| P50 | author | Larry Claxton | Q43091668 |
| | Gisela A Umbuzeiro | Q50078571 |
| P2093 | author name string | David M. DeMarini | |
| P2860 | cites work | Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection | Q24564216 |
| | An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens | Q24564335 |
| | Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens | Q24615830 |
| | Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion | Q24617004 |
| | Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals | Q24618873 |
| | An integrated genomic analysis of human glioblastoma multiforme | Q24648860 |
| | The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development | Q39763925 |
| | Environmental mutagens and carcinogens | Q39790031 |
| | Chemical characterization of 465 known or suspected carcinogens and their correlation with mutagenic activity in the Salmonella typhimurium system | Q39805996 |
| | Immunological aspects of chemical carcinogenesis | Q39870070 |
| | Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme | Q39970246 |
| | Current and future application of genetic toxicity assays: the role and value of in vitro mammalian assays | Q39990800 |
| | Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture | Q39991517 |
| | Mutagenicity and genotoxicity of nitroarenes. All nitro-containing chemicals were not created equal | Q40134033 |
| | Stratification of rodent carcinogenicity bioassay results to reflect relative human hazard | Q40484628 |
| | Biomarker assays in nipple aspirate fluid | Q40660427 |
| | Airborne Mutagens Bioassayed in Salmonella typhimurium2 | Q40746268 |
| | The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assays | Q41155504 |
| | Development and validation of the spiral Salmonella assay: an automated approach to bacterial mutagenicity testing | Q41235248 |
| | Mutagen screening by a simplified bacterial fluctuation test: Use of microsomal preparations and whole liver cells for metabolic activation | Q41274738 |
| | Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity St | Q41376780 |
| | The dose-response relationship for ultraviolet-light-induced mutations at the hypoxanthine-guanine phosphoribosyltransferase locus in Chinese hamster ovary cells | Q42803865 |
| | Residue organic mixtures from drinking water showin vitromutagenic and transforming activity | Q42830425 |
| | TSCA reform under way in Congress. | Q42838986 |
| | Identification of organic compounds and ecotoxicological assessment of sewage treatment plants (STP) effluents | Q43311888 |
| | Genotoxicity of industrial wastes and effluents | Q43333337 |
| | The genomic landscapes of human breast and colorectal cancers | Q27861078 |
| | Chemical regulators have overreached | Q27921860 |
| | Occurrence, genotoxicity, and carcinogenicity of regulated and emerging disinfection by-products in drinking water: a review and roadmap for research | Q28255949 |
| | The epigenomics of cancer | Q28289975 |
| | Chromosome tests with 134 compounds on Chinese hamster cells in vitro--a screening for chemical carcinogens | Q28332141 |
| | Toward a new U.S. chemicals policy: rebuilding the foundation to advance new science, green chemistry, and environmental health | Q30397312 |
| | Use of cell viability assay data improves the prediction accuracy of conventional quantitative structure-activity relationship models of animal carcinogenicity | Q31152707 |
| | Require comprehensive safety data for all chemicals | Q33303823 |
| | A toxicology for the 21st century--mapping the road ahead | Q33346986 |
| | Benchmark data set for in silico prediction of Ames mutagenicity | Q33496207 |
| | Understanding genetic toxicity through data mining: the process of building knowledge by integrating multiple genetic toxicity databases | Q33519661 |
| | Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. | Q33530396 |
| | Mutation spectra resulting from carcinogenic exposure: from model systems to cancer-related genes | Q33534961 |
| | Influence of DNA repair on mutation spectra in Salmonella | Q33933742 |
| | Evaluation of fecal mutagenicity and colorectal cancer risk | Q33933800 |
| | The mutagenic hazards of aquatic sediments: a review. | Q33983423 |
| | Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects | Q33988929 |
| | Sensitive method for the detection of mutagenic nitroarenes and aromatic amines: new derivatives of Salmonella typhimurium tester strains possessing elevated O-acetyltransferase levels | Q34095756 |
| | Identifying Environmental Chemicals Causing Mutations and Cancer | Q34188730 |
| | Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escherichia coli | Q34194565 |
| | Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test | Q34306415 |
| | Formation and human risk of carcinogenic heterocyclic amines formed from natural precursors in meat | Q34428201 |
| | Mutagens in human breast lipid and milk: the search for environmental agents that initiate breast cancer. | Q34580705 |
| | N.A.S. symposium: new evidence as the basis for increased efforts in cancer research | Q34700414 |
| | Complex mixtures of air pollutants: characterizing the cancer risk of polycyclic organic matter | Q34843176 |
| | Bacterial urinary mutagenicity test for monitoring of exposure to genotoxic compounds: a review. | Q34897002 |
| | Bioassay-directed fractionation and chemical identification of mutagens in bioremediated soils | Q34942494 |
| | Toxicology for the twenty-first century | Q34991369 |
| | Genetically-engineered bacteria expressing human enzymes and their use in the study of mutagens and mutagenesis | Q35035524 |
| | Concentration of mutagens from urine by absorption with the nonpolar resin XAD-2: cigarette smokers have mutagenic urine | Q35046473 |
| | Validation and acceptance of new and revised tests: a flexible but transparent process | Q35099284 |
| | Detection of mutagenic activity in cigarette smoke condensates | Q35129622 |
| | Overview, conclusions, and recommendations of the IPCS collaborative study on complex mixtures | Q35308168 |
| | Statistical analysis of the Ames Salmonella/microsome test | Q35384497 |
| | Reproducibility of microbial mutagenicity assays: I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol | Q50209621 |
| | Mutagenicity of azo dyes following metabolism by different reductive/oxidative systems | Q50209687 |
| | Assessing the effect of colony counting methods and genetic drift on ames bioassay results | Q50209732 |
| | A simple modification of the Salmonella liquid-incubation assay Increased sensitivity for detecting mutagens in human urine | Q50211268 |
| | Revised methods for the Salmonella mutagenicity test | Q50211560 |
| | Detection of mutagenic activity in human urine following fried pork or bacon meals | Q50213946 |
| | Analysis of a method for testing azo dyes for mutagenic activity in Salmonella typhimurium in the presence of flavin mononucleotide and hamster liver S9. | Q50214175 |
| | The mutagenicity of diesel-exhaust particle extracts collected under smog-chamber conditions using the Salmonella typhimurium test system | Q50217058 |
| | Modeling the Ames test | Q50217238 |
| | Mutagenicity of volatile anesthetics: halothane | Q50227088 |
| | A simple method for detection and analysis of carcinogenic nitrofuran compounds and their metabolites by combining chromatography and spot mutation tests | Q50227189 |
| | Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes | Q50237965 |
| | Bioassay-directed fractionation of 1-nitropyrene metabolites: generation of mutagrams by coupling reverse-phase HPLC with microsuspension mutagenicity assays | Q50463948 |
| | Are in vitro tests suitable for regulatory use? | Q51810641 |
| | Structure-based methods for predicting mutagenicity and carcinogenicity: are we there yet? | Q52238864 |
| | A mutational assay system using the thymidine kinase locus in mouse lymphoma cells | Q54656411 |
| | Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment | Q57382987 |
| | A Direct Method for Determination of Forward-Mutation Rates in Neurospora crassa | Q59069780 |
| | The Detection of Chemical Mutagens with Enteric Bacteria | Q59666651 |
| | Science and Regulation: Current Impasse and Future Solutions | Q61659565 |
| | The GENE-TOX Program: genetic activity evaluation | Q70797983 |
| | Special microbiological systems. II. Observations on chemical mutagenesis in microorganisms | Q78544966 |
