| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.YMGME.2003.08.009 |
| P953 | full work available at URL | https://api.elsevier.com/content/article/PII:S109671920300177X?httpAccept=text/plain |
| https://api.elsevier.com/content/article/PII:S109671920300177X?httpAccept=text/xml | ||
| P698 | PubMed publication ID | 14567954 |
| P5875 | ResearchGate publication ID | 231583345 |
| P2093 | author name string | Gregory M. Enns | |
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| Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators | Q28144781 | ||
| Glutamine:fructose-6-phosphate aminotransferase enzyme activity is necessary for the induction of TGF-beta1 and fibronectin expression in mesangial cells | Q28178641 | ||
| Diabetes mellitus associated with a pathogenic point mutation in mitochondrial DNA | Q28184211 | ||
| Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta | Q28188643 | ||
| A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA | Q28189066 | ||
| Friedreich ataxia: from GAA triplet-repeat expansion to frataxin deficiency | Q28200651 | ||
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| Reduction of lower motor neuron degeneration in wobbler mice by N-acetyl-L-cysteine | Q71786327 | ||
| Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly | Q72071043 | ||
| N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells | Q72170049 | ||
| Marked changes in mitochondrial DNA deletion levels in Alzheimer brains | Q72462720 | ||
| Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons | Q72643405 | ||
| Oxidative DNA damage in diabetes mellitus: its association with diabetic complications | Q73005624 | ||
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| Correction of pancreatic beta-cell dysfunction with coenzyme Q(10) in a patient with mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes syndrome and diabetes mellitus | Q73281188 | ||
| Glucose-induced changes in protein kinase C and nitric oxide are prevented by vitamin E | Q73376994 | ||
| Glutamate is not a messenger in insulin secretion | Q74248128 | ||
| Genetics of diabetes mellitus | Q74457461 | ||
| Prevention of PC12 cell death by N-acetylcysteine requires activation of the Ras pathway | Q74562743 | ||
| The pharmacokinetics and pharmaco-dynamics of Procysteine in amyotrophic lateral sclerosis | Q77398292 | ||
| Sequential inactivation of reactive oxygen species by combined overexpression of SOD isoforms and catalase in insulin-producing cells | Q44359857 | ||
| Insulin and glucagon regulation of glutathione S-transferase expression in primary cultured rat hepatocytes | Q44370462 | ||
| Mitochondrial defect in Huntington's disease caudate nucleus | Q45291734 | ||
| Biochemical abnormalities and excitotoxicity in Huntington's disease brain. | Q45297145 | ||
| Mutations in SDHC cause autosomal dominant paraganglioma, type 3. | Q47817141 | ||
| Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases. | Q47830583 | ||
| Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease | Q48127846 | ||
| Abnormalities of mitochondrial enzymes in Alzheimer disease | Q48320241 | ||
| Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age | Q48403808 | ||
| Autism: a mitochondrial disorder? | Q48408503 | ||
| Oxidative damage in Alzheimer's | Q48964533 | ||
| The effects of coenzyme Q10 treatment on maternally inherited diabetes mellitus and deafness, and mitochondrial DNA 3243 (A to G) mutation. | Q50505250 | ||
| A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA. | Q50525235 | ||
| Decreased mitochondrial DNA content in peripheral blood precedes the development of non-insulin-dependent diabetes mellitus. | Q50536954 | ||
| Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness | Q50537181 | ||
| New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus. | Q50919931 | ||
| Ca(2+)- and GTP-dependent exocytosis in mouse pancreatic beta-cells involves both common and distinct steps. | Q52295297 | ||
| Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis. | Q52530987 | ||
| Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes. | Q52541455 | ||
| Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients. | Q53206553 | ||
| Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients. | Q53321449 | ||
| Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis. | Q53920238 | ||
| Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin. | Q54062879 | ||
| An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria | Q54965159 | ||
| Glucose Down-regulates the Expression of the Peroxisome Proliferator-activated Receptor-α Gene in the Pancreatic β-Cell | Q57494265 | ||
| Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease | Q58006825 | ||
| Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion | Q67482157 | ||
| Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma | Q28366764 | ||
| Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator | Q28505376 | ||
| Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease | Q29398392 | ||
| Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma | Q29614552 | ||
| Gene expression profile of aging and its retardation by caloric restriction | Q29614554 | ||
| Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage | Q29616101 | ||
| The free radical theory of aging matures | Q29618019 | ||
| Interaction among mitochondria, mitogen-activated protein kinases, and nuclear factor-kappaB in cellular models of Parkinson's disease | Q30305512 | ||
| The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism. | Q30473178 | ||
| Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death | Q33538979 | ||
| Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia | Q33540916 | ||
| Mitochondrial involvement in Alzheimer's disease | Q33540918 | ||
| Transfer of beta-amyloid precursor protein gene using adenovirus vector causes mitochondrial abnormalities in cultured normal human muscle | Q33557364 | ||
| Molecular scanning of candidate mitochondrial tRNA genes in type 2 (non-insulin dependent) diabetes mellitus. | Q33683405 | ||
| Evidence that the mitochondrial genome is the thrifty genome | Q33788665 | ||
| Use of cytoplasmic hybrid cell lines for elucidating the role of mitochondrial dysfunction in Alzheimer's disease and Parkinson's disease | Q33836235 | ||
| Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication | Q33877846 | ||
| beta-cell genes and diabetes: molecular and clinical characterization of mutations in transcription factors | Q33939828 | ||
| Glutathione, oxidative stress and neurodegeneration | Q33994473 | ||
| Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell | Q34083615 | ||
| Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer | Q34115940 | ||
| Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response | Q34120367 | ||
| High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison | Q34193191 | ||
| Thiamine-responsive megaloblastic anemia syndrome: a disorder of high-affinity thiamine transport. | Q34254404 | ||
| Molecular and clinical aspects of mitochondrial diabetes mellitus | Q34284522 | ||
| Inclusion body myositis and myopathies | Q34289237 | ||
| Mitochondrial defects in neurodegenerative disease | Q34366678 | ||
| Mouse models for mitochondrial disease | Q34386758 | ||
| Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells | Q34433078 | ||
| Mitochondrial function in normal and diabetic beta-cells | Q34462332 | ||
| Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia? | Q34464761 | ||
| Molecular targets of a human HNF1 alpha mutation responsible for pancreatic beta-cell dysfunction | Q34486684 | ||
| Germ-line mutations in nonsyndromic pheochromocytoma | Q34523021 | ||
| Impairment of brain mitochondrial function by reactive nitrogen species: the role of glutathione in dictating susceptibility | Q34535088 | ||
| Mitochondrial contributions to tissue damage in stroke | Q34535121 | ||
| Mitochondrial involvement in Parkinson's disease | Q34535137 | ||
| Spinocerebellar ataxias due to mitochondrial defects | Q34535150 | ||
| Mitochondrial diabetes: pathophysiology, clinical presentation, and genetic analysis | Q34737294 | ||
| The role of mitochondria and oxidative stress in neuronal damage after brief and prolonged seizures | Q34763796 | ||
| Oxidative stress and nitration in neurodegeneration: cause, effect, or association? | Q35047296 | ||
| Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection | Q35073626 | ||
| Diabetes, oxidative stress, and antioxidants: a review | Q35077717 | ||
| A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease | Q35166007 | ||
| Advanced glycation end products contribute to amyloidosis in Alzheimer disease | Q35285651 | ||
| Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease | Q35340937 | ||
| Increased expression of mitochondrial-encoded genes in skeletal muscle of humans with diabetes mellitus | Q35554282 | ||
| N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro | Q35642650 | ||
| Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia | Q35653693 | ||
| Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress | Q35664175 | ||
| Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2 | Q35752125 | ||
| Detection of a specific mitochondrial DNA deletion in tissues of older humans | Q35891834 | ||
| Protective actions of YM737, a new glutathione analog, against cerebral ischemia in rats | Q36752913 | ||
| Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow | Q36762569 | ||
| Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus | Q37350875 | ||
| Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? | Q37936915 | ||
| Frataxin expression rescues mitochondrial dysfunctions in FRDA cells | Q38296053 | ||
| Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. | Q38299277 | ||
| Diabetes mellitus associated with 3243 mitochondrial tRNA(Leu(UUR)) mutation: clinical features and coenzyme Q10 treatment | Q39459050 | ||
| High glucose-induced transforming growth factor beta1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells | Q39796701 | ||
| Glucokinase as pancreatic beta cell glucose sensor and diabetes gene | Q40305563 | ||
| Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. | Q40721588 | ||
| Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts | Q41009444 | ||
| Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6. | Q41157792 | ||
| Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease | Q41206150 | ||
| Reactive oxygen-mediated protein oxidation in aging and disease | Q41485816 | ||
| Point mutations of the mtDNA control region in normal and neurodegenerative human brains | Q41809123 | ||
| Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action | Q42504879 | ||
| Peripheral blood mitochondrial DNA content is inversely correlated with insulin secretion during hyperglycemic clamp studies in healthy young men. | Q43581451 | ||
| Maternally inherited diabetes and deafness: a multicenter study | Q43592578 | ||
| Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases | Q43599271 | ||
| Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy | Q43687875 | ||
