| Q37372849 | 1,25-Dihydroxyvitamin D3 and its analogues inhibit acute myelogenous leukemia progenitor proliferation by suppressing interleukin-1beta production |
| Q37389923 | 25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome |
| Q40866852 | A Role for the Inflammasome in Spontaneous Labor at Term |
| Q40079838 | A Role for the Inflammasome in Spontaneous Labor at Term with Acute Histologic Chorioamnionitis |
| Q40071832 | A Role for the Inflammasome in Spontaneous Preterm Labor With Acute Histologic Chorioamnionitis |
| Q71801706 | A Synthetic Inhibitor of Interleukin-lβ Converting Enzyme Prevents Endotoxin-Induced Interleukin-lβ ProductionIn VitroandIn Vivo |
| Q28512900 | A bacterial invasin induces macrophage apoptosis by binding directly to ICE |
| Q46880770 | A comparative study of interleukin-1beta production and p2x7 expression after ATP stimulation by peripheral blood mononuclear cells isolated from rheumatoid arthritis patients and normal healthy controls. |
| Q99207751 | A comprehensive guide to studying inflammasome activation and cell death |
| Q36494115 | A comprehensive map of the toll-like receptor signaling network |
| Q36258539 | A cytosolic serine endopeptidase from Trypanosoma cruzi is required for the generation of Ca2+ signaling in mammalian cells |
| Q28237565 | A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes |
| Q50060450 | A primer on caspase mechanisms |
| Q40932806 | A review on the strategies for the development and application of new anti-arthritic agents |
| Q28388318 | ATP binding by NLRP7 is required for inflammasome activation in response to bacterial lipopeptides |
| Q45172690 | ATP binding cassette transporter ABC1 is required for the release of interleukin-1beta by P2X7-stimulated and lipopolysaccharide-primed mouse Schwann cells |
| Q92688879 | Accumulation of Cytoplasmic DNA Due to ATM Deficiency Activates the Microglial Viral Response System with Neurotoxic Consequences |
| Q37235428 | Activation and regulation of the pattern recognition receptors in obesity-induced adipose tissue inflammation and insulin resistance |
| Q39830626 | Activation of the interleukin-1beta precursor by Treponema denticola: a potential role in chronic inflammatory periodontal diseases |
| Q34384433 | Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme |
| Q34441577 | Acute reactogenicity after intramuscular immunization with recombinant vesicular stomatitis virus is linked to production of IL-1β |
| Q36025116 | Age-related comparisons of evolution of the inflammatory response after intracerebral hemorrhage in rats |
| Q40293566 | Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages |
| Q67738074 | Amino-terminal processing of actins mutagenized at the Cys-1 residue |
| Q52531680 | An interleukin-1 loop is induced in human skin fibroblasts upon stress relaxation in a three-dimensional collagen gel but is not involved in the up-regulation of matrix metalloproteinase 1. |
| Q36366579 | Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death |
| Q56374083 | Apoptosis Activity of the Mouse Macrophage Cell Line J774A.1 Infected with a Recombinant BCG consisting the C-Terminus of Merozoite Surface Protein-1 of |
| Q89685901 | Autoimmune inner ear disease patient-associated 28-kDa proinflammatory IL-1β fragment results from caspase-7-mediated cleavage in vitro |
| Q33762651 | Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation |
| Q24531784 | Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9 |
| Q34505406 | Caspase-1 and IL-1β processing in a teleost fish |
| Q34044187 | Caspase-1: an integral regulator of innate immunity |
| Q38024075 | Caspase-1: is IL-1 just the tip of the ICEberg? |
| Q34344861 | Caspase-1: the inflammasome and beyond |
| Q45118839 | Caspase-1zeta, a new splice variant of the caspase-1 gene |
| Q42169749 | Caspases |
| Q38230622 | Caspases as the key effectors of inflammatory responses against bacterial infection |
| Q89526718 | Caspases in Cell Death, Inflammation, and Gasdermin-Induced Pyroptosis |
| Q24530218 | Caspases: the executioners of apoptosis |
| Q52671863 | Cell-Free Assay for Inflammasome Activation. |
| Q62817572 | Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis |
| Q35833800 | Chlamydia muridarum infection of macrophages elicits bactericidal nitric oxide production via reactive oxygen species and cathepsin B. |
