Antipsychotic metabolic effects: weight gain, diabetes mellitus, and lipid abnormalities

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Antipsychotic metabolic effects: weight gain, diabetes mellitus, and lipid abnormalities is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1177/070674370104600308
P698PubMed publication ID11320682

P2093author name stringS M McCann
S H Kennedy
R S McIntyre
P2860cites workThe relationship between blood prolactin levels and risk of breast cancer in premenopausal womenQ57658869
Ketoacidosis as a side-effect of clozapine: a case reportQ59221805
Body Weight and Mortality among WomenQ22250911
Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptorsQ28119146
m-Chlorophenylpiperazine decreases food intake in a test mealQ28307494
Congenital leptin deficiency is associated with severe early-onset obesity in humansQ29618702
Neuroleptic-induced hyperprolactinemiaQ33586375
Weight gain: side effect of atypical neuroleptics?Q33707031
Effects of recombinant leptin therapy in a child with congenital leptin deficiency.Q33874084
Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networksQ34301257
Weight gain among schizophrenic patients treated with clozapineQ35254182
Neuronal lipopigment: a marker for cognitive impairment and long-term effects of psychotropic drugsQ35933865
Metabolic fuels and reproduction in female mammalsQ36321920
Weight gain associated with neuroleptic medication: a reviewQ40371451
Clozapine in bipolar disorder: treatment implications for other atypical antipsychoticsQ40851029
Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and alpha 1-adrenergic receptors in vitroQ40956761
Weight changes with depot neuroleptic maintenance therapyQ41717291
Hypothalamic sites affecting masticatory neurons in ratsQ42470397
Insulin binding and action on adipocytes from female rats with experimentally induced chronic hyperprolactinemiaQ42510636
Systemic sulpiride increases dopamine metabolites in the lateral hypothalamusQ43699831
Sulpiride injections in the lateral hypothalamus induce feeding and drinking in ratsQ44729201
Clozapine-induced weight gain: prevalence and clinical relevanceQ45169845
Long term administration of some antipsychotic drugs increases body weight and feeding in rats. Are D2 dopamine receptors involved?Q47194368
Clozapine, diabetes mellitus, weight gain, and lipid abnormalities: A five-year naturalistic studyQ47238068
Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trialQ47254016
Prevalence of attempting weight loss and strategies for controlling weightQ47255320
Serum leptin changes in epileptic patients who gain weight after therapy with valproic acidQ47261398
Mood stabilization and weight loss with topiramateQ47263744
Weight gain in adolescents treated with risperidone and conventional antipsychotics over six monthsQ47274430
Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restorationQ47305899
Weight reduction in schizophrenics by molindoneQ47331051
Differential effect of clozapine on weight: a controlled studyQ47331289
Weight Changes With Schizophrenic Psychosis and Psychotropic Drug TherapyQ47386655
Use of topiramate, a new anti-epileptic as a mood stabilizerQ48777380
Yohimbine impairs P50 auditory sensory gating in normal subjects.Q50524442
Evidence for involvement of 5-HT1C and 5-HT2 receptors in the food intake suppressant effects of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)Q52046642
A clinical trial of the efficacy and acceptability of D-fenfluramine in the treatment of neuroleptic-induced obesity.Q52069574
Too many chronic mentally disabled patients are too fat.Q52081902
Recent advances in basic obesity research.Q52173371
Double-blind comparison of olanzapine versus risperidone in the treatment of schizophrenia and other psychotic disorders.Q53589905
Molindone in chronic schizophrenia.Q54192063
Serum leptin levels increase rapidly after initiation of clozapine therapyQ57338243
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectweight gainQ3403879
P304page(s)273-281
P577publication date2001-04-01
P1433published inCanadian Journal of PsychiatryQ5030253
P1476titleAntipsychotic metabolic effects: weight gain, diabetes mellitus, and lipid abnormalities
P478volume46

