scholarly article | Q13442814 |
P50 | author | Ana M Gomez | Q84759810 |
Luc Ver Donck | Q43116238 | ||
Marcel van der Heyden | Q70859936 | ||
P2093 | author name string | S Richard | |
L Belardinelli | |||
A M Gomez | |||
M A Vos | |||
S Rajamani | |||
G Antoons | |||
P Oosterhoff | |||
A Oros | |||
J D Beekman | |||
M J Houtman | |||
N J Attevelt | |||
P Neco | |||
P2860 | cites work | Enhanced Ca(2+) release and Na/Ca exchange activity in hypertrophied canine ventricular myocytes: potential link between contractile adaptation and arrhythmogenesis | Q73108727 |
Contractile adaptations preserving cardiac output predispose the hypertrophied canine heart to delayed afterdepolarization-dependent ventricular arrhythmias | Q73108734 | ||
Similarities between early and delayed afterdepolarizations induced by isoproterenol in canine ventricular myocytes | Q73471651 | ||
Cellular basis of biventricular hypertrophy and arrhythmogenesis in dogs with chronic complete atrioventricular block and acquired torsade de pointes | Q77296607 | ||
Acceleration-induced action potential prolongation and early afterdepolarizations | Q77456110 | ||
KN-93, an inhibitor of multifunctional Ca++/calmodulin-dependent protein kinase, decreases early afterdepolarizations in rabbit heart | Q77721137 | ||
Window Ca2+ current and its modulation by Ca2+ release in hypertrophied cardiac myocytes from dogs with chronic atrioventricular block | Q79397000 | ||
Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study | Q80401265 | ||
In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome | Q80721442 | ||
Use of the rabbit with a failing heart to test for torsadogenicity | Q81763629 | ||
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches | Q22337395 | ||
Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action | Q24671796 | ||
Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia | Q28201561 | ||
Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2 | Q28751737 | ||
Frequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells. | Q31119358 | ||
Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia | Q33551271 | ||
Flunarizine is a highly potent inhibitor of cardiac hERG potassium current | Q34497041 | ||
Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle | Q34545690 | ||
Assessing predictors of drug-induced torsade de pointes. | Q35599835 | ||
The effects of calcium antagonists on calcium overload contractures in embryonic chick myocytes induced by ouabain and veratrine. | Q35756457 | ||
Assessing the proarrhythmic potential of drugs: current status of models and surrogate parameters of torsades de pointes arrhythmias. | Q36484035 | ||
The canine model with chronic, complete atrio-ventricular block | Q37178070 | ||
Calcium channels: molecular pharmacology, structure and regulation | Q39471173 | ||
Mechanism of block and identification of the verapamil binding domain to HERG potassium channels | Q40954779 | ||
Protective activity of calcium entry blockers against ouabain intoxication in anesthetized guinea pigs | Q41247242 | ||
A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644. | Q41251946 | ||
Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome | Q42276757 | ||
The effect of flunarizine and ryanodine on acquired torsades de pointes arrhythmias in the intact canine heart | Q42277143 | ||
Late na(+) current inhibition by ranolazine reduces torsades de pointes in the chronic atrioventricular block dog model | Q43156268 | ||
Flunarizine allows differentiation between mechanisms of arrhythmias in the intact heart | Q43473271 | ||
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness | Q43633756 | ||
The relationship of clinical QT prolongation to outcome in the conscious dog using a beat-to-beat QT-RR interval assessment | Q44072285 | ||
Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs | Q45101334 | ||
Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil | Q45226112 | ||
An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes | Q46725746 | ||
L-type calcium current recovery versus ventricular repolarization: preserved membrane-stabilizing mechanism for different QT intervals across species | Q46869578 | ||
Proarrhythmic electrical remodelling is associated with increased beat-to-beat variability of repolarisation | Q48632971 | ||
Atrial-specific drug AVE0118 is free of torsades de pointes in anesthetized dogs with chronic complete atrioventricular block | Q48648018 | ||
Flunarizine inhibits a high-threshold inactivating calcium channel (N-type) in isolated hippocampal neurons | Q48721093 | ||
Effects of tetrodotoxin, lidocaine, verapamil, and AHR-2666 on Ouabain-induced delayed afterdepolarizations in canine Purkinje fibers. | Q51878433 | ||
Mechanism of L- and T-type Ca2+ channel blockade by flunarizine in ventricular myocytes of the guinea-pig. | Q53992653 | ||
Guide to Receptors and Channels (GRAC), 4th Edition | Q56639335 | ||
Further observations to confirm the arrhythmia mechanism-specific effects of flunarizine | Q67899305 | ||
Suppression of Torsades de Pointes with verapamil in patients with atrio-ventricular block | Q67947029 | ||
Mechanisms underlying early and delayed afterdepolarizations induced by catecholamines | Q68465482 | ||
Differentiation of calcium entry blockers into calcium channel blockers and calcium overload blockers | Q69617256 | ||
Combined potassium and calcium channel blocking activities as a basis for antiarrhythmic efficacy with low proarrhythmic risk: experimental profile of BRL-32872 | Q71082649 | ||
The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns | Q71468970 | ||
Rhythm anomalies related to delayed repolarization in vivo: influence of sarcolemmal Ca++ entry and intracellular Ca++ overload | Q71658788 | ||
Sudden cardiac death in heart failure. The role of abnormal repolarization | Q72791800 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | verapamil | Q410291 |
P304 | page(s) | 162-175 | |
P577 | publication date | 2010-09-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Robust anti-arrhythmic efficacy of verapamil and flunarizine against dofetilide-induced TdP arrhythmias is based upon a shared and a different mode of action | |
P478 | volume | 161 |
Q52910995 | Calcium release near L-type calcium channels promotes beat-to-beat variability in ventricular myocytes from the chronic AV block dog. |
Q48422544 | Can the addition of verapamil to bedaquiline-containing regimens improve tuberculosis treatment outcomes? A novel approach to optimizing TB treatment |
Q51034289 | Efficient and specific cardiac IK₁ inhibition by a new pentamidine analogue. |
Q41351531 | Ions, equations and electrons: the evolving role of computer simulations in cardiac electrophysiology safety evaluations |
Q46562591 | Negative electro-mechanical windows are required for drug-induced Torsades de Pointes in the anesthetized guinea pig. |
Q38415718 | Republished: A straightforward guide to the basic science behind arrhythmogenesis |
Q33635283 | Risk of QT prolongation and torsade de pointes associated with exposure to hydroxyzine: re-evaluation of an established drug |
Q39434566 | Role of abnormal repolarization in the mechanism of cardiac arrhythmia |
Q54954354 | Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia. |
Q40920761 | Short-term variability in QT interval and ventricular arrhythmias induced by dofetilide are dependent on high-frequency autonomic oscillations. |
Q30491333 | Short-term variability of repolarization is superior to other repolarization parameters in the evaluation of diverse antiarrhythmic interventions in the chronic AV block dog. |
Q90427830 | The Increment of Short-term Variability of Repolarisation Determines the Severity of the Imminent Arrhythmic Outcome |
Q37671300 | The electromechanical window is no better than QT prolongation to assess risk of Torsade de Pointes in the complete atrioventricular block model in dogs |
Q36506873 | The high frequency relationship: implications for torsadogenic hERG blockers |
Q41767035 | Verapamil as an antiarrhythmic agent in congestive heart failure: hopping from rabbit to human? |
Q34923159 | Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model |
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