| Q44859503 | Chronological study of cytokine transcription in the spleen and lung of chickens after vaccination with serotype 1 Marek's disease vaccines. |
| Q36483726 | Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes |
| Q24315820 | Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities |
| Q41365438 | Construction and expression in tumor cells of a recombinant vaccinia virus encoding human interleukin-1 beta |
| Q97067692 | Contribution of Aberrant Toll Like Receptor Signaling to the Pathogenesis of Myelodysplastic Syndromes |
| Q26776532 | Converging roles of caspases in inflammasome activation, cell death and innate immunity |
| Q38180799 | Cytokine networking of innate immunity cells: a potential target of therapy. |
| Q91868242 | Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage |
| Q92623270 | Dengue Virus M Protein Promotes NLRP3 Inflammasome Activation To Induce Vascular Leakage in Mice |
| Q39698331 | Differential cytokine responses following Marek's disease virus infection of chickens differing in resistance to Marek's disease |
| Q43675654 | Differential effects of caspase-1/interleukin-1beta-converting enzyme on acinar cell necrosis and apoptosis in severe acute experimental pancreatitis |
| Q37721559 | Differential roles of caspase-1 and caspase-11 in infection and inflammation |
| Q92971145 | Divergent Roles for the IL-1 Family in Gastrointestinal Homeostasis and Inflammation |
| Q41729429 | Dual mechanisms of apoptosis induction by cytotoxic lymphocytes. |
| Q71942217 | EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. III. Biochemical properties of EI-1511-3, -5 and EI-1625-2 |
| Q57305797 | Elevated levels of interleukin-1?-converting enzyme and caspase-cleaved cytokeratin-18 in acute myocardial infarction |
| Q33815859 | Endogenous liver carcinogenesis in the rat. |
| Q28547711 | Enteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome Activation |
| Q35187869 | Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia |
| Q35186914 | Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: a link between the inflammasome and parturition |
| Q60687741 | Evidence that increases of mitochondrial immunoreactive IL-1β by HIV-1 gp120 implicatein situcleavage of pro-IL-1β in the neocortex of rat |
| Q41126145 | Evolutionary conservation of a genetic pathway of programmed cell death |
| Q47855030 | Expression, refolding, and autocatalytic proteolytic processing of the interleukin-1 beta-converting enzyme precursor |
| Q50134116 | Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1. |
| Q41484408 | Factors affecting IL-1-mediated collagen metabolism by fibroblasts and the pathogenesis of periodontal disease: a review of the literature |
| Q36831484 | Functional characterization of the prodomain of interleukin-1beta-converting enzyme |
| Q90046211 | Gasdermin D: in vivo evidence of pyroptosis in spontaneous labor at term |
| Q41711827 | Gene expression, biological effects and clinical aspects of lymphokines |
| Q42451967 | Gingival and dermal fibroblasts produce interleukin‐1β converting enzyme and interleukin‐1β but not interleukin‐18 even after stimulation with lipopolysaccharide |
| Q42525902 | Gingival fibroblast cytokine profiles in Actinobacillus actinomycetemcomitans-associated periodontitis |
| Q40576695 | Gold sodium thiomalate and chloroquine inhibit cytokine production in monocytic THP-1 cells through distinct transcriptional and posttranslational mechanisms |
| Q36364802 | Granzyme A is an interleukin 1 beta-converting enzyme |
| Q45785971 | Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A. |
| Q40494735 | HMGB1 Induces an Inflammatory Response in the Chorioamniotic Membranes That Is Partially Mediated by the Inflammasome |
| Q33538552 | How bacteria initiate inflammation: aspects of the emerging story |
| Q41990044 | How inflammasomes inform adaptive immunity |
| Q37887598 | How pathogen-derived cysteine proteases modulate host immune responses |
| Q40512221 | Human keratinocytes produce but do not process pro-interleukin-1 (IL-1) beta. Different strategies of IL-1 production and processing in monocytes and keratinocytes |
| Q41062062 | Hyperglycemic levels of glucose inhibit interleukin 1 release from RAW 264.7 murine macrophages by activation of protein kinase C. |
