Cyclooxygenase-2 induction by bradykinin in human pulmonary artery smooth muscle cells is mediated by the cyclic AMP response element through a novel autocrine loop involving endogenous prostaglandin E2, E-prostanoid 2 (EP2), and EP4 receptors.

scientific article

Cyclooxygenase-2 induction by bradykinin in human pulmonary artery smooth muscle cells is mediated by the cyclic AMP response element through a novel autocrine loop involving endogenous prostaglandin E2, E-prostanoid 2 (EP2), and EP4 receptors. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M307964200
P698PubMed publication ID14517215
P5875ResearchGate publication ID9074212

P50authorRobert NewtonQ39190184
Alan KnoxQ55030508
P2093author name stringLisa Corbett
Yong M Zhu
Dawn A Bradbury
Hala El-Haroun
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Muscarinic cholinergic receptor signal transduction as a potential target for the developmental neurotoxicity of ethanolQ33540749
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Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibitionQ33706082
Bradykinin and asthmaQ35601020
Bradykinin stimulates NF-kappaB activation and interleukin 1beta gene expression in cultured human fibroblastsQ37361105
Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cellsQ38349479
Transcriptional regulation of interleukin (IL)-8 by bradykinin in human airway smooth muscle cells involves prostanoid-dependent activation of AP-1 and nuclear factor (NF)-IL-6 and prostanoid-independent activation of NF-kappaB.Q40647721
Prostanoid receptors and their biological actionsQ40815197
Agonist stimulation of B1 and B2 kinin receptors causes activation of the MAP kinase signaling pathway, resulting in the translocation of AP-1 in HEK 293 cellsQ41005716
Bradykinin stimulates cAMP synthesis via mitogen-activated protein kinase-dependent regulation of cytosolic phospholipase A2 and prostaglandin E2 release in airway smooth muscleQ41874156
Bradykinin-dependent activation of adenylate cyclase activity and cyclic AMP accumulation in tracheal smooth muscle occurs via protein kinase C-dependent and -independent pathwaysQ41977942
Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1betaQ42548081
Design and synthesis of a highly selective EP2-receptor agonistQ43675039
Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism.Q43786752
Effect of bradykinin, TGF-beta1, IL-1beta, and hypoxia on COX-2 expression in pulmonary artery smooth muscle cells.Q44133734
Design and synthesis of a highly selective EP4-receptor agonist. Part 2: 5-thia and 9beta-haloPG derivatives with improved stabilityQ49224143
P433issue50
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
P1104number of pages11
P304page(s)49954-49964
P577publication date2003-09-29
P1433published inJournal of Biological ChemistryQ867727
P1476titleCyclooxygenase-2 induction by bradykinin in human pulmonary artery smooth muscle cells is mediated by the cyclic AMP response element through a novel autocrine loop involving endogenous prostaglandin E2, E-prostanoid 2 (EP2), and EP4 receptors
P478volume278

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