The kappa-opioid receptor is primarily postsynaptic: combined immunohistochemical localization of the receptor and endogenous opioids

scientific article

The kappa-opioid receptor is primarily postsynaptic: combined immunohistochemical localization of the receptor and endogenous opioids is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1995PNAS...92.5062A
P356DOI10.1073/PNAS.92.11.5062
P932PMC publication ID41848
P698PubMed publication ID7539141
P5875ResearchGate publication ID15660254

P2093author name stringX Lin
S Chakrabarti
J H Lee
M Riedl
H H Loh
P Y Law
M W Wessendorf
U Arvidsson
L Vulchanova
A H Nakano
P2860cites workCloning of a delta opioid receptor by functional expressionQ28213132
Cloning and pharmacological characterization of a rat kappa opioid receptorQ28378330
Molecular cloning and expression of a rat kappa opioid receptorQ28378362
Cloning and functional comparison of kappa and delta opioid receptors from mouse brainQ28378630
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterizationQ30800519
A method for immunofluorescent demonstration of three coexisting neurotransmitters in rat brain and spinal cord, using the fluorophores fluorescein, lissamine rhodamine, and 7-amino-4-methylcoumarin-3-acetic acidQ33259088
Primary structure and functional expression of a guinea pig kappa opioid (dynorphin) receptorQ35196966
kappa-Opioid receptors also increase potassium conductanceQ36705658
Cloning and expression of a cDNA for the rat kappa-opioid receptorQ36741807
Molecular cloning and functional expression of a mu-opioid receptor from rat brain.Q36771913
Cloning and pharmacological characterization of a rat mu opioid receptorQ38314662
A cryptic peptide from the preprothyrotropin-releasing hormone precursor stimulates thyrotropin gene expressionQ41536749
Identification of three separate guanine nucleotide-binding proteins that interact with the delta-opioid receptor in NG108-15 neuroblastoma x glioma hybrid cellsQ41627574
[125I]dynorphin(1-8) produces a similar pattern of kappa-opioid receptor labelling to [3H]dynorphin(1-8) and [3H]etorphine in guinea pig brain: a quantitative autoradiographic studyQ44158509
delta-Opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalinQ44332935
Neuroanatomical localization ofκ1and κ2 opioid receptors in rat and guinea pig brainQ44334863
Quantitative analysis of multiple kappa-opioid receptors by selective and nonselective ligand binding in guinea pig spinal cord: resolution of high and low affinity states of the kappa 2 receptors by a computerized model-fitting techniqueQ44338098
Delta opioid receptor mRNA distribution in the brain: comparison to delta receptor binding and proenkephalin mRNA.Q44338426
Pre- and postsynaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cordQ44338465
Immunofluorescent identification of a delta (delta)-opioid receptor on primary afferent nerve terminals.Q44339459
cDNA cloning and pharmacological characterization of an opioid receptor with high affinities for kappa-subtype-selective ligands.Q44340426
Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain.Q44348080
Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA.Q44697855
Kappa 1 receptor mRNA distribution in the rat CNS: comparison to kappa receptor binding and prodynorphin mRNA.Q48148755
Predominance of the amino-terminal octapeptide fragment of dynorphin in rat brain regionsQ48898838
Characterization of the rat prodynorphin geneQ69453725
Multicolor laser scanning confocal immunofluorescence microscopy: practical application and limitationsQ72623505
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectopioidQ427523
immunohistochemistryQ899285
P1104number of pages5
P304page(s)5062-5066
P577publication date1995-05-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe kappa-opioid receptor is primarily postsynaptic: combined immunohistochemical localization of the receptor and endogenous opioids
P478volume92