| Q71964256 | IL-1β regulates rat mesangial cyclooxygenase II gene expression by tyrosine phosphorylation |
| Q24324859 | Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases |
| Q33702165 | Identification of calcium-activated neutral protease as a processing enzyme of human interleukin 1 alpha |
| Q35816841 | Immune and inflammatory processes in cutaneous tissues. Mechanisms and speculations |
| Q32062368 | Immunohistochemical investigation of caspase-1 and effect of caspase-1 inhibitor in delayed neuronal death after transient cerebral ischemia |
| Q48120804 | Immunohistochemical localization of interleukin-1beta, interleukin-1 receptor antagonist and interleukin-1beta converting enzyme/caspase-1 in the rat brain after peripheral administration of kainic acid |
| Q48060946 | In silico and In vitro evaluation of the anti-inflammatory potential of Centratherum punctatum Cass-A. |
| Q47237229 | In vivo evidence of inflammasome activation during spontaneous labor at term |
| Q40343166 | Increased cyclic AMP levels enhance IL-1 alpha and IL-1 beta mRNA expression and protein production in human myelomonocytic cell lines and monocytes |
| Q28372886 | Induction of apoptosis by dexrazoxane (ICRF-187) through caspases in the absence of c-jun expression and c-Jun NH2-terminal kinase 1 (JNK1) activation in VM-26-resistant CEM cells |
| Q73165439 | Induction of apoptosis by penta-O-galloyl-beta-D-glucose through activation of caspase-3 in human leukemia HL-60 cells |
| Q41071828 | Induction of interleukin-1 beta-converting enzyme (ICE) in murine microglia by lipopolysaccharide |
| Q61607471 | Inflammasome activation during spontaneous preterm labor with intra-amniotic infection or sterile intra-amniotic inflammation |
| Q53303724 | Inflammasome and cardiovascular diseases |
| Q40319524 | Inflammasome assembly in the chorioamniotic membranes during spontaneous labor at term |
| Q58202560 | Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis |
| Q28263855 | Inflammatory caspases and inflammasomes: master switches of inflammation |
| Q28578834 | Inhibition of caspase-1 in rat brain reduces spontaneous nonrapid eye movement sleep and nonrapid eye movement sleep enhancement induced by lipopolysaccharide |
| Q61844917 | Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes† |
| Q35028627 | Innate immune recognition of francisella tularensis: activation of type-I interferons and the inflammasome |
| Q33214021 | Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity. |
| Q36133301 | Interleukin 1 beta (IL-1 beta) processing in murine macrophages requires a structurally conserved homologue of human IL-1 beta converting enzyme |
| Q36363516 | Interleukin 1 beta propeptide is detected intracellularly and extracellularly when human monocytes are stimulated with LPS in vitro |
| Q24315035 | Interleukin 1 is processed and released during apoptosis |
| Q28571336 | Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism |
| Q40806560 | Interleukin-1 beta converting enzyme requires oligomerization for activity of processed forms in vivo |
| Q36278873 | Interleukin-1 beta converting enzyme: a novel cysteine protease required for IL-1 beta production and implicated in programmed cell death |
| Q41326561 | Interleukin-1 beta secretion. A possible multistep process that is regulated in a cell type-specific manner |
| Q74746989 | Interleukin-1 receptors: cloning studies and role in central nervous system disorders |
| Q40860960 | Interleukin-1: therapeutic potential for solid tumors |
| Q73747954 | Interleukin-1beta immunoreactivity in identified neurons of the rat magnocellular neurosecretory system: evidence for activity-dependent release |
| Q35610761 | Interleukin-1β Level Is Increased in Vitreous of Patients with Neovascular Age-Related Macular Degeneration (nAMD) and Polypoidal Choroidal Vasculopathy (PCV). |
| Q61844901 | Intra-amniotic inflammation induces preterm birth by activating the NLRP3 inflammasome† |
| Q39307144 | Involvement of inflammasome activation in lipopolysaccharide-induced mice depressive-like behaviors |
| Q45749035 | Involvement of interleukin-1beta in the mechanism of human immunodeficiency virus type 1 (HIV-1) recombinant protein gp120-induced apoptosis in the neocortex of rat. |
| Q36931182 | Is there value in plasma cytokine measurements in patients with severe trauma and sepsis? |
