Zinc and regulation of inflammatory cytokines: implications for cardiometabolic disease

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Zinc and regulation of inflammatory cytokines: implications for cardiometabolic disease is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3390/NU4070676
P932PMC publication ID3407988
P698PubMed publication ID22852057
P5875ResearchGate publication ID230593360

P50authorMeika FosterQ123230816
Samir SammanQ89032280
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Selected major risk factors and global and regional burden of diseaseQ29614888
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Reduced production of immunoregulatory cytokines in vitamin A- and zinc-deficient Indonesian infantsQ30831836
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Nitric oxide-mediated protection of endothelial cells from hydrogen peroxide is mediated by intracellular zinc and glutathioneQ33405708
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Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agentQ33849338
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Functions of zinc in signaling, proliferation and differentiation of mammalian cellsQ34520020
Zinc metabolism and homeostasis: the application of tracer techniques to human zinc physiologyQ34520044
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic isletsQ34796756
A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admissionQ34983983
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Zinc deficiency: changes in cytokine production and T-cell subpopulations in patients with head and neck cancer and in noncancer subjectsQ73018529
In vitro effect of zinc on superoxide anion production by polymorphonuclear leukocytes of diabetic patientsQ50106147
Oral zinc therapy in diabetic neuropathy.Q51550623
Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite.Q52574107
Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury.Q52888343
Increased number of islet-associated macrophages in type 2 diabetes.Q53545508
Zinc deficiency and IL-6 -174G/C polymorphism in old people from different European countries: effect of zinc supplementation. ZINCAGE study.Q54773095
Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc statusQ56997105
Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammationQ59628878
Alterations in zinc homeostasis underlie endothelial cell death induced by oxidative stress from acute exposure to hydrogen peroxideQ64377538
Increase in the glucosylated form of erythrocyte Cu-Zn-superoxide dismutase in diabetes and close association of the nonenzymatic glucosylation with the enzyme activityQ68983896
Decreased natural killer cell activity in patients with zinc deficiency with sickle cell diseaseQ70051561
Dietary versus cellular zinc: the antioxidant paradoxQ70613250
Is zinc deficiency a risk factor for atherosclerosis?Q35646081
Role of Toll-like receptor 4 in the initiation and progression of atherosclerotic diseaseQ35775318
Hyperglycemia-induced oxidative stress in diabetic complications.Q35838309
The neurobiology of zinc in health and diseaseQ36126098
NADPH oxidases in cardiovascular health and diseaseQ36505570
The effect of zinc supplementation in humans on plasma lipids, antioxidant status and thrombogenesisQ36582037
Zinc: mechanisms of host defenseQ36798067
TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common themeQ37184150
Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.Q37245109
Mammalian zinc transporters: nutritional and physiologic regulationQ37463198
Cytokine production by islets in health and diabetes: cellular origin, regulation and function.Q37680187
Zinc and redox signaling: perturbations associated with cardiovascular disease and diabetes mellitusQ37766871
The significance of zinc for humoral and cellular immunity.Q38263557
Zinc induces chemokine and inflammatory cytokine release from human promonocytesQ39462943
Zinc, cadmium and nickel increase the activation of NF-κB and the release of cytokines from THP-1 monocytic cellsQ39490243
Polymorphonuclear leukocyte-mediated cell and tissue injury: oxygen metabolites and their relations to human diseaseQ39496586
Zinc-suppressed inflammatory cytokines by induction of A20-mediated inhibition of nuclear factor-κB.Q39638233
Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitriteQ39737681
Zinc deficiency induces membrane barrier damage and increases neutrophil transmigration in Caco-2 cellsQ39948795
Zinc-dependent suppression of TNF-alpha production is mediated by protein kinase A-induced inhibition of Raf-1, I kappa B kinase beta, and NF-kappa B.Q40085254
Correction of interleukin-2 gene expression by in vitro zinc addition to mononuclear cells from zinc-deficient human subjects: a specific test for zinc deficiency in humansQ40197767
Zn2+-induced NF-kappaB-dependent transcriptional activity involves site-specific p65/RelA phosphorylationQ40226293
Evidence for reprogramming global gene expression during zinc deficiency in the HUT-78 cell lineQ40230943
Toxic effect of zinc on NF-kappaB, IL-2, IL-2 receptor alpha, and TNF-alpha in HUT-78 (Th(0)) cellsQ40239922
Zinc-buffering capacity of a eukaryotic cell at physiological pZn.Q40240984
Zinc-mediated inhibition of cyclic nucleotide phosphodiesterase activity and expression suppresses TNF-alpha and IL-1 beta production in monocytes by elevation of guanosine 3',5'-cyclic monophosphateQ40370277
Involvement of activation of NADPH oxidase and extracellular signal-regulated kinase (ERK) in renal cell injury induced by zincQ40414854
Antioxidant effect of zinc in humansQ40510598
Neutrophil interactions with endothelium and platelets: possible role in the development of cardiovascular injuryQ40521926
Zinc uptake system (znuA locus) of Brucella abortus is essential for intracellular survival and virulence in miceQ40524195
Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam StudyQ40603438
Zinc inhibits interleukin-1-dependent T cell stimulationQ41079200
The immunobiology of zincQ41654433
The nuclear factor kappa-B signaling pathway participates in dysregulation of vascular smooth muscle cells in vitro and in human atherosclerosisQ42439767
Effects of zinc on plasma lipoprotein cholesterol concentrations in humans: a meta-analysis of randomised controlled trialsQ43208046
Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stressQ43956864
Immune functions are maintained in healthy men with low zinc intake.Q45967091
Distinctive modulation of inflammatory and metabolic parameters in relation to zinc nutritional status in adult overweight/obese subjects.Q46019512
Zinc deficiency in Mexican American children: influence of zinc and other micronutrients on T cells, cytokines, and antiinflammatory plasma proteinsQ46325482
Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patientsQ46449826
Attenuation of interferon-gamma mRNA expression in activated Jurkat T cells by exogenous zinc via down-regulation of the calcium-independent PKC-AP-1 signaling pathwayQ46549769
DFT-based molecular modeling and vibrational study of the La(III) complex of 3,3'-(benzylidene)bis(4-hydroxycoumarin).Q46744618
Zinc at pharmacologic concentrations affects cytokine expression and induces apoptosis of human peripheral blood mononuclear cellsQ46940436
Effect of zinc supplementation on immune and inflammatory responses in pediatric patients with shigellosisQ48014900
Endotoxin induction of murine metallothionein gene expressionQ48898320
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectpeptideQ172847
inorganic compoundQ190065
atherosclerosisQ12252367
cytokineQ212354
diabetesQ12206
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)676-694
P577publication date2012-07-01
2012-07-04
P1433published inNutrientsQ7070485
P1476titleZinc and regulation of inflammatory cytokines: implications for cardiometabolic disease
P478volume4

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