Reverse relations

cites work (P2860)
Q3048145030 years of dynorphins--new insights on their functions in neuropsychiatric diseases
Q44352581Agonist-dependent desensitization of the kappa opioid receptor by G protein receptor kinase and beta-arrestin
Q35038090Amygdalar peptidergic circuits regulating noradrenergic locus coeruleus neurons: linking limbic and arousal centers
Q48890551An opioidergic cortical antinociception triggering site in the agranular insular cortex of the rat that contributes to morphine antinociception.
Q44406474Autoradiographic localization of (125)i[Tyr(14)] nociceptin/orphanin FQ binding sites in macaque primate CNS.
Q44347621Both kappa and mu opioid agonists inhibit glutamatergic input to ventral tegmental area neurons
Q42151183Calcitonin receptor-like receptor and receptor activity modifying protein 1 in the rat dorsal horn: localization in glutamatergic presynaptic terminals containing opioids and adrenergic alpha2C receptors
Q44351336Cellular sites for dynorphin activation of kappa-opioid receptors in the rat nucleus accumbens shell
Q44334413Coexistence of kappa- and delta-opioid receptors in rat spinal cord axons
Q48443918Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus: Morphologic evidence of interrelated function within the arcuate nucleus
Q44336063Coexpression of prodynorphin and corticotrophin-releasing hormone in the rat central amygdala: evidence of two distinct endogenous opioid systems in the lateral division
Q44000328Delta opioid inhibition of light-induced phase advances in hamster circadian activity rhythms
Q41023728Differential distribution of alpha2A and alpha2C adrenergic receptor immunoreactivity in the rat spinal cord.
Q37460532Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry
Q30394623Direct targeting of peptidergic amygdalar neurons by noradrenergic afferents: linking stress-integrative circuitry
Q44918606Distinct expression of phosphorylated N-methyl-D-aspartate receptor NR1 subunits by projection neurons and interneurons in the striatum of normal and amphetamine-treated rats
Q44330631Distribution of delta opioid receptor immunoreactivity in the hamster suprachiasmatic nucleus and intergeniculate leaflet
Q40444519Distribution of neuropeptide receptors. New views of peptidergic neurotransmission made possible by antibodies to opioid receptors
Q44347999Down-regulation of mu-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy
Q26997989Drug withdrawal conceptualized as a stressor.
Q41910089Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons
Q39661209Dynorphin acts as a neuromodulator to inhibit itch in the dorsal horn of the spinal cord.
Q35750161Dynorphin and stress-related peptides in rat locus coeruleus: contribution of amygdalar efferents
Q41695359Dynorphin selectively augments the M-current in hippocampal CA1 neurons by an opiate receptor mechanism
Q35928142Dynorphin-containing axons directly innervate noradrenergic neurons in the rat nucleus locus coeruleus.
Q36373891Effects of acute agonist treatment on subcellular distribution of kappa opioid receptor in rat spinal cord
Q44348864Effects of neurotoxins and hindpaw inflammation on opioid receptor immunoreactivities in dorsal root ganglia
Q44330623Effects of sciatic nerve injuries on delta -opioid receptor and substance P immunoreactivities in the superficial dorsal horn of the rat.
Q44348322Endogenous opioid system in developing normal and jimpy oligodendrocytes: mu and kappa opioid receptors mediate differential mitogenic and growth responses
Q44336573Endometriosis Is Associated With a Shift in MU Opioid and NMDA Receptor Expression in the Brain Periaqueductal Gray
Q34074610Enkephalins, dynorphins, and beta-endorphin in the rat dorsal horn: an immunofluorescence colocalization study
Q36930731Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats
Q28569759Expression of cholecystokinin A receptors in neurons innervating the rat stomach and intestine
Q36561843Generation of a KOR-Cre knockin mouse strain to study cells involved in kappa opioid signaling
Q79301190Hyperpolarization of substantia gelatinosa neurons evoked by μ-, κ-, δ1-, and δ2-selective opioids
Q41788624Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone-induced liver damage through inflammation and endoplasmic reticulum stress.
Q40778952Hypothalamic κ-opioid receptor modulates the orexigenic effect of ghrelin
Q44348797Immunohistochemical evidence of down-regulation of mu-opioid receptor after chronic PL-017 in rats
Q41065133Immunolocalization of two mu-opioid receptor isoforms (MOR1 and MOR1B) in the rat central nervous system.
Q28075656Kappa Opioids, Salvinorin A and Major Depressive Disorder
Q44330393Kappa opioid receptor immunoreactivity in the nucleus accumbens and caudate-putamen is primarily associated with synaptic vesicles in axons
