review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1037897301 |
P356 | DOI | 10.1038/SJ.ONC.1204093 |
P698 | PubMed publication ID | 11426651 |
P5875 | ResearchGate publication ID | 11913347 |
P2093 | author name string | Crooke ST | |
P2860 | cites work | Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII | Q22004015 |
Molecular cloning and expression of cDNA for human RNase H. | Q32086235 | ||
Phase I evaluation of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C-alpha, in patients with advanced cancer | Q33330493 | ||
Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma | Q33332247 | ||
Properties of cloned and expressed human RNase H1. | Q33874988 | ||
Morpholino antisense oligomers: the case for an RNase H-independent structural type | Q33901587 | ||
Novel mechanisms for antisense-mediated regulation of gene expression | Q33916092 | ||
Antisense oligonucleotides as a tool for gene functionalization and target validation | Q33916097 | ||
Molecular mechanisms of action of antisense drugs | Q33916100 | ||
A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides | Q33916114 | ||
Human Bcl-2 antisense therapy for lymphomas | Q33916124 | ||
2'-carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation | Q33916133 | ||
Antisense properties of peptide nucleic acid | Q33916142 | ||
Conformationally restricted carbohydrate-modified nucleic acids and antisense technology | Q33916146 | ||
The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells | Q33957440 | ||
Therapeutic applications of oligonucleotides | Q35153579 | ||
Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides | Q35230003 | ||
Biologic and therapeutic significance of MYB expression in human melanoma | Q35237618 | ||
Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotide | Q35237895 | ||
Site specific enzymatic cleavage of RNA | Q35758603 | ||
Purification and characterization of human ribonuclease HII. | Q35873753 | ||
Oligodeoxynucleotides enhance lipopolysaccharide-stimulated synthesis of tumor necrosis factor: dependence on phosphorothioate modification and reversal by heparin. | Q36437931 | ||
Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice | Q37585661 | ||
Transport of phosphorothioate oligonucleotides in kidney: Implications for molecular therapy | Q38296093 | ||
Characterization of Binding Sites, Extent of Binding, and Drug Interactions of Oligonucleotides with Albumin | Q38300743 | ||
Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets | Q38320249 | ||
Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element | Q38334658 | ||
Cleavage of single strand RNA adjacent to RNA-DNA duplex regions by Escherichia coli RNase H1. | Q38342120 | ||
Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation | Q38343811 | ||
The Influence of Antisense Oligonucleotide-induced RNA Structure on Escherichia coli RNase H1 Activity | Q38344190 | ||
Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids | Q38349308 | ||
Highly efficient chemical synthesis of 2'-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases. | Q40449252 | ||
Alpha-DNA.IX: Parallel annealing of alpha-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription. | Q40451200 | ||
Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substrates | Q40537453 | ||
RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds | Q40539121 | ||
Complementary oligodeoxynucleotide mediated inhibition of tobacco mosaic virus RNA translation in vitro | Q40546194 | ||
Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A). | Q40629963 | ||
Antisense oligonucleotides as therapeutic agents--is the bullet really magical? | Q40834751 | ||
Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexes | Q41908017 | ||
Implication of RNA structure on antisense oligonucleotide hybridization kinetics | Q45059437 | ||
A pharmacokinetic evaluation of 14C-labeled afovirsen sodium in patients with genital warts. | Q52871121 | ||
Interferon Induction Increased through Chemical Modification of a Synthetic Polyribonucleotide | Q54685574 | ||
BCL-2 antisense therapy in patients with non-Hodgkin lymphoma | Q61868294 | ||
Therapeutic Applications of Oligonucleotides | Q68156172 | ||
Uptake characteristics of oligonucleotides in the isolated rat liver perfusion system | Q71773051 | ||
Evaluating the mechanism of action of antiproliferative antisense drugs | Q73774527 | ||
P433 | issue | 56 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | chemotherapy | Q974135 |
P304 | page(s) | 6651-6659 | |
P577 | publication date | 2000-12-01 | |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Potential roles of antisense technology in cancer chemotherapy | |
P478 | volume | 19 |