ALCAM regulates motility, invasiveness, and adherens junction formation in uveal melanoma cells.

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ALCAM regulates motility, invasiveness, and adherens junction formation in uveal melanoma cells. is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...739330J
P356DOI10.1371/JOURNAL.PONE.0039330
P932PMC publication ID3383762
P698PubMed publication ID22745734
P5875ResearchGate publication ID228089563

P50authorJoshua A. WeinerQ41445373
P2093author name stringChristopher S Stipp
Karry M Jannie
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
MEMD, a new cell adhesion molecule in metastasizing human melanoma cell lines, is identical to ALCAM (activated leukocyte cell adhesion molecule)Q24678256
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junctionQ24678766
Activated leukocyte cell adhesion molecule in breast cancer: prognostic indicatorQ24806155
Biochemical and Structural Definition of the l-Afadin- and Actin-binding Sites of alpha -CateninQ27638447
Coordinate recruitment of E-cadherin and ALCAM to cell-cell contacts by alpha-cateninQ28144710
Molecular basis for the homophilic activated leukocyte cell adhesion molecule (ALCAM)-ALCAM interactionQ28212934
ALCAM/CD166 is up-regulated in low-grade prostate cancer and progressively lost in high-grade lesionsQ28217430
Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasisQ28261479
MEMD/ALCAM: a potential marker for tumor invasion and nodal metastasis in esophageal squamous cell carcinomaQ28262234
Activated leukocyte cell adhesion molecule (ALCAM/CD166/MEMD), a novel actor in invasive growth, controls matrix metalloproteinase activityQ28275446
HCA, an immunoglobulin-like adhesion molecule present on the earliest human hematopoietic precursor cells, is also expressed by stromal cells in blood-forming tissuesQ28295406
Two cell adhesion molecules, nectin and cadherin, interact through their cytoplasmic domain-associated proteinsQ28511190
Axon fasciculation defects and retinal dysplasias in mice lacking the immunoglobulin superfamily adhesion molecule BEN/ALCAM/SC1Q28588934
Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interactionQ28592530
Dynamic regulation of activated leukocyte cell adhesion molecule-mediated homotypic cell adhesion through the actin cytoskeletonQ30477536
Mesenchymal stem cell surface antigen SB-10 corresponds to activated leukocyte cell adhesion molecule and is involved in osteogenic differentiationQ32066783
Role of cadherins in the transendothelial migration of melanoma cells in cultureQ32162592
Activated Leukocyte Cell Adhesion Molecule (ALCAM) is associated with suppression of breast cancer cells invasion.Q33248429
Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicryQ33874221
Molecular determinants of human uveal melanoma invasion and metastasis.Q52833056
Expression profiling of microdissected matched prostate cancer samples reveals CD166/MEMD and CD24 as new prognostic markers for patient survival.Q52941765
Activated leukocyte cell adhesion molecule expression is up-regulated in the development of endometrioid carcinoma.Q54381586
Expression of the cell to cell adhesion molecule, ALCAM, in breast cancer patients and the potential link with skeletal metastasis.Q54550537
Spatiotemporal pattern of retinal ganglion cell differentiation revealed by the expression of neurolin in embryonic zebrafishQ71369128
Uveal MelanomaQ73667094
N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cellsQ73812967
Function of Neurolin (DM-GRASP/SC-1) in guidance of motor axons during zebrafish developmentQ74040083
Cadherin switching in human prostate cancer progressionQ74052398
N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signallingQ74122026
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinomaQ74226097
Matrix metalloproteinases, their tissue inhibitors and colorectal cancer stagingQ74260950
Identification and characterization of a cell surface marker for embryonic rat spinal accessory motor neuronsQ74610220
Secondary motoneuron axons localize DM-GRASP on their fasciculated segmentsQ74671195
A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptorQ78423901
Low activated leukocyte cell adhesion molecule expression is associated with advanced tumor stage and early prostate-specific antigen relapse in prostate cancerQ84387605
