scholarly article | Q13442814 |
P2093 | author name string | Jiyong Zhao | |
David Oleksyn | |||
Elise Van Pelt | |||
Ignacio Sanz | |||
Joel Shapiro | |||
Luojing Chen | |||
Mary Pulvino | |||
Michael DeRan | |||
Yue Liang | |||
P2860 | cites work | Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation | Q24321363 |
Direct activation of protein kinases by unanchored polyubiquitin chains | Q24324679 | ||
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma | Q24613755 | ||
The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation | Q27687790 | ||
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling | Q27860529 | ||
Regulation and function of IKK and IKK-related kinases | Q28268930 | ||
Aggressive lymphomas | Q28279743 | ||
E2s: structurally economical and functionally replete | Q28301074 | ||
Oncogenically active MYD88 mutations in human lymphoma | Q28301648 | ||
Protein-protein interaction antagonists as novel inhibitors of non-canonical polyubiquitylation | Q28474754 | ||
PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling | Q28509628 | ||
Shared principles in NF-kappaB signaling | Q29547234 | ||
Function and activation of NF-kappa B in the immune system | Q29547790 | ||
Building ubiquitin chains: E2 enzymes at work | Q29619578 | ||
Inflammation meets cancer, with NF-κB as the matchmaker | Q29620242 | ||
The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma | Q33523956 | ||
Chemical biology strategy reveals pathway-selective inhibitor of NF-kappaB activation induced by protein kinase C | Q33530203 | ||
Signaling to NF-kappaB: regulation by ubiquitination | Q33693806 | ||
Oncogenic activation of NF-kappaB. | Q33849388 | ||
Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1. | Q33862991 | ||
Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1. | Q34080225 | ||
Analysis of the coding genome of diffuse large B-cell lymphoma | Q34205133 | ||
TR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors. | Q34232394 | ||
Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma. | Q34277639 | ||
The biology of human lymphoid malignancies revealed by gene expression profiling. | Q34313320 | ||
p53 Research: the past thirty years and the next thirty years. | Q34313764 | ||
Ubiquitin in motion: structural studies of the ubiquitin-conjugating enzyme∼ubiquitin conjugate | Q34666396 | ||
Novel therapeutics for aggressive non-Hodgkin's lymphoma | Q35111768 | ||
Regulation of p53 localization and activity by Ubc13. | Q35131633 | ||
Control of lymphocyte development by nuclear factor-kappaB. | Q36133144 | ||
Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells | Q36369816 | ||
Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition | Q36421122 | ||
Assessing G1-to-S-phase progression after genotoxic stress | Q36819856 | ||
Regulatory ubiquitylation in response to DNA double-strand breaks | Q37397281 | ||
NF-kappaB as a critical link between inflammation and cancer | Q37412699 | ||
Regulation of hematopoiesis by the K63-specific ubiquitin-conjugating enzyme Ubc13. | Q37469728 | ||
B cells as therapeutic targets in SLE. | Q37603296 | ||
Targeted treatment and new agents in diffuse large B cell lymphoma | Q37766121 | ||
Expanding role of ubiquitination in NF-κB signaling | Q37816941 | ||
Malignant pirates of the immune system | Q37936211 | ||
TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas | Q38352213 | ||
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma | Q40005246 | ||
Protein kinase C-associated kinase is required for NF-kappaB signaling and survival in diffuse large B-cell lymphoma cells | Q40048470 | ||
Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics. | Q40073550 | ||
Structural and functional characterization of the promoter regions of the NFKB2 gene | Q40394584 | ||
Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. | Q40465454 | ||
Alterations of the p53 tumor suppressor gene in diffuse large cell lymphomas with translocations of the c-MYC and BCL-2 proto-oncogenes | Q41497109 | ||
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling | Q56897808 | ||
Leucettamol A: A new inhibitor of Ubc13-Uev1A interaction isolated from a marine sponge, Leucetta aff. microrhaphis | Q59710699 | ||
Cutting Edge: Pivotal function of Ubc13 in thymocyte TCR signaling | Q79370170 | ||
Diffuse large B-cell lymphoma | Q79711344 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | diffuse large B-cell lymphoma | Q2626074 |
