Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma

scientific article

Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JPEDSURG.2013.09.051
P932PMC publication ID4183462
P698PubMed publication ID24439602

P2093author name stringDai H Chung
Kwang Woon Kim
Jingbo Qiao
Sora Lee
Pritha Paul
Carmelle Romain
P2860cites workStabilization of N-Myc is a critical function of Aurora A in human neuroblastomaQ24311457
Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridizationQ24564349
The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cellsQ27851718
Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformationQ28285317
Pediatric phase I trial and pharmacokinetic study of MLN8237, an investigational oral selective small-molecule inhibitor of Aurora kinase A: a Children's Oncology Group Phase I Consortium studyQ33559116
Aurora kinase inhibitors--rising stars in cancer therapeutics?Q33647643
Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP).Q33867046
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myelomaQ33944281
Myc proteins as therapeutic targetsQ33997741
Characteristics of stem cells from human neuroblastoma cell lines and in tumorsQ34928930
Pediatric neuroblastomas: genetic and epigenetic 'danse macabre'.Q35617266
Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonistsQ36642293
Additive effects of vorinostat and MLN8237 in pediatric leukemia, medulloblastoma, and neuroblastoma cell linesQ36849233
FAK is a critical regulator of neuroblastoma liver metastasisQ36926116
N-myc is a novel regulator of PI3K-mediated VEGF expression in neuroblastomaQ37038002
The aurora kinase A regulates GSK-3beta in gastric cancer cellsQ37096754
Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism.Q37594844
Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastomaQ37663791
Biology of Aurora A kinase: implications in cancer manifestation and therapyQ37701369
PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancerQ37929638
Regulation of gene transcription by the oncoprotein MYC.Q37974026
Effects of stable knockdown of Aurora kinase A on proliferation, migration, chromosomal instability, and expression of focal adhesion kinase and matrix metalloproteinase-2 in HEp-2 cellsQ39540720
Expression of vascular endothelial growth factor (VEGF) and VEGF receptors in human neuroblastomasQ40875496
NeuroblastomaQ54265665
Comparative genomic in situ hybridization of colon carcinomas with replication errorQ70786829
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
P304page(s)159-165
P577publication date2013-10-05
P1433published inJournal of Pediatric SurgeryQ15761821
P1476titleTargeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma
P478volume49

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cites work (P2860)
Q35790720ABCG2 impairs the activity of the aurora kinase inhibitor tozasertib but not of alisertib
Q37442586Antitumor activity of TY-011 against gastric cancer by inhibiting Aurora A, Aurora B and VEGFR2 kinases
Q28543446Aurora kinases as targets in drug-resistant neuroblastoma cells
Q33618929Aurora kinases: novel therapy targets in cancers
Q38894287Aurora-A Kinase: A Potent Oncogene and Target for Cancer Therapy
Q92305240CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation
Q26771708Cell Proliferation in Neuroblastoma
Q38868413Clear cell renal cell carcinoma: identifying the gain of chromosome 20 on multiphasic MDCT.
Q37338152Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay
Q88426580Lack of associations between AURKA gene polymorphisms and neuroblastoma susceptibility in Chinese children
Q92402049MRI Imaging of the Hemodynamic Vasculature of Neuroblastoma Predicts Response to Antiangiogenic Treatment
Q89622450Molecular Links Between Angiogenesis and Neuroendocrine Phenotypes in Prostate Cancer Progression
Q35493637Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer
Q34194552Targeting aurora kinase A inhibits hypoxia-mediated neuroblastoma cell tumorigenesis
Q39208675The MYCN Protein in Health and Disease

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