Nuclear localized Influenza nucleoprotein N-terminal deletion mutant is deficient in functional vRNP formation

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Nuclear localized Influenza nucleoprotein N-terminal deletion mutant is deficient in functional vRNP formation is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1004936164
P356DOI10.1186/1743-422X-11-155
P932PMC publication ID4177073
P698PubMed publication ID25174360

P2093author name stringLaura L Newcomb
Jose Ramirez
Christian F Guerrero-Juarez
Abel Sanchez
P2860cites workIdentification of RNA helicase A as a cellular factor that interacts with influenza A virus NS1 protein and its role in the virus life cycleQ35826575
Influenza virus NS1 protein enhances the rate of translation initiation of viral mRNAsQ35837862
Characterization of the polyadenylation signal of influenza virus RNAQ36627863
Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 proteinQ37093452
Influenza a virus polymerase is an integral component of the CPSF30-NS1A protein complex in infected cellsQ37099780
Transcription antitermination during influenza viral template RNA synthesis requires the nucleocapsid protein and the absence of a 5' capped end.Q37396534
The influenza A virus NS1 protein interacts with the nucleoprotein of viral ribonucleoprotein complexesQ39575224
A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesisQ40167332
Association of the influenza A virus RNA-dependent RNA polymerase with cellular RNA polymerase II.Q40435957
Interaction of the influenza a virus nucleocapsid protein with the viral RNA polymerase potentiates unprimed viral RNA replication.Q41965791
Separation of protein oligomers by blue native gel electrophoresisQ42005071
PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexesQ45707286
Influenza virus NS1 protein interacts with viral transcription-replication complexes in vivoQ45759828
The 3' and 5'-terminal sequences of influenza A, B and C virus RNA segments are highly conserved and show partial inverted complementarityQ45791400
Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factorQ24309374
Definition of the minimal viral components required for the initiation of unprimed RNA synthesis by influenza virus RNA polymeraseQ24548325
The mechanism by which influenza A virus nucleoprotein forms oligomers and binds RNAQ27640425
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active siteQ27653656
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunitQ27653657
Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replicationQ27863651
The active sites of the influenza cap-dependent endonuclease are on different polymerase subunitsQ27863698
Model suggesting that replication of influenza virus is regulated by stabilization of replicative intermediatesQ27863792
An unconventional NLS is critical for the nuclear import of the influenza A virus nucleoprotein and ribonucleoproteinQ27863807
RNA polymerase of influenza virus: role of NP in RNA chain elongationQ27865281
A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcriptionQ27865288
The influenza virus panhandle is involved in the initiation of transcriptionQ27865309
The NPI-1/NPI-3 (karyopherin alpha) binding site on the influenza a virus nucleoprotein NP is a nonconventional nuclear localization signalQ27867699
U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interactionQ28245108
Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3' end processing of cellular pre-mRNASQ28609773
Generation of influenza A viruses entirely from cloned cDNAsQ29616768
Airborne transmission of influenza A/H5N1 virus between ferretsQ29619970
The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.Q30353557
The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian hostQ30418377
Cellular splicing factor RAF-2p48/NPI-5/BAT1/UAP56 interacts with the influenza virus nucleoprotein and enhances viral RNA synthesisQ30978524
Genetic trans-complementation establishes a new model for influenza virus RNA transcription and replication.Q33455562
Influenza virus nucleoprotein interacts with influenza virus polymerase proteinsQ33784955
The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication.Q34119838
Glycine 184 in nonstructural protein NS1 determines the virulence of influenza A virus strain PR8 without affecting the host interferon responseQ34416678
Competition between influenza A virus genome segmentsQ34448295
The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathwayQ34598589
Replication-coupled and host factor-mediated encapsidation of the influenza virus genome by viral nucleoprotein.Q35077609
Contributions of two nuclear localization signals of influenza A virus nucleoprotein to viral replicationQ35634400
P304page(s)155
P577publication date2014-08-31
P1433published inVirology JournalQ7934868
P1476titleNuclear localized Influenza nucleoprotein N-terminal deletion mutant is deficient in functional vRNP formation
P478volume11

Reverse relations

cites work (P2860)
Q90598908A Quinolinone Compound Inhibiting the Oligomerization of Nucleoprotein of Influenza A Virus Prevents the Selection of Escape Mutants
Q40060300Genetic variation and co-evolutionary relationship of RNA polymerase complex segments in influenza A viruses
Q30398356Identification of influenza A nucleoprotein body domain residues essential for viral RNA expression expose antiviral target
Q64073204Nuclear localization of Newcastle disease virus matrix protein promotes virus replication by affecting viral RNA synthesis and transcription and inhibiting host cell transcription

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