| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1989PNAS...86.5069P |
| P356 | DOI | 10.1073/PNAS.86.13.5069 |
| P932 | PMC publication ID | 297558 |
| P698 | PubMed publication ID | 2787027 |
| P5875 | ResearchGate publication ID | 20369272 |
| P50 | author | Talal A Chatila | Q60539789 |
| P2093 | author name string | S Pahwa | |
| S A Schwartz | |||
| R Pahwa | |||
| N K Day | |||
| R A Good | |||
| N Oyaizu | |||
| R Geha | |||
| C Paradise | |||
| H Slade | |||
| P2860 | cites work | Dissociation in the production of B cell-stimulating factors (BCGF and BCDF) and interleukin 2 by T cells from a common variable immunodeficient patient | Q72390142 |
| Polyclonal and antigen-specific B-Cell responses in patients with common variable immunodeficiency | Q72676354 | ||
| Immunologic effects of interleukin 2 in primary immunodeficiency diseases | Q72785416 | ||
| Inhibiton of IL 2 production after human allogeneic bone marrow transplantation | Q72792621 | ||
| Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen) | Q24296933 | ||
| Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen-receptor complex | Q24300057 | ||
| Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows | Q34734344 | ||
| Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway | Q36252082 | ||
| Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium | Q36265005 | ||
| The functional relationship of the interleukins | Q36343629 | ||
| Structure and expression of a cloned cDNA for human interleukin-2. | Q36603382 | ||
| T-lymphocyte differentiation in vitro in severe combined immunodeficiency. Defects of stem cells | Q37018354 | ||
| Heterogeneity of b lymphocyte differentiation in severe combined immunodeficiency disease | Q37028163 | ||
| Immunodeficiency with defective T-cell response to interleukin 1. | Q37562231 | ||
| Evidence for an interleukin-independent pathway for human lymphocyte activation | Q37614045 | ||
| Functional and molecular aspects of human T lymphocyte activation via T3-Ti and T11 pathways | Q38173938 | ||
| Reconstitution of B and T lymphocyte function in severe combined immunodeficiency disease after transplantation with thymic epithelium | Q39413321 | ||
| Signal transduction in human T lymphocytes | Q39508581 | ||
| T-lymphocyte activation: the role of protein kinase C and the bifurcating inositol phospholipid signal transduction pathway | Q39508598 | ||
| Human interleukin 2: biochemistry, physiology, and possible pathogenetic role in immunodeficiency syndromes | Q39845943 | ||
| Interleukin 2: Biology and biochemistry | Q40145076 | ||
| T-cell growth factor | Q40293133 | ||
| In vitro growth of murine T cells. II. Growth of in vitro sensitized cells cytotoxic for alloantigens | Q40693545 | ||
| Distinct patterns of transmembrane calcium flux and intracellular calcium mobilization after differentiation antigen cluster 2 (E rosette receptor) or 3 (T3) stimulation of human lymphocytes. | Q40922347 | ||
| The structure, function, and expression of interleukin-2 receptors on normal and malignant lymphocytes | Q41998611 | ||
| Long term culture of tumour-specific cytotoxic T cells | Q42799119 | ||
| Molecular cloning and expression of cDNAs for the human interleukin-2 receptor | Q48386792 | ||
| An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein | Q58960509 | ||
| Demonstration of an Intrathymic Defect in a Case of Severe Combined Immunodeficiency Disease | Q66898341 | ||
| Interleukins | Q68876301 | ||
| T lymphocyte subpopulations in high-risk infants: influence of age and blood transfusions | Q69876001 | ||
| The events of primary T cell activation can be staged by use of Sepharose-bound anti-T3 (64.1) monoclonal antibody and purified interleukin 1 | Q69960761 | ||
| A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes | Q70281136 | ||
| Requirement for mitogen, T cell-accessory cell contact, and interleukin 1 in the induction of resting T-cell proliferation | Q70348719 | ||
| Cellular and genetic analyses of IL-2 production and IL-2 receptor expression in a patient with familial T-cell-dominant immunodeficiency | Q70369796 | ||
| Defective B-lymphocyte function in homosexual men in relation to the acquired immunodeficiency syndrome | Q70393452 | ||
| Impaired production of interleukins in patients with cell-mediated immunodeficiencies | Q70985261 | ||
| Relationship between IL 2 synthesis and the proliferative response to PHA in different primary immunodeficiencies | Q72100504 | ||
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | severe combined immunodeficiency | Q1334408 |
| P304 | page(s) | 5069-5073 | |
| P577 | publication date | 1989-07-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Recombinant interleukin 2 therapy in severe combined immunodeficiency disease | |
| P478 | volume | 86 |
| Q73626684 | Alternative antigen receptor (TCR) signaling in T cells derived from ZAP-70-deficient patients expressing high levels of Syk |
| Q90841499 | Biology and regulation of IL-2: from molecular mechanisms to human therapy |
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| Q40681331 | Breakthroughs in the understanding and therapy of primary immunodeficiency. |
| Q67590582 | Cryptococcal osteomyelitis and cellular immunodeficiency associated with interleukin-2 deficiency |
| Q34693494 | Cytokine and cytokine receptor pleiotropy and redundancy |
| Q38216460 | Cytokine immunomodulation for the treatment of infectious diseases: lessons from primary immunodeficiencies |
| Q34572193 | Cytokines and immunodeficiency diseases |
| Q24318910 | Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting |
| Q45779259 | Effect of interleukin 2 on intractable herpes virus infection and chronic eczematoid dermatitis in a patient with Wiskott-Aldrich syndrome |
| Q40426774 | Evaluation of the child with suspected primary immunodeficiency |
| Q37532727 | Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA. |
| Q57059523 | INTERLEUKIN-7 RECEPTOR α CHAIN–DEPENDENT SIGNALING IS REQUIRED FOR T-CELL DEVELOPMENT |
| Q41741343 | Immunodeficiency associated with a nonsense mutation of IKBKB. |
| Q70487790 | Immunomodulatory effects of ultra-low-dose interleukin-2 in cancer patients: a phase-IB study |
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| Q40150624 | Interleukin-2 and granulocyte-macrophage colony-stimulating factor stimulate growth of a virulent strain of Escherichia coli |
| Q35494359 | Low-dose interleukin 2 prevents the development of Epstein-Barr virus (EBV)-associated lymphoproliferative disease in scid/scid mice reconstituted i.p. with EBV-seropositive human peripheral blood lymphocytes |
| Q36316830 | Molecular basis of a multiple lymphokine deficiency in a patient with severe combined immunodeficiency |
| Q68033758 | Novel immune deficiencies: defective transcription of lymphokine genes |
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| Q34344404 | Overexpression of interleukin-2 by a recombinant herpes simplex virus type 1 attenuates pathogenicity and enhances antiviral immunity |
| Q33927983 | Primary combined immunodeficiency resulting from defective transcription of multiple T-cell lymphokine genes. |
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