Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study.

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Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1200/JCO.2011.38.4032
P698PubMed publication ID22547592

P50authorIgor N. BondarenkoQ30957829
Piotr SerwatowskiQ114456257
P2093author name stringMartin Reck
Thomas J Lynch
Fabrice Barlesi
Haolan Lu
Martin Sebastian
Jean-Marie Cuillerot
Joel Neal
Raju Chacko
Alexander Luft
P2860cites workCTLA-4 can function as a negative regulator of T cell activationQ28235866
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectmulticenter clinical trialQ6934595
lung cancerQ47912
paclitaxelQ423762
ipilimumabQ2459042
carboplatinQ415588
P304page(s)2046-2054
P577publication date2012-04-30
P1433published inJournal of Clinical OncologyQ400292
P1476titleIpilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study
P478volume30

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Q38527663Precision Therapy for Lung Cancer: Tyrosine Kinase Inhibitors and Beyond.
Q36350628Prediction of cancer cell sensitivity to natural products based on genomic and chemical properties.
Q91828758Prevalence of DLL3, CTLA-4 and MSTN Expression in Patients with Small Cell Lung Cancer
Q26745590Profile of nivolumab in the treatment of metastatic squamous non-small-cell lung cancer
Q36769318Prognostic impact of tumour-associated B cells and plasma cells in epithelial ovarian cancer
Q40802902Prognostic impact of tumour-infiltrating B cells and plasma cells in colorectal cancer
Q124854868Prognostic influence of PD-1/PD-L1 suppressors in combination with chemotherapeutic agents for non-small cell pulmonary carcinoma: system review and meta-analysis
Q36916445Prognostic value of tumor-infiltrating lymphocytes for patients with completely resected stage IIIA(N2) non-small cell lung cancer
Q26865725Progress in immunotherapy for non-small cell lung cancer
Q28083663Promising targets and current clinical trials in metastatic squamous cell lung cancer
Q46166592Promoter hypomethylation of NY-ESO-1, association with clinicopathological features and PD-L1 expression in non-small cell lung cancer
Q36821194Prospective strategies to combine conventional, targeted and immunotherapies in non-small cell lung cancer.
Q39198154Prospects for combining targeted and conventional cancer therapy with immunotherapy
Q55000624Putting the brakes on CTLA-4 inhibition in lung cancer?
Q39017268Radiotherapy and immunotherapy: a beneficial liaison?
Q26738443Radiotherapy combination opportunities leveraging immunity for the next oncology practice
Q57823167Radiotherapy induces responses of lung cancer to CTLA-4 blockade
Q38514601Rationale for targeting the ErbB family of receptors in patients with advanced squamous cell carcinoma of the lung.
Q38080047Rationale for targeting the immune system through checkpoint molecule blockade in the treatment of non-small-cell lung cancer.
Q38099562Re-examination of maintenance therapy in non-small cell lung cancer with the advent of new anti-cancer agents
Q28069323Recent Advances in Immunotherapy in Metastatic NSCLC
Q34290801Recent advances in immunotherapy for non-small-cell lung cancer
Q38826419Recent developments in the use of immunotherapy in non-small cell lung cancer
Q38168904Recent progress in peptide vaccination in cancer with a focus on non-small-cell lung cancer
Q38473314Regulatory T cells and potential inmmunotherapeutic targets in lung cancer
Q34537285Response assessment in metastatic melanoma treated with ipilimumab and bevacizumab: CT tumor size and density as markers for response and outcome
Q64271422Risk and incidence of fatal adverse events associated with immune checkpoint inhibitors: a systematic review and meta-analysis
Q90642504Risk of Gastrointestinal Adverse Events in Cancer Patients Treated With Immune Checkpoint Inhibitor Plus Chemotherapy: A Systematic Review and Meta-Analysis
Q38566770Risk of cutaneous toxicities in patients with solid tumors treated with immune checkpoint inhibitors: a meta-analysis.
Q38591135Risk of elevated transaminases in cancer patients treated with immune checkpoint inhibitors: a meta-analysis.
Q38699309Risk of endocrine complications in cancer patients treated with immune check point inhibitors: a meta-analysis.
