| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2014PLoSO...9j9213C |
| P356 | DOI | 10.1371/JOURNAL.PONE.0109213 |
| P932 | PMC publication ID | 4183563 |
| P698 | PubMed publication ID | 25275497 |
| P5875 | ResearchGate publication ID | 266572164 |
| P50 | author | Jerry Pelletier | Q85559340 |
| P2093 | author name string | Francis Robert | |
| T Martin Schmeing | |||
| Regina Cencic | |||
| Hisashi Miura | |||
| Josée Dostie | |||
| Abba Malina | |||
| Sylvain Ethier | |||
| P2860 | cites work | Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects | Q52422958 |
| Cas9 as a versatile tool for engineering biology | Q24564294 | ||
| RNA-guided human genome engineering via Cas9 | Q24598394 | ||
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| RNA-programmed genome editing in human cells | Q28044562 | ||
| Probing tumor phenotypes using stable and regulated synthetic microRNA precursors | Q28275174 | ||
| Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients | Q28303521 | ||
| One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering | Q29547524 | ||
| CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering | Q29615783 | ||
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| DNA interrogation by the CRISPR RNA-guided endonuclease Cas9. | Q33931841 | ||
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| Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy | Q34478557 | ||
| Correction of a genetic disease in mouse via use of CRISPR-Cas9. | Q34658184 | ||
| MEME-ChIP: motif analysis of large DNA datasets | Q35019674 | ||
| Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation | Q35861554 | ||
| High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity | Q37196274 | ||
| CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity | Q37271186 | ||
| Repurposing CRISPR/Cas9 for in situ functional assays. | Q37388903 | ||
| Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. | Q37420333 | ||
| Hox in motion: tracking HoxA cluster conformation during differentiation | Q37574219 | ||
| Transgene-free genome editing in Caenorhabditis elegans using CRISPR-Cas | Q41955405 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | CRISPR | Q412563 |
| Cas9 | Q16965677 | ||
| CRISPR-Cas method | Q17310682 | ||
| P304 | page(s) | e109213 | |
| P577 | publication date | 2014-10-02 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage | |
| P478 | volume | 9 |
| Q92069945 | A CRISPR View of Biological Mechanisms |
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| Q26781135 | A new age in functional genomics using CRISPR/Cas9 in arrayed library screening |
| Q42397056 | Allele-specific locus binding and genome editing by CRISPR at the p16INK4a locus |
| Q26745534 | An Overview of CRISPR-Based Tools and Their Improvements: New Opportunities in Understanding Plant-Pathogen Interactions for Better Crop Protection |
| Q28083457 | Applications of Cas9 as an RNA-programmed RNA-binding protein |
| Q26781399 | Applications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology Research |
| Q28069780 | Biased and Unbiased Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9: An Overview |
| Q26773177 | Biochemical Analysis of Genome Functions Using Locus-Specific Chromatin Immunoprecipitation Technologies |
| Q89984111 | Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches |
| Q37656508 | CRISPR as a strong gene editing tool |
| Q48102787 | CRISPR interference-based specific and efficient gene inactivation in the brain. |
| Q39014648 | CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes |
| Q39219057 | CRISPR-Cas9 Structures and Mechanisms |
| Q89873570 | CRISPR/Cas9-mediated genome editing: From basic research to translational medicine |
| Q38614582 | CRISPR/Cas9: molecular tool for gene therapy to target genome and epigenome in the treatment of lung cancer |
| Q36879255 | Conformational control of DNA target cleavage by CRISPR-Cas9. |
| Q90024609 | Correction of IVS I-110(G>A) β-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells |
| Q24669821 | Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system |
| Q38810667 | Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases |
| Q52360880 | Designing Epigenome Editors: Considerations of Biochemical and Locus Specificities |
| Q97646316 | Development of a Self-Restricting CRISPR-Cas9 System to Reduce Off-Target Effects |
| Q46347859 | Enhanced proofreading governs CRISPR-Cas9 targeting accuracy |
| Q34454104 | GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases |
| Q26752488 | Genome Engineering with TALE and CRISPR Systems in Neuroscience |
| Q26777801 | How specific is CRISPR/Cas9 really? |
| Q38704784 | Identification of physical interactions between genomic regions by enChIP-Seq. |
| Q40842003 | In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide RNA and a DNA Target |
| Q38804017 | In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining |
| Q41438593 | Increasing on-target cleavage efficiency for CRISPR/Cas9-induced large fragment deletion in Myxococcus xanthus |
| Q52430693 | Inducible Genome Editing with Conditional CRISPR/Cas9 Mice |
| Q38828241 | Isolation of Specific Genomic Regions and Identification of Associated Molecules by enChIP. |
| Q26786952 | Isolation of Specific Genomic Regions and Identification of Their Associated Molecules by Engineered DNA-Binding Molecule-Mediated Chromatin Immunoprecipitation (enChIP) Using the CRISPR System and TAL Proteins |
| Q38701144 | Locus-specific ChIP combined with NGS analysis reveals genomic regulatory regions that physically interact with the Pax5 promoter in a chicken B cell line |
| Q38598073 | Modeling Disease In Vivo With CRISPR/Cas9. |
| Q26859390 | Off-target Effects in CRISPR/Cas9-mediated Genome Engineering |
| Q36392460 | PAM multiplicity marks genomic target sites as inhibitory to CRISPR-Cas9 editing |
| Q38840857 | Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing |
| Q64989716 | Precision gene editing technology and applications in nephrology. |
| Q38700979 | Progress and Application of CRISPR/Cas Technology in Biological and Biomedical Investigation |
| Q37639765 | Progress in Genome Editing Technology and Its Application in Plants |
| Q47099565 | Randomized CRISPR-Cas Transcriptional Perturbation Screening Reveals Protective Genes against Alpha-Synuclein Toxicity. |
| Q37263726 | Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9. |
| Q36160691 | Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage |
| Q37577414 | TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus |
| Q45975621 | Targeted genome editing in Caenorhabditis elegans using CRISPR/Cas9. |
| Q38896928 | The genome editing revolution: A CRISPR-Cas TALE off-target story. |
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