Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells

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Differential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI117381
P932PMC publication ID296142
P698PubMed publication ID8040318

P2093author name stringR W Lambrecht
H L Bonkovsky
E E Cable
J A Pepe
N C Karamitsios
P2860cites workRegulation of heme oxygenase and metallothionein gene expression by the heme analogs, cobalt-, and tin-protoporphyrinQ28267649
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Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudineQ28334930
Heme control on the synthesis of delta-aminolevulinic acid synthetase in cultured chick embryo liver cellsQ28336141
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Expression of delta-aminolevulinate synthase in avian cells: separate genes encode erythroid-specific and nonspecific isozymesQ33833853
Zinc Protoporphyrin in the Erythrocytes of Patients with Lead Intoxication and Iron Deficiency AnemiaQ34052261
Early administration of heme arginate for acute porphyric attacksQ34061438
Effect of heme arginate administration on blood pressure in spontaneously hypertensive ratsQ34256145
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Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liverQ34614879
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ACUTE INTERMITTENT PORPHYRIA: THE FIRST "OVERPRODUCTION DISEASE" LOCALIZED TO A SPECIFIC ENZYMEQ36397053
Repression of the Overproduction of Porphyrin Precursors in Acute Intermittent Porphyria by Intravenous Infusions of HematinQ37491123
Porphyrogenic properties of the terpenes camphor, pinene, and thujone (with a note on historic implications for absinthe and the illness of Vincent van Gogh).Q38513940
Heme in the treatment of porphyrias and hematological disordersQ38607208
Control of heme biosynthesis in animals.Q38637468
Prevention of acute porphyric attacks by intravenous haematinQ39503048
Effects by heme, insulin, and serum albumin on heme and protein synthesis in chick embryo liver cells cultured in a chemically defined medium, and a spectrofluorometric assay for porphyrin compositionQ41075748
Hematin Therapy for Acute PorphyriaQ41642635
Estimation of relative mRNA content by filter hybridization to a polythymidylate probeQ41726171
Mortality of metalloporphyrin-treated neonatal rats after light exposure.Q41845678
Haem arginate in the treatment of acute hepatic porphyriasQ41956065
Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metalsQ41970034
Conversion of 5-aminolaevulinate into haem by liver homogenates. Comparison of rat and chick embryoQ42137138
Regulation of the stability of chicken embryo liver delta-aminolevulinate synthase mRNA by heminQ42198539
The effects of haem arginate and haematin upon the allylisopropylacetamide induced experimental porphyria in ratsQ42219333
The effects of metalloporphyrins, porphyrins and metals on the activity of delta-aminolevulinic acid synthase in monolayers of chick embryo liver cellsQ42249903
Long-term bone marrow stromal and hemopoietic toxicity to AZT: protective role of heme and IL-1Q42277983
Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photoreactivityQ42289321
Conversion of 5-aminolaevulinate into haem by homogenates of human liver. Comparison with rat and chick-embryo liver homogenatesQ42849557
Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme poolsQ43898909
In Vitro and In Vivo Characteristics of a Heme Oxygenase Inhibitor: ZnBGQ44130874
Synergistic induction of delta-aminolevulinate synthase by glutethimide and iron: relationship to the synergistic induction of heme oxygenaseQ44627675
Effects of oral administration of tin and zinc protoporphyrin on neonatal and adult rat tissue heme oxygenase activityQ46112694
Tin-protoporphyrin-mediated disruption in vivo of heme oxygenase-2 protein integrity and activity in rat brainQ48437938
Molecular basis for heme-dependent induction of heme oxygenase in primary cultures of chick embryo hepatocytes. Demonstration of acquired refractoriness to heme.Q54240719
Repression of hepatic delta-aminolevulinate synthase by heme and metalloporphyrins: relationship to inhibition of heme oxygenase.Q55066137
Transitory renal failure following rapid administration of a relatively large amount of hematin in a patient with acute intermittent porphyria in clinical remissionQ67348702
Thrombophlebitis and disturbed hemostasis following administration of intravenous hematin in normal volunteersQ67945151
Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcriptionQ67981471
Haem-arginate plus tin-protoporphyrin for acute hepatic porphyriaQ68307156
Mechanism of synergistic induction of hepatic heme oxygenase by glutethimide and iron: studies in cultured chick embryo liver cellsQ68758358
Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolismQ69050176
Instability of hematin used in the treatment of acute hepatic porphyriaQ69554140
Circulatory collapse associated with hemin therapy for acute intermittent porphyriaQ69588623
Haem arginate: a new stable haem compoundQ69910675
Haem arginate treatment for hereditary sideroblastic anaemiaQ69942072
Hematin-induced hemolysis in acute porphyriaQ70665711
Biogenesis of mitochondrial proteins. Identification of the mature and precursor forms of the subunit of delta-aminolevulinate synthase from embryonic chick liverQ70875625
Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal modelQ71861266
Tin protoporphyrin prolongs the biochemical remission produced by heme arginate in acute hepatic porphyriaQ72840955
Advances in understanding and treating 'the little imitator,' acute porphyriaQ72840988
The induction in vitro of the synthesis of delta-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicalsQ72843058
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)649-654
P577publication date1994-08-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleDifferential effects of metalloporphyrins on messenger RNA levels of delta-aminolevulinate synthase and heme oxygenase. Studies in cultured chick embryo liver cells
P478volume94

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cites work (P2860)
Q34555359Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal
Q34811695Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin
Q53702123Effects of selected antihypertensives and analgesics on hepatic porphyrin accumulation: implications for clinical porphyria.
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Q39173986Heme status affects human hepatic messenger RNA and microRNA expression.
Q41745519Management of acute attacks in the porphyrias
Q42550394Mechanism of induction of heme oxygenase by metalloporphyrins in primary chick embryo liver cells: evidence against a stress-mediated response
Q41043697Mechanism of sodium arsenite-mediated induction of heme oxygenase-1 in hepatoma cells. Role of mitogen-activated protein kinases.
Q32086751Molecular cloning, characterization, and expression of the chicken heme oxygenase-1 gene in transfected primary cultures of chick embryo liver cells
Q77932184Nitric oxide mediates the lipopolysaccharide dependent upregulation of the heme oxygenase-1 gene expression in cultured rat Kupffer cells
Q47792797Reduction in porphyrin excretion as a sensitive indicator of lead toxicity in primary cultures of adult rat hepatocytes
Q42548667Regulation of expression of the human heme oxygenase-1 gene in transfected chick embryo liver cell cultures
Q92454668Role of aminolevulinic acid synthase 1 in doxorubicin-induced oxidative stress to the ardiomyocyte
Q73237076The Porphyrias
Q41745490The biochemistry of heme synthesis in porphyria and in the porphyrinurias
Q31427884Upstream regulatory elements in chick heme oxygenase-1 promoter: a study in primary cultures of chick embryo liver cells

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