Potential roles of antisense technology in cancer chemotherapy

scientific article

Potential roles of antisense technology in cancer chemotherapy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1037897301
P356DOI10.1038/SJ.ONC.1204093
P698PubMed publication ID11426651
P5875ResearchGate publication ID11913347

P2093author name stringCrooke ST
P2860cites workCloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HIIQ22004015
Molecular cloning and expression of cDNA for human RNase H.Q32086235
Phase I evaluation of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C-alpha, in patients with advanced cancerQ33330493
Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphomaQ33332247
Properties of cloned and expressed human RNase H1.Q33874988
Morpholino antisense oligomers: the case for an RNase H-independent structural typeQ33901587
Novel mechanisms for antisense-mediated regulation of gene expressionQ33916092
Antisense oligonucleotides as a tool for gene functionalization and target validationQ33916097
Molecular mechanisms of action of antisense drugsQ33916100
A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotidesQ33916114
Human Bcl-2 antisense therapy for lymphomasQ33916124
2'-carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugationQ33916133
Antisense properties of peptide nucleic acidQ33916142
Conformationally restricted carbohydrate-modified nucleic acids and antisense technologyQ33916146
The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cellsQ33957440
Therapeutic applications of oligonucleotidesQ35153579
Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotidesQ35230003
Biologic and therapeutic significance of MYB expression in human melanomaQ35237618
Suppression of Philadelphia1 leukemia cell growth in mice by BCR-ABL antisense oligodeoxynucleotideQ35237895
Site specific enzymatic cleavage of RNAQ35758603
Purification and characterization of human ribonuclease HII.Q35873753
Oligodeoxynucleotides enhance lipopolysaccharide-stimulated synthesis of tumor necrosis factor: dependence on phosphorothioate modification and reversal by heparin.Q36437931
Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in miceQ37585661
Transport of phosphorothioate oligonucleotides in kidney: Implications for molecular therapyQ38296093
Characterization of Binding Sites, Extent of Binding, and Drug Interactions of Oligonucleotides with AlbuminQ38300743
Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targetsQ38320249
Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR elementQ38334658
Cleavage of single strand RNA adjacent to RNA-DNA duplex regions by Escherichia coli RNase H1.Q38342120
Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formationQ38343811
The Influence of Antisense Oligonucleotide-induced RNA Structure on Escherichia coli RNase H1 ActivityQ38344190
Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybridsQ38349308
Highly efficient chemical synthesis of 2'-O-methyloligoribonucleotides and tetrabiotinylated derivatives; novel probes that are resistant to degradation by RNA or DNA specific nucleases.Q40449252
Alpha-DNA.IX: Parallel annealing of alpha-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription.Q40451200
Number and distribution of methylphosphonate linkages in oligodeoxynucleotides affect exo- and endonuclease sensitivity and ability to form RNase H substratesQ40537453
RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bondsQ40539121
Complementary oligodeoxynucleotide mediated inhibition of tobacco mosaic virus RNA translation in vitroQ40546194
Phase I clinical/pharmacokinetic and pharmacodynamic trial of the c-raf-1 antisense oligonucleotide ISIS 5132 (CGP 69846A).Q40629963
Antisense oligonucleotides as therapeutic agents--is the bullet really magical?Q40834751
Kinetic characteristics of Escherichia coli RNase H1: cleavage of various antisense oligonucleotide-RNA duplexesQ41908017
Implication of RNA structure on antisense oligonucleotide hybridization kineticsQ45059437
A pharmacokinetic evaluation of 14C-labeled afovirsen sodium in patients with genital warts.Q52871121
Interferon Induction Increased through Chemical Modification of a Synthetic PolyribonucleotideQ54685574
BCL-2 antisense therapy in patients with non-Hodgkin lymphomaQ61868294
Therapeutic Applications of OligonucleotidesQ68156172
Uptake characteristics of oligonucleotides in the isolated rat liver perfusion systemQ71773051
Evaluating the mechanism of action of antiproliferative antisense drugsQ73774527
P433issue56
P407language of work or nameEnglishQ1860
P921main subjectchemotherapyQ974135
P304page(s)6651-6659
P577publication date2000-12-01
P1433published inOncogeneQ1568657
P1476titlePotential roles of antisense technology in cancer chemotherapy
P478volume19