| Q38557771 | Journey of cystatins from being mere thiol protease inhibitors to at heart of many pathological conditions |
| Q34792751 | Kallikrein cascade and cytokines in inflamed joints |
| Q60068379 | Key mediator takes shape |
| Q39520445 | Lipopolysaccharide of Burkholderia cepacia and its unique character to stimulate murine macrophages with relative lack of interleukin-1beta-inducing ability |
| Q41737527 | Lymphocyte granule-mediated cell death. |
| Q92575076 | MMPs and ADAMs in neurological infectious diseases and multiple sclerosis |
| Q37088323 | Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways |
| Q44471588 | Maturation and release of interleukin-1beta by lipopolysaccharide-primed mouse Schwann cells require the stimulation of P2X7 receptors |
| Q50027054 | Mechanical Activation of Adipose Tissue and Derived Mesenchymal Stem Cells: Novel Anti-Inflammatory Properties |
| Q36366486 | Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone. |
| Q47653328 | Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats. |
| Q36593977 | Modulation of the bovine trophoblastic innate immune response by Brucella abortus. |
| Q24329060 | Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases |
| Q28572533 | Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor |
| Q39277467 | Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases. |
| Q28388472 | MyD88 dependence of beryllium-induced dendritic cell trafficking and CD4⁺ T-cell priming |
| Q36912187 | NALP inflammasomes: a central role in innate immunity. |
| Q34846646 | Nedd8 regulates inflammasome-dependent caspase-1 activation |
| Q28144013 | Neuronal interleukin-16 (NIL-16): a dual function PDZ domain protein |
| Q35031950 | New insights into the mechanism of IL-1beta maturation |
| Q41168225 | Nitric oxide regulates interleukin 1 bioactivity released from murine macrophages |
| Q90175984 | No Major Effect of Innate Immune Genetics on Acute Kidney Rejection in the First 2 Weeks Post-Transplantation |
| Q64238053 | Non-canonical Inflammasome-Mediated IL-1β Production by Primary Endometrial Epithelial and Stromal Fibroblast Cells Is NLRP3 and Caspase-4 Dependent |
| Q39100969 | Noncanonical inflammasomes: Antimicrobial defense that does not play by the rules. |
| Q36180587 | Overexpression of Caspase-1 in adenocarcinoma of pancreas and chronic pancreatitis |
| Q36619620 | Overexpression of IL-1ra gene up-regulates interleukin-1beta converting enzyme (ICE) gene expression: possible mechanism underlying IL-1beta-resistance of cancer cells |
| Q53765723 | Overexpression of caspase-1 in pancreatic disorders: implications for a function besides apoptosis. |
| Q33615261 | Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling |
| Q33682659 | Pharmacodynamics and toxicodynamics of drug action: signaling in cell survival and cell death |
| Q40929570 | Pharmacological characterization of ATP- and LPS-induced IL-1beta release in human monocytes |
| Q40806357 | Potassium-inhibited processing of IL-1 beta in human monocytes |
| Q45877926 | Prevention of murine breast cancer by vaccination with tumor cells modified by cytokine-producing recombinant vaccinia viruses |
| Q46334027 | Probiotics enhance pancreatic glutathione biosynthesis and reduce oxidative stress in experimental acute pancreatitis |
| Q78043823 | Production and characterization of an in vitro engineered human oral mucosa |
| Q41985754 | Production, purification, and crystallization of human interleukin-1 beta converting enzyme derived from an Escherichia coli expression system |
| Q39569992 | Proteolytic activation of the interleukin-1beta precursor by Candida albicans. |
| Q41417507 | Purification of a 24-kD protease from apoptotic tumor cells that activates DNA fragmentation |
| Q38828978 | Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1β Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells |
| Q41133709 | Reduced incidence and severity of antigen-induced autoimmune diseases in mice lacking interferon regulatory factor-1. |
| Q70694686 | Reduced secretion of IL-1 beta by peritoneal cells from patients on continuous ambulatory peritoneal dialysis |
| Q43108074 | Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain |
| Q36946923 | Regulatory T Cells Contribute to the Inhibition of Radiation-Induced Acute Lung Inflammation via Bee Venom Phospholipase A₂ in Mice. |
