Role of thrombin and thromboxane A2 in reocclusion following coronary thrombolysis with tissue-type plasminogen activator

scientific article

Role of thrombin and thromboxane A2 in reocclusion following coronary thrombolysis with tissue-type plasminogen activator is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1989PNAS...86.7585F
P356DOI10.1073/PNAS.86.19.7585
P932PMC publication ID298110
P698PubMed publication ID2508092
P5875ResearchGate publication ID20648234

P2093author name stringD J Fitzgerald
G A Fitzgerald
P2860cites workThrombin activity of fibrin thrombi and soluble plasmic derivativesQ72788151
[Rapid physiological coagulation method in determination of fibrinogen]Q74515389
Isolation and characterization of a high molecular weight glycoprotein from human blood plateletsQ22009134
Coronary vascular occlusion mediated via thromboxane A2-prostaglandin endoperoxide receptor activation in vivoQ34521034
Interaction of coagulation factor Xa with human plateletsQ35053163
Protection of factor Xa from neutralization by the heparin-antithrombin complexQ35207027
Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosisQ35593380
Platelet protein phosphorylation, elevation of cytosolic calcium, and inositol phospholipid breakdown in platelet activation induced by plasminQ35807759
Monoclonal antibody against the platelet glycoprotein (GP) IIb/IIIa receptor prevents coronary artery reocclusion after reperfusion with recombinant tissue-type plasminogen activator in dogsQ35812008
Tissue plasminogen activatorQ39605345
Thrombolytic therapy: current status (1).Q39640542
Thrombin active-site regionsQ39746923
Thromboxane a2: biosynthesis and effects on plateletsQ40113741
Increased thromboxane biosynthesis during coronary thrombolysis. Evidence that platelet activation and thromboxane A2 modulate the response to tissue-type plasminogen activator in vivoQ41261399
Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettesQ41429832
Inhibition of cyclic flow variations in stenosed canine coronary arteries by thromboxane A2/prostaglandin H2 receptor antagonistsQ41452584
The multiple complexes formed by the interaction of platelet factor 4 with heparinQ42165472
The activation of prothrombin. II. Partial reactions, physical and chemical characterization of the intermediates of activation.Q47956980
The Purification and Mechanism of Action of Human Antithrombin-Heparin CofactorQ47962380
Effects of an antithrombotic agent (MD-805) on progressing cerebral thrombosis.Q54049123
Mediation of reocclusion by thromboxane A2 and serotonin after thrombolysis with tissue-type plasminogen activator in a canine preparation of coronary thrombosis.Q54127127
Paired analysis of urinary thromboxane B2 metabolites in humans.Q54367265
Marked platelet activation in vivo after intravenous streptokinase in patients with acute myocardial infarctionQ68123206
A randomized controlled trial of intravenous tissue plasminogen activator and early intravenous heparin in acute myocardial infarctionQ69175486
Paradoxic elevation of fibrinopeptide A after streptokinase: evidence for continued thrombosis despite intense fibrinolysisQ69224498
Activation/inactivation of human factor V by plasminQ69292314
Role of heparin after intravenous thrombolytic therapy for acute myocardial infarctionQ69740665
Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human plateletsQ69871824
Effect of a selective thrombin inhibitor MCI-9038 on fibrinolysis in vitro and in vivoQ69889541
The role of activated human platelets in prothrombin and factor X activationQ70048529
Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation?Q70265367
An enzyme linked immunosorbent assay for determination of tissue plasminogen activator applied to patients with thromboembolic diseaseQ70304959
Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GPIIb/IIIa antibody in a canine preparationQ70376888
Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolitesQ70875398
Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl++ +) sulfonyl]-l-arginyl)]-2-piperidinecarboxylic acidQ71255368
Electrical induction of coronary artery thrombosis in the ambulatory canine: a model for in vivo evaluation of anti-thrombotic agentsQ71281988
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectthrombolysisQ1931577
plasminogenQ107129060
P304page(s)7585-7589
P577publication date1989-10-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleRole of thrombin and thromboxane A2 in reocclusion following coronary thrombolysis with tissue-type plasminogen activator
P478volume86

