Negative feedback defining a circadian clock: autoregulation of the clock gene frequency

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Negative feedback defining a circadian clock: autoregulation of the clock gene frequency is …
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scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.8128244
P698PubMed publication ID8128244
P5875ResearchGate publication ID15071497

P2093author name stringDunlap JC
Loros JJ
Johnson KA
Aronson BD
P433issue5153
P407language of work or nameEnglishQ1860
P921main subjectcatabolic 3-dehydroquinaseQ63034307
period clock protein FRQQ63035159
period clock protein FRQ, variant 2Q63035175
period clock protein FRQ, variant 1Q63035187
circadian rhythmQ208353
P304page(s)1578-1584
P577publication date1994-03-01
P1433published inScienceQ192864
P1476titleNegative feedback defining a circadian clock: autoregulation of the clock gene frequency
P478volume263

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cites work (P2860)
Q39646314A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa
Q34784363A circadian clock in Neurospora: how genes and proteins cooperate to produce a sustained, entrainable, and compensated biological oscillator with a period of about a day
Q34338187A circadian clock nanomachine that runs without transcription or translation
Q24646091A circadian enhancer mediates PER-dependent mRNA cycling in Drosophila melanogaster
Q34482897A circadian oscillator in the fungus Botrytis cinerea regulates virulence when infecting Arabidopsis thaliana.
Q30480898A developmental cycle masks output from the circadian oscillator under conditions of choline deficiency in Neurospora
Q35857032A double-stranded-RNA response program important for RNA interference efficiency
Q34644548A genetic selection for circadian output pathway mutations in Neurospora crassa
Q40486745A locus for circadian period of locomotor activity on mouse proximal chromosome 3.
Q52228630A mathematical model for the intracellular circadian rhythm generator.
Q40868342A model for circadian rhythms in Drosophila incorporating the formation of a complex between the PER and TIM proteins
Q34189667A model for the Neurospora circadian clock
Q48133127A model of molecular circadian clocks: multiple mechanisms for phase shifting and a requirement for strong nonlinear interactions.
Q47069990A molecular rhythm mediating circadian clock output in Drosophila
Q33886957A new gene encoding a putative transcription factor regulated by the Drosophila circadian clock
Q34332338A nitrate-induced frq-less oscillator in Neurospora crassa
Q35847102A novel circadianly expressed Drosophila melanogaster gene dependent on the period gene for its rhythmic expression
Q64107911A period without PER: understanding 24-hour rhythms without classic transcription and translation feedback loops
Q34103095A phosphate-regulated promoter for fine-tuned and reversible overexpression in Ostreococcus: application to circadian clock functional analysis
Q39778327A reporter for dsRNA response in Neurospora crassa
Q34106042All in good time: the Arabidopsis circadian clock
Q34506769Alternative Use of DNA Binding Domains by the Neurospora White Collar Complex Dictates Circadian Regulation and Light Responses
Q34426042Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY.
Q36490210An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC.
Q34488761Analysis of Circadian Rhythms in the Basal Filamentous Ascomycete Pyronema confluens.
Q50304405Analysis of circadian rhythms in Neurospora: overview of assays and genetic and molecular biological manipulation
Q46427453Analysis of posttranslational regulations in the Neurospora circadian clock
Q37461459Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing
Q40465967Are competing intermolecular and intramolecular interactions of PERIOD protein important for the regulation of circadian rhythms in Drosophila?
Q33865588Assignment of circadian function for the Neurospora clock gene frequency
Q36544866AtGRP7, a nuclear RNA-binding protein as a component of a circadian-regulated negative feedback loop in Arabidopsis thaliana
Q40877119Autoregulation of ZEB2 expression for zearalenone production in Fusarium graminearum.
Q43024822Biochemistry that times the day.
Q55052718Biological Oscillators in Nanonetworks-Opportunities and Challenges.
Q37252451CATP is a critical component of the Neurospora circadian clock by regulating the nucleosome occupancy rhythm at the frequency locus
Q33979542CHD1 remodels chromatin and influences transient DNA methylation at the clock gene frequency.
Q35052569CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop
Q34482717CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity
Q33671788CaMKII is essential for the cellular clock and coupling between morning and evening behavioral rhythms
Q33641545Cellular circadian clocks in the pineal
Q38866276Circadian Rhythms and Sleep in Drosophila melanogaster.
Q47989012Circadian and light-induced expression of luciferase in Neurospora crassa
Q38962639Circadian and seasonal variation of the body temperature of sheep in a tropical environment
Q41610173Circadian and ultradian clock-controlled rhythms in unicellular microorganisms
Q34331733Circadian clock locus frequency: protein encoded by a single open reading frame defines period length and temperature compensation
Q42063432Circadian clock neurons in the silkmoth Antheraea pernyi: novel mechanisms of Period protein regulation
Q36688004Circadian clock-controlled genes isolated from Neurospora crassa are late night- to early morning-specific
Q33908192Circadian clock-protein expression in cyanobacteria: rhythms and phase setting.
Q33941045Circadian clock-specific roles for the light response protein WHITE COLLAR-2.
Q35785849Circadian clocks and natural antisense RNA.
Q34770773Circadian entrainment of Neurospora crassa
Q38615111Circadian mRNA expression: insights from modeling and transcriptomics
Q34770746Circadian output, input, and intracellular oscillators: insights into the circadian systems of single cells
Q48617126Circadian phase shifts to neuropeptide Y In vitro: cellular communication and signal transduction.
