A novel latent membrane 2 transcript expressed in Epstein-Barr virus-positive NK- and T-cell lymphoproliferative disease encodes a target for cellular immunotherapy

scientific article published on 29 July 2010

A novel latent membrane 2 transcript expressed in Epstein-Barr virus-positive NK- and T-cell lymphoproliferative disease encodes a target for cellular immunotherapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2010-06-292268
P932PMC publication ID2981530
P698PubMed publication ID20671118
P5875ResearchGate publication ID45423850

P50authorAndrew I BellQ37376473
Martin RoweQ37376494
Christopher P FoxQ57040255
Wing C ChanQ87934470
Catherine M BollardQ91774704
Claire Shannon LoweQ95607355
P2093author name stringAlan B Rickinson
Heather M Long
Steven P Lee
Javeed Iqbal
Graham S Taylor
Simon O'Connor
Tracey A Haigh
P2860cites workThe generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin diseaseQ31088065
Clinical differences between nasal and extranasal natural killer/T-cell lymphoma: a study of 136 cases from the International Peripheral T-Cell Lymphoma ProjectQ33382121
The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradationQ33396983
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipientsQ33634455
Clinical and virologic characteristics of chronic active Epstein-Barr virus infectionQ34082763
The Epstein-Barr virus nuclear antigen 2 interacts with an EBNA2 responsive cis-element of the terminal protein 1 gene promoterQ34355226
Epstein-barr virus latent membrane protein 2B (LMP2B) modulates LMP2A activityQ35634286
The Epstein-Barr virus 3.5-kilobase latent membrane protein 1 mRNA initiates from a TATA-Less promoter within the first terminal repeatQ35842451
Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transductionQ35868359
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transferQ36059593
A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genomeQ36344649
Two related Epstein-Barr virus membrane proteins are encoded by separate genesQ36780955
Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2.Q39700355
Cyclical expression of EBV latent membrane protein 1 in EBV-transformed B cells underpins heterogeneity of epitope presentation and CD8+ T cell recognitionQ39886068
Epstein-Barr virus nuclear antigen 1-specific CD4+ T cells directly kill Epstein-Barr virus-carrying natural killer and T cellsQ39946166
Induction of EBV-latent membrane protein 1-specific MHC class II-restricted T-cell responses against natural killer lymphoma cellsQ40017285
EBV latent membrane proteins (LMPs) 1 and 2 as immunotherapeutic targets: LMP-specific CD4+ cytotoxic T cell recognition of EBV-transformed B cell lines.Q40022307
Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytesQ40048949
Concomitant increase of LMP1 and CD25 (IL-2-receptor alpha) expression induced by IL-10 in the EBV-positive NK lines SNK6 and KAI3.Q40225147
Epstein-Barr virus (EBV) latent membrane protein-1-specific cytotoxic T lymphocytes targeting EBV-carrying natural killer cell malignancies.Q40316208
Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignanciesQ40623874
Characterization of novel natural killer (NK)-cell and gammadelta T-cell lines established from primary lesions of nasal T/NK-cell lymphomas associated with the Epstein-Barr virusQ40831332
Monoclonal antibodies to the latent membrane protein of Epstein-Barr virus reveal heterogeneity of the protein and inducible expression in virus-transformed cellsQ42010316
Retroviral vectors for high-level transgene expression in T lymphocytesQ42798318
Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysisQ42802250
Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies.Q42810702
Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative diseaseQ43936463
The terminal protein gene 2 of Epstein-Barr virus is transcribed from a bidirectional latent promoter regionQ44081032
Quantitative analysis of Epstein-Barr virus (EBV)-related gene expression in patients with chronic active EBV infection.Q44657197
Excellent outcome of allogeneic hematopoietic SCT with reduced-intensity conditioning for the treatment of chronic active EBV infectionQ44766035
Analysis of Epstein-Barr virus latent gene expression in endemic Burkitt's lymphoma and nasopharyngeal carcinoma tumour cells by using quantitative real-time PCR assaysQ45412384
Expression of the Epstein-Barr virus (EBV)-encoded latent membrane protein 2A (LMP2A) in EBV-associated nasopharyngeal carcinomaQ45640598
Common cytological and cytogenetic features of Epstein-Barr virus (EBV)-positive natural killer (NK) cells and cell lines derived from patients with nasal T/NK-cell lymphomas, chronic active EBV infection and hydroa vacciniforme-like eruptionsQ45723253
Differential cellular targets of Epstein-Barr virus (EBV) infection between acute EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infectionQ45735795
Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients.Q45754081
Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the treatment of patients with EBV-positive relapsed Hodgkin's diseaseQ45756934
Immunohistochemical detection of the Epstein-Barr virus-encoded latent membrane protein 2A in Hodgkin's disease and infectious mononucleosisQ45760941
Nasal NK- and T-cell lymphomas share the same type of Epstein-Barr virus latency as nasopharyngeal carcinoma and Hodgkin's diseaseQ45766630
Sequence polymorphism in the Epstein-Barr virus latent membrane protein (LMP)-2 gene.Q45784236
Restoration of endogenous antigen processing in Burkitt's lymphoma cells by Epstein-Barr virus latent membrane protein-1: coordinate up-regulation of peptide transporters and HLA-class I antigen expressionQ45785307
Presence of Epstein-Barr virus DNA in nasal lymphomas of B and 'T' cell typeQ45853463
Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's diseaseQ60632741
A monoclonal antibody to the HLA-DR product recognizes a polymorphic Ia determinant in miceQ72638934
Conserved CTL epitopes within EBV latent membrane protein 2: a potential target for CTL-based tumor therapyQ73271294
Therapeutic outcome of extranodal NK/T-cell lymphoma initially treated with chemotherapy--result of chemotherapy in NK/T-cell lymphomaQ75200328
Radiotherapy as primary treatment for stage IE and IIE nasal natural killer/T-cell lymphomaQ82107025
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectimmunotherapyQ1427096
Epstein–Barr virusQ6900
P304page(s)3695-3704
P577publication date2010-07-29
P1433published inBloodQ885070
P1476titleA novel latent membrane 2 transcript expressed in Epstein-Barr virus-positive NK- and T-cell lymphoproliferative disease encodes a target for cellular immunotherapy
P478volume116

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cites work (P2860)
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