Q31171172Risk of hepatotoxicity in cancer patients treated with immune checkpoint inhibitors: A systematic review and meta-analysis of published data
Q50020799Robust Antitumor Responses Result from Local Chemotherapy and CTLA-4 Blockade.
Q57174372Role of Immunotherapy for Oncogene-Driven Non-Small Cell Lung Cancer
Q93172097Role of cytokines in combinatorial immunotherapeutics of non-small cell lung cancer through systems perspective
Q49549096Role of immune-checkpoint inhibitors in lung cancer
Q38443020Role of immunotherapy in lung cancer: Preliminary results of new vaccines and immune checkpoint inhibitors.
Q38170384Role of immunotherapy in the treatment of advanced non-small-cell lung cancer.
Q92073794Safety and Efficacy Results of a Phase I, Open-Label Study of Concurrent and Delayed Nivolumab in Combination With nab-Paclitaxel and Carboplatin in Advanced Non-small Cell Lung Cancer
Q30251438Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination
Q26775876Second-line combination therapies in nonsmall cell lung cancer without known driver mutations
Q36298852Sequencing of BRAF inhibitors and ipilimumab in patients with metastatic melanoma: a possible algorithm for clinical use.
Q38661099Single versus combination immunotherapy drug treatment in melanoma
Q35836257Small cell lung cancer: will recent progress lead to improved outcomes?
Q37175437Spine Stereotactic Body Radiotherapy Outcomes in Patients with Concurrent Brain Metastases
Q38749639Standard of care in immunotherapy trials: Challenges and considerations.
Q34681069State of the art: Response assessment in lung cancer in the era of genomic medicine
Q91742496Stereotactic Ablative Radiotherapy Combined with Immune Checkpoint Inhibitors Reboots the Immune Response Assisted by Immunotherapy in Metastatic Lung Cancer: A Systematic Review
Q47278600Surrogate end points for overall survival in trials of PD-(L)1 inhibitors for urinary cancers: a systematic review
Q28486600Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity
Q37126642Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models
Q38529051Systematic review: colitis associated with anti-CTLA-4 therapy.
Q26865490Systemic and targeted therapies for early-stage lung cancer
Q92830528Targeted Therapies in Non-small-Cell Lung Cancer
Q33585089Targeted immunotherapy for non-small cell lung cancer
Q38625550Targeted therapies for treatment of non-small cell lung cancer--Recent advances and future perspectives
Q27022852Targeted therapies in development for non-small cell lung cancer
Q36999705Targeted therapies in non-small cell lung carcinoma: what have we achieved so far?
Q37709922Targeted therapy for non-small-cell lung cancer: past, present and future
Q37246286Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer
Q38956294Targeting PD-1/PD-L1 in lung cancer: current perspectives
Q38720801Targeting the PD-1/PD-L1 Immune Checkpoint in EGFR-Mutated or ALK-Translocated Non-Small-Cell Lung Cancer.
Q38128228Targeting the immune system in the treatment of non-small-cell lung cancer
Q38397629Targeting the immune system to treat lung cancer: rationale and clinical experience.
Q52740477The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.
Q26796549The Efficacy of Combining EGFR Monoclonal Antibody With Chemotherapy for Patients With Advanced Nonsmall Cell Lung Cancer: A Meta-Analysis From 9 Randomized Controlled Trials
Q38401891The Era of Checkpoint Blockade in Lung Cancer: Taking the Brakes Off the Immune System
Q26738677The European Organization for Research and Treatment of Cancer perspective on designing clinical trials with immune therapeutics
Q26786932The Evolution of Therapies in Non-Small Cell Lung Cancer
Q27022789The Evolving Role of Immune Checkpoint Inhibitors in Cancer Treatment
Q52582484The Great Debate at "Melanoma Bridge", Napoli, December 2nd, 2017.
Q38679301The Microenvironment of Lung Cancer and Therapeutic Implications
Q53107269The Prognostic Significance of pSTAT1 and CD163 Expressions in Surgically Resected Stage 1 Pulmonary Squamous Cell Carcinomas.
