A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures

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A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1032973741
P356DOI10.1038/MP.2011.165
P932PMC publication ID3317062
P698PubMed publication ID22143005
P5875ResearchGate publication ID51854125

P2093author name stringD A Rossignol
R E Frye
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Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: part B - behavioral resultsQ21254631
Safety and efficacy of oral DMSA therapy for children with autism spectrum disorders: Part A--medical resultsQ21254632
Hyperbaric treatment for children with autism: a multicenter, randomized, double-blind, controlled trialQ21260340
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Genetics evaluation for the etiologic diagnosis of autism spectrum disordersQ22242734
Maternal residence near agricultural pesticide applications and autism spectrum disorders among children in the California Central ValleyQ24569536
Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticidesQ24602033
Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysisQ24630557
From inflammation to sickness and depression: when the immune system subjugates the brainQ24633527
Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. childrenQ24676300
Microglia and neuroinflammation: a pathological perspectiveQ24799838
Prenatal lead exposure, delta-aminolevulinic acid, and schizophreniaQ24811775
The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot studyQ27496706
Oxidative stress in hypertensionQ28217587
Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot studyQ28219023
A preliminary trial of ascorbic acid as supplemental therapy for autismQ28257201
Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stressQ28257571
Oxidative stress in psychiatric disorders: evidence base and therapeutic implicationsQ28265319
Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, United States, 2006Q28268208
Developmental neurotoxicity of industrial chemicalsQ28279457
Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay areaQ28391198
Response of arsenic-induced oxidative stress, DNA damage, and metal imbalance to combined administration of DMSA and monoisoamyl-DMSA during chronic arsenic poisoning in ratsQ28564453
Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergenceQ29618819
ortho-substituted PCB95 alters intracellular calcium signaling and causes cellular acidification in PC12 cells by an immunophilin-dependent mechanismQ32034830
Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell functionQ33273613
Low blood lead levels associated with clinically diagnosed attention-deficit/hyperactivity disorder and mediated by weak cognitive controlQ33639446
Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patientsQ33751063
Mercury induces inflammatory mediator release from human mast cellsQ33774385
Role of oxidative stress in cardiovascular diseasesQ33953686
Immunity, neuroglia and neuroinflammation in autismQ33992778
A comprehensive approach to treating autism and attention-deficit hyperactivity disorder: a prepilot studyQ34009133
Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children anQ34010535
Increased oxidative stress and DNA damage in bipolar disorder: A twin-case reportQ60417993
Ultrastructural and biochemical changes in renal mitochondria during chronic oral methyl mercury exposure: the relationship to renal functionQ67712269
Effects of pesticides on isolated rat hepatocytes, mitochondria, and microsomes IIQ72157994
Arsenic-induced oxidative stress and its reversibility following combined administration of N-acetylcysteine and meso 2,3-dimercaptosuccinic acid in ratsQ73182888
Induction of apoptosis in human T-cells by methyl mercury: temporal relationship between mitochondrial dysfunction and loss of reductive reserveQ77754442
Oxidative stress in autismQ83965328
Toxicity biomarkers in autism spectrum disorder: a blinded study of urinary porphyrinsQ84564595
Mercury and nickel allergy: risk factors in fatigue and autoimmunityQ34084431
Immunological treatments for autismQ34094304
Mitochondrial dysfunction and pathology in bipolar disorder and schizophreniaQ34137363
Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcomeQ34348399
Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollutionQ34363063
Low-dose naltrexone effects on plasma chemistries and clinical symptoms in autism: a double-blind, placebo-controlled study.Q34372384
Dialysable lymphocyte extract (DLyE) in infantile onset autism: a pilot studyQ34413137
Proximity to point sources of environmental mercury release as a predictor of autism prevalenceQ34589563
Biomarker-guided interventions of clinically relevant conditions associated with autism spectrum disorders and attention deficit hyperactivity disorder.Q34618405
