 | [Thrombosis prophylaxis in geriatric patients] |
| Q74738835 | thrombophilia in childhood hemolytic uremic syndrome |
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