B-cell lymphoma | Q4833719 | ||
P304 | page(s) | 1668-1677 | |
P577 | publication date | 2012-07-12 | |
P1433 | published in | Blood | Q885070 |
P1476 | title | Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A. | |
P478 | volume | 120 |
Q38805774 | A Generic Platform for Cellular Screening Against Ubiquitin Ligases |
Q37620709 | A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways |
Q64112676 | Blockade of HMGB1 signaling pathway by ethyl pyruvate inhibits tumor growth in diffuse large B-cell lymphoma |
Q35864085 | Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting |
Q26991974 | Deconstructing innate immune signaling in myelodysplastic syndromes |
Q50316561 | Delineating Crosstalk Mechanisms of the Ubiquitin Proteasome System That Regulate Apoptosis |
Q88879027 | Deregulation of autophagy under hyperglycemic conditions is dependent on increased lysine 63 ubiquitination: a candidate mechanism in the progression of diabetic nephropathy |
Q26752823 | Drugging the undruggables: exploring the ubiquitin system for drug development |
Q58694254 | Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes |
Q36158657 | E2 superfamily of ubiquitin-conjugating enzymes: constitutively active or activated through phosphorylation in the catalytic cleft |
Q92240507 | Emerging drug development technologies targeting ubiquitination for cancer therapeutics |
Q38530638 | Emerging roles of Lys63-linked polyubiquitylation in immune responses |
Q36020841 | Inhibition of COP9-signalosome (CSN) deneddylating activity and tumor growth of diffuse large B-cell lymphomas by doxycycline |
Q43892008 | Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development. |
Q33714747 | MLN4924, an NAE inhibitor, suppresses AKT and mTOR signaling via upregulation of REDD1 in human myeloma cells |
Q48213244 | MMP-25 Metalloprotease Regulates Innate Immune Response through NF-κB Signaling. |
Q46330068 | MicroRNAs as predictors for CNS relapse of systemic diffuse large B-cell lymphoma |
Q51049413 | Mitochondrial Retrograde Signaling in Mammals Is Mediated by the Transcriptional Cofactor GPS2 via Direct Mitochondria-to-Nucleus Translocation |
Q52644438 | New Insights into the Role of E2s in the Pathogenesis of Diseases: Lessons Learned from UBE2O. |
Q36189276 | Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling |
Q58601460 | Oncogenic mutations in IKKβ function through global changes induced by K63-linked ubiquitination and result in autocrine stimulation |
Q50678340 | PKK deficiency in B cells prevents lupus development in Sle lupus mice. |
Q60934720 | Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88 |
Q34722684 | Protein ubiquitination in lymphoid malignancies |
Q52936872 | Proteomics analysis of malignant and benign prostate tissue by 2D DIGE/MS reveals new insights into proteins involved in prostate cancer. |
Q38252591 | Screening for E3-ubiquitin ligase inhibitors: challenges and opportunities |
Q35232335 | Screening of DUB activity and specificity by MALDI-TOF mass spectrometry |
Q89623181 | Strategies to Target ISG15 and USP18 Toward Therapeutic Applications |
Q37282157 | Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks |
Q64077112 | Suppression of the Ubiquitin Pathway by Small Molecule Binding to Ubiquitin Enhances Doxorubicin Sensitivity of the Cancer Cells |
Q89295152 | Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity |
Q87038902 | Targeting the ubiquitin-proteasome system for cancer therapy |
Q36936317 | The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system |
Q63976983 | Triggering MSR1 promotes JNK‐mediated inflammation in IL‐4‐activated macrophages |
Q26739716 | Ubc13: the Lys63 ubiquitin chain building machine |
Q89814914 | Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination |
Q90285535 | Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy |
Q34468776 | Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation. |
Q98946924 | Ubiquitination status does not affect Vps34 degradation |
Q91893608 | Uev1A promotes breast cancer cell survival and chemoresistance through the AKT-FOXO1-BIM pathway |
Q55260947 | Uev1A-Ubc13 promotes colorectal cancer metastasis through regulating CXCL1 expression via NF-кB activation. |
Q26827754 | When ubiquitin meets NF-κB: a trove for anti-cancer drug development |
Q38699817 | XIAP upregulates expression of HIF target genes by targeting HIF1α for Lys63-linked polyubiquitination |
Search more.