Dynamics of intercellular communication during melanoma developmentQ33877030
Involvement of members of the cadherin superfamily in cancerQ33899441
The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism.Q34344754
Involvement of CD166 in the activation of human gamma delta T cells by tumor cells sensitized with nonpeptide antigensQ34544377
Proteomic identification of desmoglein 2 and activated leukocyte cell adhesion molecule as substrates of ADAM17 and ADAM10 by difference gel electrophoresisQ34718289
New insights into the diversity and function of neuronal immunoglobulin superfamily moleculesQ35071009
Biology and pathology of nectins and nectin-like moleculesQ35885625
Development and pathology of the hyaloid, choroidal and retinal vasculature.Q35959824
N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expressionQ36294742
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasisQ36316373
Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migrationQ36692831
Authenticating cell lines in ophthalmic research laboratoriesQ36957655
Activated leukocyte cell adhesion molecule: a new paradox in cancerQ37086373
Cadherins in development and cancerQ37218718
Cadherins and cancer: how does cadherin dysfunction promote tumor progression?Q37333596
The immunoglobulin superfamily of neuronal cell adhesion molecules: lessons from animal models and correlation with human disease.Q37346309
Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleuraQ38308730
ALCAM regulates mediolateral retinotopic mapping in the superior colliculus.Q39762329
The ALCAM shedding by the metalloprotease ADAM17/TACE is involved in motility of ovarian carcinoma cellsQ40028830
Regulation of the assembly and adhesion activity of E-cadherin by nectin and afadin for the formation of adherens junctions in Madin-Darby canine kidney cellsQ40338912
P-cadherin promotes cell-cell adhesion and counteracts invasion in human melanomaQ40365844
Separation force measurements reveal different types of modulation of E-cadherin-based adhesion by nectin-1 and -3.Q40490358
ALCAM (CD166): its role in hematopoietic and endothelial development.Q40778909
CD6 recognizes the neural adhesion molecule BEN.Q41849984
ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survivalQ41983868
Filamin A is a phosphorylation target of membrane but not cytosolic adenylyl cyclase activityQ42017189
Activated leukocyte cell adhesion molecule/CD166, a marker of tumor progression in primary malignant melanoma of the skinQ42026021
Role of cell adhesion molecule DM-GRASP in growth and orientation of retinal ganglion cell axonsQ42463886
Cell adhesion molecule SC1/DMGRASP is expressed on growing axons of retina ganglion cells and is involved in mediating their extension on axonsQ42492905
Expression of type VI collagen in uveal melanoma: its role in pattern formation and tumor progression.Q42811750
MuSC, a novel member of the immunoglobulin superfamily, is expressed in neurons of a subset of cranial sensory ganglia in the mouse embryoQ42819046
Heterogeneity of barrier function in the lung reflects diversity in endothelial cell junctionsQ43124033
Molecular genetic profiling of Gleason grade 4/5 prostate cancers compared to benign prostatic hyperplasiaQ46123919
Zebrafish neurolin-a and -b, orthologs of ALCAM, are involved in retinal ganglion cell differentiation and retinal axon pathfindingQ46183824
Frontline: Optimal T cell activation requires the engagement of CD6 and CD166.Q47867827
Molecular characterization of fish neurolin: a growth-associated cell surface protein and member of the immunoglobulin superfamily in the fish retinotectal system with similarities to chick protein DM-GRASP/SC-1/BEN.Q48083764
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectuveal melanomaQ356372
neoplastic invasivenessQ112498967
P304page(s)e39330
P577publication date2012-06-26
P1433published inPLOS OneQ564954
P1476titleALCAM regulates motility, invasiveness, and adherens junction formation in uveal melanoma cells
P478volume7

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cites work (P2860)
Q38693867A Combination of Species Identification and STR Profiling Identifies Cross-contaminated Cells from 482 Human Tumor Cell Lines
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