| | History and rationale of genetic toxicity testing: an impersonal, and sometimes personal, view | Q80969742 |
| | A new wave of chemical regulations just ahead? | Q84365417 |
| | Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop | Q84573332 |
| | Fundamental structural alerts to potential carcinogenicity or noncarcinogenicity | Q93646736 |
| | Mutagenic compounds generated from the chlorination of disperse azo-dyes and their presence in drinking water. | Q43341665 |
| | Cancer risk assessment approaches at the FDA/CDER: Is the era of the 2-year bioassay drawing to a close? | Q43734471 |
| | Classification of aminotransferase (C gene) mutants in the histidine operon | Q43837486 |
| | Evidence for the presence of mutagenic arylamines in human breast milk and DNA adducts in exfoliated breast ductal epithelial cells | Q43938566 |
| | Induction of mitotic gene conversion by mutagens | Q44208280 |
| | Science and regulation. New science for chemicals policy | Q44816229 |
| | Mutagen structure and transcriptional response: induction of distinct transcriptional profiles in Salmonella TA100 by the drinking-water mutagen MX and its homologues. | Q45929683 |
| | An update on the genotoxicity and carcinogenicity of marketed pharmaceuticals with reference to in silico predictivity | Q46067853 |
| | Liver microsomal metabolism of aflatoxin B 1 to a reactive derivative toxic to Salmonella typhimurium TA 1530. | Q46428361 |
| | Detection of mutagens in cervical mucus in smokers and nonsmokers. | Q46465412 |
| | Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity | Q46567543 |
| | How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop | Q47581027 |
| | The SOS-LUX-LAC-FLUORO-Toxicity-test on the International Space Station (ISS). | Q47629229 |
| | A novel bacterial reversion and forward mutation assay based on green fluorescent protein | Q47962916 |
| | Statistical methods for the Ames Salmonella assay: a review | Q48629715 |
| | Comparison of the Salmonella/microsome microsuspension assay with the new microplate fluctuation protocol for testing the mutagenicity of environmental samples. | Q50054847 |
| | Comparison of the Ames II and traditional Ames test responses with respect to mutagenicity, strain specificities, need for metabolism and correlation with rodent carcinogenicity | Q50055066 |
| | Bioluminescent Salmonella reverse mutation assay: a screen for detecting mutagenicity with high throughput attributes | Q50069966 |
| | The Salmonella mutagenicity assay in a surface water quality monitoring program based on a 20-year survey | Q50116084 |
| | Mini mutagenicity test: a miniaturized version of the Ames test used in a prescreening assay for point mutagenesis assessment | Q50116093 |
| | The proportions of mutagens among chemicals in commerce | Q50118528 |
| | Comparison of the results of a modified miniscreen and the standard bacterial reverse mutation assays | Q50120038 |
| | Identification of rodent carcinogens and noncarcinogens using genetic toxicity tests: premises, promises, and performance | Q50127761 |
| | Salmonella typhimurium strain TA100 differentiates several classes of carcinogens and mutagens by base substitution specificity | Q50152753 |
| | Specificity and sensitivity of Salmonella typhimurium YG1041 and YG1042 strains possesing elevated levels of both nitroreductase and acetyltransferase activity | Q50162832 |
| | Development of bacterial mutagenicity tests: a view from afar | Q50196580 |
| | Guide for the Salmonella typhimurium/mammalian microsome tests for bacterial mutagenicity | Q50200502 |
| | Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays. | Q50201272 |
| | Vaporization technique to measure mutagenic activity of volatiles organic chemicals in the Ames/Salmonella assay | Q50201961 |
| | Screening complex hazardous wastes for mutagenic activity using a modified version of the TLC/Salmonella assay | Q50203788 |
| | Mutagenicity of the fractionated organic emissions from diesel, cigarette smoke condensate, coke oven, and roofing tar in the Ames assay | Q50206855 |
| | Sources of variability in Ames Salmonella typhimurium tester strains: analysis of the International Collaborative Study on 'genetic drift'. | Q50209135 |