Q28066568The Utilization of the Immune System in Lung Cancer Treatment: Beyond Chemotherapy
Q36169794The antigenic landscape of multiple myeloma: mass spectrometry (re)defines targets for T-cell-based immunotherapy
Q47916852The clinical value of combination of immune checkpoint inhibitors in cancer patients: A meta-analysis of efficacy and safety
Q90352646The different benefits and side effects of nivolumab combined with ipilimumab in diverse cancer: A Protocol for Systematic Review
Q58698737The efficacy and safety of immune checkpoint inhibitor combination therapy in lung cancer: a systematic review and meta-analysis
Q33434828The efficacy and safety of immunotherapy in patients with advanced NSCLC: a systematic review and meta-analysis.
Q28081893The interplay of immunotherapy and chemotherapy: harnessing potential synergies
Q26823305The latest therapeutic strategies after resistance to first generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) in patients with non-small cell lung cancer (NSCLC)
Q38824489The next generation of immunotherapy: keeping lung cancer in check.
Q26799896The past, present and future of immunotherapy against tumor
Q46200598The race for combined checkpoint inhibition in NSCLC.
Q34917875The role of Cancer-Testis antigens as predictive and prognostic markers in non-small cell lung cancer.
Q34402325The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014
Q38875474The role of myeloid cells in cancer therapies
Q47138418The sexist behaviour of immune checkpoint inhibitors in cancer therapy?
Q42336242Theory Meets Practice for Immune Checkpoint Blockade in Small-Cell Lung Cancer
Q90407151Three discipline collaborative radiation therapy (3DCRT) special debate: The single most important factor in determining the future of SBRT is immune response
Q57298272Tobacco smoking and cessation and PD-L1 inhibitors in non-small cell lung cancer (NSCLC): a review of the literature
Q38739807Treatment modalities for advanced ALK-rearranged non-small-cell lung cancer
Q26775392Treatment of advanced squamous cell carcinoma of the lung: a review
Q44807139Tremelimumab for patients with chemotherapy-resistant advanced malignant mesothelioma: an open-label, single-arm, phase 2 trial
Q38631254Tremelimumab for the treatment of malignant mesothelioma
Q28067674Trends and advances in tumor immunology and lung cancer immunotherapy
Q42847992Trial Watch: Anticancer radioimmunotherapy
Q43104064Trial Watch: Radioimmunotherapy for oncological indications
Q56932681Trial watch: Monoclonal antibodies in cancer therapy
Q37022378Tumor CTLA-4 overexpression predicts poor survival in patients with nasopharyngeal carcinoma
Q49434203Tumor Immunology and Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer
Q58096039Tumour cell-intrinsic CTLA4 regulates PD-L1 expression in non-small cell lung cancer
Q39239026Tuning cancer fate: the unremitting role of host immunity.
Q38205723Unmet needs in squamous cell carcinoma of the lung: potential role for immunotherapy
Q24619675Update in lung cancer and mesothelioma 2012
Q56897146Update on immune checkpoint inhibitors in lung cancer
Q37462524Upregulation of programmed cell death ligand 1 promotes resistance response in non-small-cell lung cancer patients treated with neo-adjuvant chemotherapy
Q39181190VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy
Q36868927Venovenous perfusion-induced systemic hyperthermia: five-day sheep survival studies
Q39791206Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses.
Q38856436What does the future hold for immunotherapy in cancer?
Q40065733What have we learned from cancer immunotherapy in the last 3 years?
Q38193716What is the role of chemotherapy in the treatment of melanoma?
Q37301472What lies within: novel strategies in immunotherapy for non-small cell lung cancer
Q36207901Why has active immunotherapy not worked in lung cancer?
Q55441788[Advances in immunotherapies for non-small cell lung cancer].
Q54380709[Progress in Immunotherapy for Squamous Non-small Cell Lung Cancer].
Q55436672[Review on immunotherapies for lung cancer].
Q52879625[The pathology of adverse events with immune checkpoint inhibitors].
Q38748974iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics
Q37536367nab-Paclitaxel as a potential partner with checkpoint inhibitors in solid tumors

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