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Autism spectrum disorders: concurrent clinical disordersQ34721379
Psychiatric disorders among Egyptian pesticide applicators and formulators.Q34743069
Biomarkers of environmental toxicity and susceptibility in autismQ34837538
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autismQ34895200
The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disordersQ34961345
Neuroinflammation in Alzheimer's disease and prion disease.Q34963776
Mitochondrial involvement in psychiatric disordersQ34994220
Schizophrenia and oxidative stress: glutamate cysteine ligase modifier as a susceptibility geneQ35015897
Diabetes, oxidative stress, and antioxidants: a reviewQ35077717
Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brainsQ35153945
Mitochondrial dysfunction can connect the diverse medical symptoms associated with autism spectrum disordersQ35232104
Neurodegenerative diseases and oxidative stressQ35636137
Organic mercury compounds and autoimmunityQ36180065
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autismQ37029453
Oxidative stress markers in bipolar disorder: a meta-analysisQ37186196
Nitrative and oxidative stress in toxicology and diseaseQ37402818
Elevated immune response in the brain of autistic patientsQ37405256
Mechanistic biomarkers for autism treatmentQ37556922
Improving the prediction of response to therapy in autismQ37774095
The role of mitochondrial dysfunction in psychiatric diseaseQ37785512
Mitochondrial DNA (mtDNA) and schizophreniaQ37803459
Practical guidelines for evaluating lead exposure in children with mental health conditions: molecular effects and clinical implicationsQ37835625
Metabolic biomarkers related to energy metabolism in Saudi autistic children.Q39986451
Aluminum-induced mitochondrial dysfunction leads to lipid accumulation in human hepatocytes: a link to obesity.Q40086768
Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages.Q40918316
Pentoxifylline: brief review and rationale for its possible use in the treatment of autismQ41446639
Toxic and essential metal interactionsQ41548484
Cerebrospinal fluid biopterin and biogenic amine metabolites during oral R-THBP therapy for infantile autismQ42276076
Opioid-immune interactions in autism: behavioural and immunological assessment during a double-blind treatment with naltrexoneQ42551219
Pilot study of the effect of methyl B12 treatment on behavioral and biomarker measures in children with autismQ42673710
Neuroinflammation in schizophrenia-related psychosis: a PET study.Q43259552
Double-blind placebo-controlled trial of pentoxifylline added to risperidone: effects on aberrant behavior in children with autism.Q43272958
Hepatocyte lysis induced by environmental metal toxins may involve apoptotic death signals initiated by mitochondrial injuryQ43838528
Antioxidant enzyme activities and oxidative stress in affective disordersQ44838705
Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats.Q45157215
Dysregulated immune system in children with autism: beneficial effects of intravenous immune globulin on autistic characteristicsQ45175335
Metabolic biomarkers related to oxidative stress and antioxidant status in Saudi autistic childrenQ46078486
Oxidative stress in neurotoxic effects of methylmercury poisoning.Q46176787
The recovery of a child with autism spectrum disorder through biomedical interventions.Q46222105
A prospective study of transsulfuration biomarkers in autistic disordersQ46494129
A prospective study of mercury toxicity biomarkers in autistic spectrum disordersQ46988646
Mitochondrial DNA deletion mutations in patients with neuropsychiatric symptomsQ48942369
Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disordersQ50302140
Response to steroid therapy in autism secondary to autoimmune lymphoproliferative syndromeQ50312944
Treatment of children with autism with intravenous immunoglobulinQ50313961
Case study: corticosteroid treatment of language regression in pervasive developmental disorder.Q52207067
Neuroinflammation in Alzheimer's disease and major depression.Q53409265
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecthazardous substancesQ757138
mitochondrial diseaseQ935710
autism spectrum disorderQ1436063
pervasive developmental disorderQ6691991
immune disorderQ3843811
publishingQ3972943
autismQ38404
research trendQ60617927
physiological phenomenonQ66615932
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)389-401
P577publication date2011-12-06
2012-04-01
P1433published inMolecular PsychiatryQ6895973
P1476titleA review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures
P478volume17

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