| | Toxicity testing in the 21st century: implications for human health risk assessment | Q35456016 |
| | The significance of mutation in relation to the origin of tumors: a review | Q35530985 |
| | Detection and classification of mutagens: a set of base-specific Salmonella tester strains | Q35925416 |
| | Mutagens in surface waters: a review | Q35968045 |
| | Mutagens in contaminated soil: a review | Q35968056 |
| | The genotoxicity of ambient outdoor air, a review: Salmonella mutagenicity | Q35968062 |
| | The mutagenic hazards of settled house dust: a review. | Q35968068 |
| | An evaluation of 6 short-term tests for detecting organic chemical carcinogens | Q36042322 |
| | Analytical methods in environmental effects-directed investigations of effluents | Q36118846 |
| | An approach to identifying specialized batteries of bioassays for specific classes of chemicals: class analysis using mutagenicity and carcinogenicity relationships and phylogenetic concordance and discordance patterns. 1. Composition and analysis o | Q36465889 |
| | Mammalian cell genetics. II. Chemical induction of specific locus mutations in Chinese hamster cells in vitro | Q36476112 |
| | An evaluation of Salmonella (Ames) test data in the published literature: application of statistical procedures and analysis of mutagenic potency | Q36601927 |
| | An empirical approach to the statistical analysis of mutagenesis data from the Salmonella test | Q36627598 |
| | The history of the stethoscope | Q36652785 |
| | Development and impact of the Gene-Tox-Program, genetic activity profiles, and their computerized data bases | Q36747978 |
| | A review of the mutagenicity and rodent carcinogenicity of ambient air. | Q36798829 |
| | Analytical methods in bioassay-directed investigations of mutagenicity of air particulate material | Q36806065 |
| | Isolation and chemical-structural determination of a novel aromatic amine mutagen in water from the Nishitakase River in Kyoto | Q36888279 |
| | Computational toxicology--a state of the science mini review | Q37027100 |
| | Pragmatic challenges for the vision of toxicity testing in the 21st century in a regulatory context: another Ames test? ...or a new edition of "the Red Book"? | Q37101554 |
| | Characterization and interlaboratory comparison of a gene expression signature for differentiating genotoxic mechanisms | Q37324752 |
| | Improving prediction of chemical carcinogenicity by considering multiple mechanisms and applying toxicogenomic approaches | Q37326001 |
| | Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features | Q37420417 |
| | Predictive models for carcinogenicity and mutagenicity: frameworks, state-of-the-art, and perspectives | Q37468717 |
| | 30 years and a long way into p53 research | Q37589207 |
| | Toxicoproteomics and its application to human health risk assessment | Q37817098 |
| | The DeltauvrB mutations in the Ames strains of Salmonella span 15 to 119 genes. | Q38295833 |
| | The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposures | Q38470614 |
| | The isolation and identification of a new mutagen from fried ground beef: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). | Q38477507 |
| | Detection of mutagenic activity in particulate air pollutants | Q38595056 |
| | Role of metabolism in short-term test development | Q38642972 |
| | Design and implementation of a collaborative study of the mutagenicity of complex mixtures in Salmonella typhimurium | Q39228835 |
| | Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/NTP. | Q39627692 |
| | An analysis by chemical class of Salmonella mutagenicity tests as predictors of animal carcinogenicity | Q39640472 |
| | Target sequences for mutagenesis in Salmonella histidine-requiring mutants. | Q39739092 |
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | bacteria | Q10876 |
| | genotoxicity | Q1009245 |
| | biomedical investigative technique | Q66648976 |
| P304 | page(s) | 1515-1522 | |
| P577 | publication date | 2010-11-01 | |
| P1433 | published in | Environmental Health Perspectives | Q1345904 |
| P1476 | title | The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century | |
| | TheSalmonellaMutagenicity Assay: The Stethoscope of Genetic Toxicology for the 21st Century | |
| P478 | volume | 118 | |