Reverse relations

cites work (P2860)
Q46766527A crossover study on lipid and weight changes associated with olanzapine and risperidone
Q43832862A dose-ranging exploratory study of the effects of ethyl-eicosapentaenoate in patients with persistent schizophrenic symptoms
Q48247071A placebo-controlled, double-blind study of the efficacy and safety of aripiprazole for the treatment of acute manic or mixed episodes in Asian patients with bipolar I disorder (the AMAZE study).
Q46070377Acute effects of olanzapine on behavioural expression including the behavioural satiety sequence in female rats
Q27323282Acute peripheral but not central administration of olanzapine induces hyperglycemia associated with hepatic and extra-hepatic insulin resistance
Q35693269Adverse metabolic effects associated with atypical antipsychotics: literature review and clinical implications
Q34661499Almost all antipsychotics result in weight gain: a meta-analysis
Q37725872Alterations of Lipid-Lipoprotein and Leptin in Bipolar Disorder Associated with Clinic Process.
Q42864443Antipsychotic drugs and diabetes.
Q35826319Antipsychotic polypharmacy in patients with schizophrenia: a multicentre comparative study in East Asia
Q48258866Aripiprazole in combination with lamotrigine for the long-term treatment of patients with bipolar I disorder (manic or mixed): a randomized, multicenter, double-blind study (CN138-392).
Q61458788Assessing metabolic syndrome in people with ID (intellectual disabilities) on antipsychotic medication
Q46561251Assessment of metabolic impairments inducted by atypical antipsychotics among schizophrenic patients
Q35793345Atypical antipsychotics and diabetes mellitus
Q36205791Atypical antipsychotics in primary generalized anxiety disorder or comorbid with mood disorders.
Q36302677Atypical antipsychotics in psychiatric practice: practical implications for clinical monitoring
Q35133099Atypical psychotropic medications and their adverse effects: a review for the African-American primary care physician.
Q35212362Behavioural management of antipsychotic-induced weight gain: a review
Q41118477Blood lactate levels as a biomarker of antipsychotic side effects in patients with schizophrenia
Q35100107Body mass index and metabolic parameters in patients with schizophrenia during long-term treatment with paliperidone palmitate
Q38050714Bridging the gap from evidence to policy and practice: reducing the progression to metabolic syndrome for children and adolescents on antipsychotic medication
Q28728401Changes in body weight and psychotropic drugs: a systematic synthesis of the literature
Q44263522Characterization of olanzapine-induced weight gain in rats
Q51185707Chronic administration of olanzapine induces metabolic and food intake alterations: a mouse model of the atypical antipsychotic-associated adverse effects.
Q50124634Combined treatment with a selective PDE10A inhibitor TAK-063 and either haloperidol or olanzapine at subeffective doses produces potent antipsychotic-like effects without affecting plasma prolactin levels and cataleptic responses in rodents
Q35918173Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells
Q50778364Deterioration of metabolic parameters during short-term psychiatric inpatient treatment: a prospective naturalistic study.
Q46735466Early effects of olanzapine on serum levels of ghrelin, adiponectin and leptin in patients with schizophrenia
Q44418817Effect of Acute Psychotic Stress in Nondiabetic Subjects on β-Cell Function and Insulin Sensitivity
Q37257633Effectiveness of a psychosocial weight management program for individuals with schizophrenia
Q44622757Effects of olanzapine on lipid abnormalities in elderly psychotic patients
Q47554150Effects of primary care clinician beliefs and perceived organizational facilitators on the delivery of preventive care to individuals with mental illnesses.
Q48310435Efficacy of aripiprazole adjunctive to lithium or valproate in the long-term treatment of patients with bipolar I disorder with an inadequate response to lithium or valproate monotherapy: a multicenter, double-blind, randomized study
Q50096809Exploring the Relationship Between Body Mass Index and Positive Symptom Severity in Persons at Clinical High Risk for Psychosis
Q47201475Functional Changes of Orexinergic Reaction to Psychoactive Substances.
Q33964839H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs.
Q37147674Identification of a butyrophenone analog as a potential atypical antipsychotic agent: 4-[4-(4-chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluorophenyl)butan-1-one