Reverse relations

cites work (P2860)
Q40342837Acceleration of the thrombin inactivation of single chain urokinase-type plasminogen activator (pro-urokinase) by thrombomodulin
Q73364963Adjunctive Therapy with an Antithrombotic Drug Can Prevent Reocclusion and Induce Residual Thrombus Reduction After Percutaneous Transcatheter Angioplasty of the Thrombotic Lesions
Q36864128Adjuvant effect of argatroban on staphylokinase induced thrombolysis of platelet rich thrombi in rat mesenteric venules in vivo
Q40432300Antiplatelet drugs. A comparative review
Q33606832Antiplatelet therapy--Part I
Q41865617Antithrombotic actions of the thrombin inhibitor, argatroban, in a canine model of coronary cyclic flow: comparison with heparin
Q41834459Antithrombotic effect of a novel recombinant hirudin analogue, CX-397, in a rat arterial thrombosis model
Q42548747Antithrombotic effects in a rat model of aspirin-insensitive arterial thrombosis of desethyl KBT-3022, the main active metabolite of a new antiplatelet agent, KBT-3022.
Q52314493Argatroban During Percutaneous Transluminal Coronary Angioplasty: Results of a Dose-Verification Study.
Q73448113Argatroban, a thrombin inhibitor, decreased mortality after 10 min of forebrain ischemia in the gerbil
Q24561385Characterization of a functional thrombin receptor. Issues and opportunities
Q34126365Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents.
Q35796005Critical review of mouse models of venous thrombosis
Q73295856Effect of Thrombin Inhibition on Patients with Peripheral Arterial Obstructive Disease: A Multicenter Clinical Trial of Argatroban
Q42717484Effects of vapiprost, a novel thromboxane receptor antagonist, on thrombus formation and vascular patency after thrombolysis by tissue-type plasminogen activator
Q71974401Endogenous and Exogenous Nitric Oxide Protect Against Intracoronary Thrombosis and Reocclusion After Thrombolysis
Q30843513Enhanced endogenous thrombolysis induced by a specific factor Xa inhibitor, DX-9065a, evaluated in a rat arterial thrombolysis model in vivo.
Q41082452Fibrinolytic mechanism, biochemistry, and preclinical pharmacology of recombinant prourokinase
Q67870384Heparin and the thrombin inhibitor argatroban enhance fibrinolysis by infused or bolus-injected saruplase (r-scu-PA) in rabbit femoral artery thrombosis
Q34536091Historical lessons in translational medicine: cyclooxygenase inhibition and P2Y12 antagonism
Q73302807In vitro antiplatelet profile of FR171113, a novel non-peptide thrombin receptor antagonist
Q73128626Inhibition of arterial thrombosis by a peptide ligand of the thrombin receptor
Q35805471Light-activated protein inhibition through photoinduced electron transfer of a ruthenium(II)-cobalt(III) bimetallic complex
Q47339841Local treatment with an antithrombotic drug reduces thrombus size in coronary and peripheral thrombosed arteries
Q30305538Management of Acute Ischemic Coronary Syndromes: The Present and Future
Q39329081Modeling thrombus formation and growth
Q40463597Novel Antithrombotic Drugs in Development
Q71129084Pathophysiology of coronary artery disease
Q40559317Pharmacology of current and future antithrombotic therapies.
Q37806238Platelets and fibrinolysis
Q45058323Prediction of Thrombus Growth: Effect of Stenosis and Reynolds Number
Q39048394Proinflammatory signaling functions of thrombin in cancer.
Q71974513Role of Thrombin Compared With Factor Xa in the Procoagulant Activity of Whole Blood Clots
Q47360550Search for an animal model to investigate selective pulmonary vasodilation
Q73755199Shifts in the affinity distribution of one class of seven-transmembrane receptors by activation of a separate class of seven-transmembrane receptors
Q40664734Specific thrombin inhibitors in vivo
Q34208881Systemic lysis protects against the effects of platelet activation during coronary thrombolysis
Q41614451Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function
Q32043322The antithrombotic effect of potent bifunctional thrombin inhibitors based on hirudin sequence, P551 and P532, on He-Ne laser-induced thrombosis in rat mesenteric microvessels
Q41734671The isoprostanes: a perspective
Q33392640Therapeutic Implications of a Specific Murine Monoclonal Antibody (7E3) to the Platelet Receptor GPIIb/IIIa
Q40486965Thrombin and antithrombotic therapy in interventional cardiology
Q35607594Thrombin receptor expression in normal and atherosclerotic human arteries
Q37113049Thromboxane A2 receptor antagonists