Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders

scientific article published on 15 September 2014

Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.20140039
P932PMC publication ID4172212
P698PubMed publication ID25225461
P5875ResearchGate publication ID267099319

P50authorChristine LacabaratzQ56807941
Denis ComteQ56998214
Giuseppe PantaleoQ88061163
Thierry RogerQ40228404
P2093author name stringYves Levy
Pierre-Alexandre Bart
Matthieu Perreau
Céline Pellaton
Florence Bellanger
Selena Vigano
Guillaume Buss
P2860cites workCD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tractQ22242965
CD20 deficiency in humans results in impaired T cell-independent antibody responsesQ24653638
Two subsets of memory T lymphocytes with distinct homing potentials and effector functionsQ28146072
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiencyQ28208331
An antibody-deficiency syndrome due to mutations in the CD19 geneQ28238166
TACI is mutant in common variable immunodeficiency and IgA deficiencyQ28260786
Restoring function in exhausted CD8 T cells during chronic viral infectionQ28289222
Skewed maturation of memory HIV-specific CD8 T lymphocytesQ45284555
The T cell response to persistent herpes virus infections in common variable immunodeficiencyQ45411294
Modulation of human memory T-cell function by different antigen-presenting cells.Q50979578
Hypogammaglobulinaemia: cumulative experience in 49 patients in a tertiary care institution.Q51708165
The EUROclass trial: defining subgroups in common variable immunodeficiency.Q51971194
Unravelling the complexity of T cell abnormalities in common variable immunodeficiency.Q51977256
Impaired antibody affinity maturation process characterizes a subset of patients with common variable immunodeficiency.Q52023797
IL 2 restores memory B cell activation by antigen-specific T cell clone variants.Q52204244
Common variable immunodeficiency: clinical and immunological features of 248 patients.Q53546018
Immunodeficiency associated with loss of T4+ inducer T-cell functionQ70542064
Passive protection of lambs against enteropathogenic Escherichia coli: role of antibodies in serum and colostrum of dams vaccinated with K99 antigenQ72136868
Serum proteins in human squamous epitheliumQ72139276
Elevated serum levels of interleukin-4 and interleukin-6 in patients with common variable immunodeficiency (CVI) are associated with chronic immune activation and low numbers of CD4+ lymphocytesQ72668304
Functional 'immaturity' of isolated B cells from patients with hypogammaglobulinaemiaQ72886458
Long-term low-dose IL-2 enhances immune function in common variable immunodeficiencyQ74243224
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progressionQ29618956
CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiencyQ33755327
Proliferation capacity and cytotoxic activity are mediated by functionally and phenotypically distinct virus-specific CD8 T cells defined by interleukin-7R{alpha} (CD127) and perforin expressionQ33769360
How I treat common variable immune deficiencyQ33997226
Passive immunization against Pseudomonas with a ribosomal vaccine-induced immune serum and immunoglobulin fractionsQ34079110
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defenseQ34087551
Common variable immunodeficiency is associated with defective functions of dendritic cellsQ34330097
T cell-dependent B cell activationQ34363600
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicityQ34364103
Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and ImmunologyQ34507918
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunctionQ34570127
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infectionQ34570624
HIV infection and the gastrointestinal immune systemQ34601874
Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretionQ34615273
SPICE: exploration and analysis of post-cytometric complex multivariate datasetsQ34769778
Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infectionQ35001605
IVIg immune reconstitution treatment alleviates the state of persistent immune activation and suppressed CD4 T cell counts in CVID.Q35018213
Isolation of viable antigen-specific CD8+ T cells based on membrane-bound tumor necrosis factor (TNF)-α expressionQ35048086
DNA/NYVAC vaccine regimen induces HIV-specific CD4 and CD8 T-cell responses in intestinal mucosa.Q35382338
Antigen-specific memory B cell developmentQ36072438
Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activityQ36348121
Defect in IgV gene somatic hypermutation in common variable immuno-deficiency syndromeQ36639355
Dysregulated CD1 profile in myeloid dendritic cells in CVID is normalized by IVIg treatment.Q36928356
Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.Q36959840
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4.Q37114768
Common variable immunodeficiency: a new look at an old disease.Q37240590
Immunosenescence and HIV.Q38015598
The human gastrointestinal secretory immune system in health and diseaseQ39840062
Lymphocyte Mediators and Cellular HypersensitivityQ39921997
Macrophages and delayed-type hypersensitivityQ39989347
Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligandQ42767299
Secretory and humoral immunologic response of atopic and non-atopic individuals to intranasally administered antigenQ43524704
Abnormalities of lymphokine gene expression in patients with common variable immunodeficiency.Q43536448
Impaired pneumovax-23-induced monocyte-derived cytokine production in patients with common variable immunodeficiencyQ43737162
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcommon variable immunodeficiencyQ1472818
P304page(s)2033-2045
P577publication date2014-09-15
P1433published inJournal of Experimental MedicineQ3186912
P1476titleExhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders
P478volume211