| Q54660924 | Retinal pigment epithelial cells produce interleukin-1 beta and granulocyte-macrophage colony-stimulating factor in response to interleukin-1 alpha. |
| Q28379199 | Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation |
| Q36268704 | Review: Transcriptional and post-transcriptional regulation of interleukin 1 gene expression |
| Q53985837 | Role of CD95-activated caspase-1 processing of IL-1beta in TCR-mediated proliferation of HIV-infected CD4(+) T cells. |
| Q41610123 | Role of cytokines in sepsis. |
| Q41404410 | Role of interleukin-1 beta converting enzyme (ICE) in acute myelogenous leukemia cell proliferation and programmed cell death |
| Q40860376 | Role of interleukin-1 inhibitory molecules in therapy of acute and chronic myelogenous leukemia |
| Q24676746 | Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis |
| Q36664121 | Roles of heat-shock protein 70 in protecting against intestinal mucosal damage |
| Q24301821 | S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells |
| Q36368780 | Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model |
| Q34469766 | Salmonella-induced macrophage death: the role of caspase-1 in death and inflammation. |
| Q70865393 | Secretion of human monocyte mature IL-1 beta: optimization of culture conditions and inhibition by ICE inhibitors |
| Q37361913 | Selective induction of apoptosis in Hep 3B cells by topoisomerase I inhibitors: evidence for a protease-dependent pathway that does not activate cysteine protease P32. |
| Q35836079 | Small Molecule Active Site Directed Tools for Studying Human Caspases |
| Q35837150 | Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection |
| Q47178842 | Spontaneous Preterm Birth: Advances Toward the Discovery of Genetic Predisposition |
| Q74570079 | Stimulation of interleukin-1 beta production of human dental pulp cells by Porphyromonas endodontalis lipopolysaccharide |
| Q41510713 | Structure and function of interleukin-1 beta converting enzyme. |
| Q27730830 | Structure and mechanism of interleukin-1 beta converting enzyme |
| Q36742286 | Substrate and inhibitor-induced dimerization and cooperativity in caspase-1 but not caspase-3. |
| Q58764105 | Subversion of Cytokine Networks by Viruses |
| Q40621226 | Suppressor mechanism of serum thymic factor on tumor necrosis factor-α-induced apoptosis in the mouse pancreatic β-cell line |
| Q38334213 | Synaptotagmin-1 is required for fibroblast growth factor-1 release |
| Q24292337 | The ATP binding cassette transporter A1 contributes to the secretion of interleukin 1beta from macrophages but not from monocytes |
| Q47258910 | The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice |
| Q29616026 | The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance |
| Q92358046 | The NLRP3 inflammasome: a new player in neurological diseases |
| Q33768462 | The P2Z/P2X7 receptor of microglial cells: a novel immunomodulatory receptor. |
| Q40700265 | The clinical significance of caspase regulation in acute leukemia |
| Q34167756 | The cytokine response to physical activity and training |
| Q24642151 | The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment |
| Q37648485 | The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte-macrophage differentiation |
| Q24305136 | The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta |
| Q42943119 | The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy |
| Q22254013 | The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells |
| Q28344080 | Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis |
| Q28591179 | Tissue kallikrein mK13 is a candidate processing enzyme for the precursor of interleukin-1beta in the submandibular gland of mice |
| Q78631233 | Tissue structure, and IL-1beta, IL-8, and TNF-alpha secretions after contact by engineered human oral mucosa with dentifrices |
| Q48513210 | Transient global forebrain ischemia induces a prolonged expression of the caspase-3 mRNA in rat hippocampal CA1 pyramidal neurons |
| Q67545387 | Transthyretin is an inhibitor of monocyte and endothelial cell interleukin-1 production |
| Q58617004 | Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages |
| Q28639902 | Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway |
| Q39812677 | Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death. |