| Glutathione in blood of patients with Friedreich's ataxia. | Q43818051 | ||
| Mitochondrial dysfunction in patients with hypotonia, epilepsy, autism, and developmental delay: HEADD syndrome | Q44099492 | ||
| Assessment of DNA base oxidation and glutathione level in patients with type 2 diabetes. | Q44100506 | ||
| Effects of alpha lipoic acid, ascorbic acid-6-palmitate, and fish oil on the glutathione, malonaldehyde, and fatty acids levels in erythrocytes of streptozotocin induced diabetic male rats | Q44124925 | ||
| Effect of oxidative stress on glutathione pathway in red blood cells from patients with insulin-dependent diabetes mellitus | Q44172562 | ||
| Impaired ascorbic acid metabolism in streptozotocin-induced diabetic rats | Q44193398 | ||
| P433 | issue | 1-2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endocrinology | Q162606 |
| biochemistry | Q7094 | ||
| genetics | Q7162 | ||
| mitochondrion | Q39572 | ||
| P304 | page(s) | 11-26 | |
| P577 | publication date | 2003-09-01 | |
| P1433 | published in | Molecular Genetics and Metabolism | Q6895949 |
| P1476 | title | The contribution of mitochondria to common disorders | |
| P478 | volume | 80 |
| Q42089040 | A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability |
| Q35896422 | Age-associated reduction of cell spreading induces mitochondrial DNA common deletion by oxidative stress in human skin dermal fibroblasts: implication for human skin connective tissue aging |
| Q60687693 | Alterations in Inflammatory Mediators, Oxidative Stress Parameters and Energetic Metabolism in the Brain of Sepsis Survivor Rats |
| Q28384299 | Bench-to-bedside review: Mitochondrial injury, oxidative stress and apoptosis--there is nothing more practical than a good theory |
| Q46467425 | Brain Oxidative Stress During Experimental Sepsis Is Attenuated by Simvastatin Administration. |
| Q24647385 | Chronic fatigue syndrome and mitochondrial dysfunction |
| Q33665573 | DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions |
| Q54613942 | Development of a human mitochondria-focused cDNA microarray (hMitChip) and validation in skeletal muscle cells: implications for pharmaco- and mitogenomics. |
| Q24633323 | Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity and disease |
| Q22241227 | Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism |
| Q48534978 | Extended exposure to sugar and/or caffeine produces distinct behavioral and neurochemical profiles in the orbitofrontal cortex of rats: Implications for neural function. |
| Q37239235 | Flex-Hets differentially induce apoptosis in cancer over normal cells by directly targeting mitochondria |
| Q40421940 | In vitro correction of medium chain acyl CoA dehydrogenase deficiency with a recombinant adenoviral vector. |
| Q34342139 | Increases in mitochondrial DNA content and 4977-bp deletion upon ATM/Chk2 checkpoint activation in HeLa cells |
| Q37129457 | Inherited disorders affecting mitochondrial function are associated with glutathione deficiency and hypocitrullinemia |
| Q21145361 | Mapping gene associations in human mitochondria using clinical disease phenotypes |
| Q35218544 | Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection |
| Q47808754 | Melatonin, mitochondria, and the cancer cell. |
| Q36359505 | Mitochondria as a target for early detection and diagnosis of cancer |
| Q38253091 | Mitochondria as a target in the therapeutic properties of curcumin. |
| Q90190632 | Mitochondrial Epigenetics: Non-Coding RNAs as a Novel Layer of Complexity |
| Q35027083 | Mitochondrial Variations in Non-Small Cell Lung Cancer (NSCLC) Survival |
| Q24630557 | Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis |
| Q37764793 | Mitochondrial dysfunction in neurodegenerative diseases and cancer |
| Q37618225 | Mitochondrial gene profiling: translational perspectives |
| Q37076893 | Mitochondrial pathophysiology, reactive oxygen species, and cardiovascular diseases |
| Q42122769 | Modeling the mitochondrial dysfunction in neurogenerative diseases due to high H+ concentration |
| Q43171710 | Modulating effect of Withania somnifera on TCA cycle enzymes and electron transport chain in azoxymethane-induced colon cancer in mice |
| Q84170487 | Pharmacological effect of carvacrol on D: -galactosamine-induced mitochondrial enzymes and DNA damage by single-cell gel electrophoresis |
| Q54278545 | Protein "amyloid-like" networks at the phospholipid membrane formed by 4-hydroxy-2-nonenal-modified mitochondrial creatine kinase. |
| Q42716626 | Rat mitochondrion-neuron focused microarray (rMNChip) and bioinformatics tools for rapid identification of differential pathways in brain tissues |
| Q36561388 | Role of cardiolipin alterations in mitochondrial dysfunction and disease |
| Q36972082 | Synthesis and investigation of the 5-formylcytidine modified, anticodon stem and loop of the human mitochondrial tRNAMet |
| Q26786969 | The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis |
| Q34675040 | The human T-cell leukemia virus type 1 p13II protein: effects on mitochondrial function and cell growth |
| Q38198015 | The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders |
| Q38566683 | Therapeutic applications of the TAT-mediated protein transduction system for complex I deficiency and other mitochondrial diseases |
| Q37923355 | Transduction of human recombinant proteins into mitochondria as a protein therapeutic approach for mitochondrial disorders |
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