Q90860747Increased risk of type 2 diabetes among the siblings of patients with schizophrenia
Q33721019Inflammation: opportunities for treatment stratification among individuals diagnosed with mood disorders
Q51901947Influence of medication choice and comorbid diabetes: the cost of bipolar disorder in a privately insured US population.
Q48404127Insights into the structure and function of 5-HT(2) family serotonin receptors reveal novel strategies for therapeutic target development
Q36377890Interventions to Address Medical Conditions and Health-Risk Behaviors Among Persons With Serious Mental Illness: A Comprehensive Review
Q36033305Intramuscular olanzapine: a review of its use in the management of acute agitation
Q88687824Iron overload prevents oxidative damage to rat brain after chlorpromazine administration
Q44858920Management of diabetes mellitus occurring during treatment with olanzapine: report of six cases and clinical implications
Q36258561Metabolic side effects of atypical antipsychotics in children: a literature review
Q88808771Metabolic side effects of atypical antipsychotics in older adults
Q37821806Mood disorders and obesity: understanding inflammation as a pathophysiological nexus
Q44202981New-onset diabetes and ketoacidosis with atypical antipsychotics
Q47305725No effect of dietary fat on short-term weight gain in mice treated with atypical antipsychotic drugs
Q38163397Paliperidone extended-release: safety and tolerability from a metabolic profile perspective
Q77597822Pharmacoepidemiology and drug safety
Q80312477Pharmacogenetics of antipsychotic-induced weight gain
Q35548146Pharmacotherapy to limit weight gain caused by antipsychotic use
Q36832356Phentermine, sibutramine and affective disorders.
Q79102815Position of the American Dietetic Association: Integration of medical nutrition therapy and pharmacotherapy
Q42172035Possible association of QTc interval prolongation with co-administration of quetiapine and lovastatin
Q33519730Predictors of metabolic monitoring among schizophrenia patients with a new episode of second-generation antipsychotic use in the Veterans Health Administration
Q40836016Prevalence of Antidiabetic and Antilipidemic Medications in Children and Adolescents Treated With Atypical Antipsychotics in a Virginia Medicaid Population
Q37479172Psychiatric treatment: A risk factor for obesity?
Q36836820Relationship between obesity and antipsychotic drug use in the adult population: a longitudinal, retrospective claim database study in Primary Care settings
Q45053023Rhabdomyolysis and compartment syndrome with coadministration of risperidone and simvastatin
Q39675765Risperidone (Risperdal): increased rate of cerebrovascular events in dementia trials.
Q35612445Risperidone in acute and long-term therapy of schizophrenia--a clinical profile
Q45147293Schizophrenia, diabetes mellitus and antipsychotics
Q39353717Second-Generation Antipsychotics and Metabolic Side Effects: A Systematic Review of Population-Based Studies
Q37958894Structural contributions of antipsychotic drugs to their therapeutic profiles and metabolic side effects
Q79303671The Effect of Antipsychotics on Plasma Lipids
Q38777526The impact of weight gain associated with atypical antipsychotic use in schizophrenia
Q37155311The prevalence of metabolic syndrome in schizophrenic patients using antipsychotics
Q44103185Topiramate versus bupropion SR when added to mood stabilizer therapy for the depressive phase of bipolar disorder: a preliminary single-blind study
Q34550254Treating bipolar disorder. Evidence-based guidelines for family medicine
Q35673093Treatment of acute mania
Q33861601Treatment-resistant depression in primary care across Canada
Q35102481Understanding the new and evolving profile of adverse drug effects in schizophrenia
Q35692834Use of psychopharmacologic agents in the elderly.
Q51537591Valproate, bipolar disorder and polycystic ovarian syndrome.
Q44612816WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics
Q44602396Weight Change after an Atypical Antipsychotic Switch
Q35669815Weight gain associated with atypical antipsychotic use in children and adolescents: prevalence, clinical relevance, and management
Q36230583Weight gain, schizophrenia and antipsychotics: new findings from animal model and pharmacogenomic studies
Q89037507Which components of specialized early intervention for psychosis do senior providers see as most important?
Q81442160[How much general medical competency does a psychiatrist need?]

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