Q44333408Kappa opioid receptors are expressed by interneurons in the CA1 area of the rat hippocampus: a correlated light and electron microscopic immunocytochemical study
Q44331087Kappa opioid receptors in rat spinal cord vary across the estrous cycle
Q39992483Kappa opioid receptors regulate stress-induced cocaine seeking and synaptic plasticity
Q42497053Kappa-opioid receptor activation prevents alterations in mesocortical dopamine neurotransmission that occur during abstinence from cocaine
Q44341279Kappa-opioid receptor in the rodent hippocampus: a comparative immunocytochemical study in the rat, guinea pig, hamster and gerbil
Q44335132Localization of kappa opioid receptors in oxytocin magnocellular neurons in the paraventricular and supraoptic nuclei
Q48963556Localization of the somatostatin receptor SST2A in rat brain using a specific anti-peptide antibody.
Q48467322Maximal densities of mu, delta, and kappa receptors are differentially altered by focal cerebral ischaemia in the mouse
Q44340677Morphology and axonal arborization of rat spinal inner lamina II neurons hyperpolarized by mu-opioid-selective agonists
Q73196404NMDA and opioid receptors: their interactions in antinociception, tolerance and neuroplasticity
Q24657309Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance
Q28585437Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
Q43070545Opiate tolerance and dependence: receptors, G-proteins, and antiopiates
Q44332673Opioid induced non-photic phase shifts of hamster circadian activity rhythms
Q43119443Opioids intrinsically inhibit the genesis of mouse cerebellar granule neuron precursors in vitro: differential impact of mu and delta receptor activation on proliferation and neurite elongation
Q44349747Plasticity of Signaling by Spinal Estrogen Receptor α, κ-Opioid Receptor, and Metabotropic Glutamate Receptors over the Rat Reproductive Cycle Regulates Spinal Endomorphin 2 Antinociception: Relevance of Endogenous-Biased Agonism
Q44341626Potential use of early alterations in mu and delta opioid receptors as a predictive index for delayed brain ischemic damage.
Q48934804Preprodynorphin-expressing neurons constitute a large subgroup of somatostatin-expressing GABAergic interneurons in the mouse neocortex
Q41943142Regional, developmental, and cell cycle-dependent differences in mu, delta, and kappa-opioid receptor expression among cultured mouse astrocytes
Q34552064Regulation of Spinal Dynorphin 1-17 Release by Endogenous Pituitary Adenylyl Cyclase-Activating Polypeptide in the Male Rat: Relevance of Excitation via Disinhibition
Q44344453Role of opioid receptors (mu, delta 1, delta 2) in modulating responses of nociceptive neurons in the superficial and deeper dorsal horn of the medulla (trigeminal nucleus caudalis) in the rat.
Q44351738Serotonergic and GABAergic neurons in the medial rostral ventral medulla express kappa-opioid receptor immunoreactivity
Q26770785Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction
Q37604512Sex differences in opioid analgesia, hyperalgesia, tolerance and withdrawal: central mechanisms of action and roles of gonadal hormones
Q35765589Sex differences in sensitivity to the depressive-like effects of the kappa opioid receptor agonist U-50488 in rats
Q37458350Sex differences in the activation of the spinoparabrachial circuit by visceral pain
Q35877147Spinal synthesis of estrogen and concomitant signaling by membrane estrogen receptors regulate spinal κ- and μ-opioid receptor heterodimerization and female-specific spinal morphine antinociception
Q44351620Stimulus-dependent translocation of kappa opioid receptors to the plasma membrane.
Q26999218Stress and VTA synapses: implications for addiction and depression
Q36992606Subcellular targeting of kappa-opioid receptors in the rat nucleus locus coeruleus
Q28354326Synergistic neurotoxicity of opioids and human immunodeficiency virus-1 Tat protein in striatal neurons in vitro
Q34090672The Meissner corpuscle revised: a multiafferented mechanoreceptor with nociceptor immunochemical properties.
Q44330406The kappa opioid receptor and dynorphin co-localize in vasopressin magnocellular neurosecretory neurons in guinea-pig hypothalamus
Q44342177The presence of opioid receptors in rat inner ear.
Q83227620Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry
Q28579996kappa -opioid receptor agonists modulate visceral nociception at a novel, peripheral site of action
Q24315852kappa opioid receptors in human microglia downregulate human immunodeficiency virus 1 expression
Q41132298kappa-opioid receptor expression defines a phenotypically distinct subpopulation of astroglia: relationship to Ca2+ mobilization, development, and the antiproliferative effect of opioids
Q44343360κ-Opioid Agonists Directly Inhibit Midbrain Dopaminergic Neurons

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