N-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression

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N-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9j8317L
P356DOI10.1371/JOURNAL.PONE.0108317
P932PMC publication ID4172727
P698PubMed publication ID25248126
P5875ResearchGate publication ID266027071

P2093author name stringJui-Chen Tsai
Ying-Jan Wang
Yu-Hsuan Lee
Chia-Ho Lin
Chien-Cheng Huang
Shih-Bin Su
Hamm-Ming Sheu
Bour-Jr Wang
P2860cites workHypervalent chromium mimics reactive oxygen species as measured by the oxidant-sensitive dyes 2',7'-dichlorofluorescin and dihydrorhodamineQ77709659
[Autophagy and immune response]Q95496286
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysQ25939005
Apoptotic cell clearance: basic biology and therapeutic potential.Q26825935
Antioxidant enzymes and human diseasesQ28142812
Nuclear factor-kappaB-dependent induction of interleukin-8 gene expression by tumor necrosis factor alpha: evidence for an antioxidant sensitive activating pathway distinct from nuclear translocationQ28143935
Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signalingQ28387227
Autophagy in infection, inflammation, and immunityQ29248363
Autophagy and the Integrated Stress ResponseQ29547398
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell lineQ29547520
How to interpret LC3 immunoblottingQ29614175
Advances in metal-induced oxidative stress and human diseaseQ29615581
A novel response of cancer cells to radiation involves autophagy and formation of acidic vesiclesQ32046208
Can antioxidant vitamins materially reduce oxidative damage in humans?Q33610725
Apoptosis in cancerQ33846227
Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin diseaseQ33915587
Programmed cell death (PCD). Apoptosis, autophagic PCD, or others?Q33934181
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicityQ33948462
Molecular mechanisms of apoptosis induced by cytotoxic chemicalsQ34072607
The chemistry and biological activities of N-acetylcysteineQ34341263
Oxidative stress in the pathogenesis of skin diseaseQ34582038
The inflammatory response to cell deathQ34718276
Molecular mechanisms of N-acetylcysteine actionsQ35076338
Targeting programmed cell death in neurodegenerative diseasesQ35120138
Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactionsQ36229956
Keratinocyte apoptosis in epidermal development and diseaseQ36371190
Toxicity and carcinogenicity of chromium compounds in humansQ36493576
Autophagy and IL-1 Family CytokinesQ36742485
Early molecular events in the induction phase of contact sensitivityQ36837916
Dermatological toxicity of hexavalent chromiumQ36871053
Expansion and evolution of cell death programmesQ37139298
Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy developmentQ37295309
Role of direct reactivity with metals in chemoprotection by N-acetylcysteine against chromium(VI), cadmium(II), and cobalt(II).Q37296815
Targeting innate immunity protein kinase signalling in inflammationQ37502685
Autophagy signaling through reactive oxygen species.Q37793161
Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosisQ38094613
Apoptotic and necroptotic cell death in cutaneous inflammationQ38097246
Investigating the role of reactive oxygen species in regulating autophagy.Q38121268
JunB forms the majority of the AP-1 complex and is a target for redox regulation by receptor tyrosine kinase and G protein-coupled receptor agonists in smooth muscle cellsQ38327919
Activation of autophagy protects against ROS-mediated mitochondria-dependent apoptosis in L-02 hepatocytes induced by Cr(VI).Q39014165
Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticlesQ39440577
Hexavalent chromium induced ROS formation, Akt, NF-kappaB, and MAPK activation, and TNF-alpha and IL-1alpha production in keratinocytes.Q39682219
Combination treatment with arsenic trioxide and irradiation enhances cell-killing effects in human fibrosarcoma cells in vitro and in vivo through induction of both autophagy and apoptosisQ39732599
Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine fibrosarcoma L929 cellsQ39888530
TNF-alpha stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytesQ39971896
Vitamin K2 induces autophagy and apoptosis simultaneously in leukemia cellsQ39997033
Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations.Q40397791
Antioxidant and redox regulation of gene transcriptionQ40989720
Antioxidants, redox-regulated transcription factors, and inflammationQ41191889
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generationQ41635173
Nickel induces oxidative burst, NF-κB activation and interleukin-8 production in human neutrophilsQ42969863
N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species.Q43180443
Development of a concomitant nickel and chromium sensitization model in the guinea pig.Q43435920
Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.Q44427360
Effect of age on antioxidants and molecular markers of oxidative damage in murine epidermis and dermisQ46102116
Allergic contact dermatitis to metal allergens in Iran.Q46131124
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectacetylcysteineQ375613
cell deathQ2383867
hexavalent chromiumQ2660666
P304page(s)e108317
P577publication date2014-09-23
P1433published inPLOS OneQ564954
P1476titleN-acetylcysteine attenuates hexavalent chromium-induced hypersensitivity through inhibition of cell death, ROS-related signaling and cytokine expression
P478volume9

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cites work (P2860)
Q36011551Advanced oxidative protein products induced human keratinocyte apoptosis through the NOX-MAPK pathway
Q41476700Carcinogenicity of chromium and chemoprevention: a brief update
Q38536207Chromium allergy and dermatitis: prevalence and main findings
Q36534051Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition
Q46550195Environmental Presence of Hexavalent but Not Trivalent Chromium Causes Neurotoxicity in Exposed Drosophila melanogaster
Q38836465Hexavalent chromium induces apoptosis in male somatic and spermatogonial stem cells via redox imbalance
Q39414548Immunological, chemical and clinical aspects of exposure to mixtures of contact allergens
Q51303097N-Acetyl-L-Cysteine Protects Liver and Kidney Against Chromium(VI)-Induced Oxidative Stress in Mice.
Q38723859N-acetylcysteine Attenuates Cobalt Nanoparticle-Induced Cytotoxic Effects through Inhibition of Cell Death, Reactive Oxygen Species-related Signaling and Cytokines Expression.
Q52360003N-acetylcysteine and vitamin E rescue animal longevity and cellular oxidative stress in pre-clinical models of mitochondrial complex I disease.
Q60935435Pterostilbene Attenuates Hexavalent Chromium-Induced Allergic Contact Dermatitis by Preventing Cell Apoptosis and Inhibiting IL-1β-Related NLRP3 Inflammasome Activation
Q64118773The Potential Role of the NLRP3 Inflammasome Activation as a Link Between Mitochondria ROS Generation and Neuroinflammation in Postoperative Cognitive Dysfunction
Q37744128The Protective Role of Hyaluronic Acid in Cr(VI)-Induced Oxidative Damage in Corneal Epithelial Cells.
Q28073646The Roles of Autophagy and the Inflammasome during Environmental Stress-Triggered Skin Inflammation
Q26748610The signaling involving in autophagy machinery in keratinocytes and therapeutic approaches for skin diseases

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