Q33781149Circadian regulation of a Drosophila homolog of the mammalian Clock gene: PER and TIM function as positive regulators
Q39673509Circadian regulation of the light input pathway in Neurospora crassa
Q41346896Circadian rhythms and autoregulatory transcription loops--going round in circles?
Q52551813Circadian rhythms and protein turnover: the effect of temperature on the period lengths of clock mutants simulated by the Goodwin oscillator.
Q28751778Circadian rhythms from multiple oscillators: lessons from diverse organisms
Q34555404Circadian rhythms in Neurospora crassa and other filamentous fungi
Q30496478Circadian rhythms in Neurospora crassa: dynamics of the clock component frequency visualized using a fluorescent reporter
Q34224497Circadian rhythms in Neurospora crassa: farnesol or geraniol allow expression of rhythmicity in the otherwise arrhythmic strains frq10, wc-1, and wc-2.
Q37149404Circadian rhythms in Neurospora crassa: lipid deficiencies restore robust rhythmicity to null frequency and white-collar mutants.
Q41745724Circadian rhythms in Neurospora: a new measurement, the reset zone
Q47161365Circadian rhythms in parasites
Q37543986Circadian rhythms synchronize mitosis in Neurospora crassa
Q34460462Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination
Q48964546Circadian rhythms. Ion channels get the message
Q52551793Circadian rhythms. Same clock, different works.
Q52541672Circadian rhythms. What makes the clock tick?
Q48364199Circadian rhythms: molecular basis of the clock
Q33822176Circadian systems and metabolism
Q34441294Circadian systems: different levels of complexity
Q36249981Circadian timekeeping: loops and layers of transcriptional control
Q35943707Circadian timing mechanism in the prokaryotic clock system of cyanobacteria
Q47955502Circadian-regulated expression of a nuclear-encoded plastid sigma factor gene (sigA) in wheat seedlings
Q33913632Circuit topology and the evolution of robustness in two-gene circadian oscillators
Q35943696Clock genes, oscillators, and cellular networks in the suprachiasmatic nuclei
Q36995404Closing the circadian negative feedback loop: FRQ-dependent clearance of WC-1 from the nucleus
Q52726147Codon usage biases co-evolve with transcription termination machinery to suppress premature cleavage and polyadenylation.
Q37346918Codon usage is an important determinant of gene expression levels largely through its effects on transcription.
Q33935899Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora
Q35198806Combining theoretical and experimental approaches to understand the circadian clock.
Q63035166Common threads in eukaryotic circadian systems
Q46662035Computational cell biology: past, present and future.
Q62965004Conidiation rhythm and light entrainment in superoxide dismutase mutant in Neurospora crassa
Q28264866Conserved regions of the timeless (tim) clock gene in Drosophila analyzed through phylogenetic and functional studies
Q46184417Constitutive expression of the CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) gene disrupts circadian rhythms and suppresses its own expression
Q37635108Constitutive overexpression of the Drosophila period protein inhibits period mRNA cycling
Q37028231Control of WHITE COLLAR localization by phosphorylation is a critical step in the circadian negative feedback process
Q46691191Coordination of Plant Metabolism and Development by the Circadian Clock
Q28478236Cross-talk between the cellular redox state and the circadian system in Neurospora
Q49996929Crosstalk between circadian rhythmicity, mitochondrial dynamics and macrophage bactericidal activity
Q35701642Cyanobacterial circadian clocks--timing is everything
Q36211553Cycling of CRYPTOCHROME proteins is not necessary for circadian-clock function in mammalian fibroblasts
Q33707409DCAF26, an Adaptor Protein of Cul4-Based E3, Is Essential for DNA Methylation in Neurospora crassa
Q50561900DNA Replication Is Required for Circadian Clock Function by Regulating Rhythmic Nucleosome Composition
Q46269455Daily rhythms and enrichment patterns in the transcriptome of the behavior-manipulating parasite Ophiocordyceps kimflemingiae
Q41107521Daily rhythms in cells of the fly's optic lobe: taking time out from the circadian clock
Q51778571Dependence of the period on the rate of protein degradation in minimal models for circadian oscillations.
Q52539507Disruption of synaptic transmission or clock-gene-product oscillations in circadian pacemaker cells of Drosophila cause abnormal behavioral rhythms.
Q28081724Dissecting the mechanisms of the clock in Neurospora
Q36106744Dissection of a circadian oscillation into discrete domains
Q36557031Distinct cis-acting elements mediate clock, light, and developmental regulation of the Neurospora crassa eas (ccg-2) gene
Q36057291Distinct roles for PP1 and PP2A in the Neurospora circadian clock
Q33905183Distinct signaling pathways from the circadian clock participate in regulation of rhythmic conidiospore development in Neurospora crassa
Q64277096Drosophila CrebB is a Substrate of the Nonsense-Mediated mRNA Decay Pathway that Sustains Circadian Behaviors
Q36573093Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function
Q73224969Effect of 24 hours light on circadian rhythms of secretory enzymes and morphology of rat von Ebner's glands
Q33277980Enabling a community to dissect an organism: overview of the Neurospora functional genomics project
Q37519764Engineered temperature compensation in a synthetic genetic clock.
Q36474473Entrainment of the Neurospora circadian clock
Q73197651Environmental and genetic effects on circadian clock-regulated gene expression in Arabidopsis
Q26801305Epigenetic and Posttranslational Modifications in Light Signal Transduction and the Circadian Clock in Neurospora crassa
Q41863677Epistatic and synergistic interactions between circadian clock mutations in Neurospora crassa
Q30469735Evidence for a central role of transcription in the timing mechanism of a circadian clock
Q47070062Evidence that the TIM light response is relevant to light-induced phase shifts in Drosophila melanogaster
Q48264383Expression of basic helix-loop-helix/PAS genes in the mouse suprachiasmatic nucleus
Q46101003Extent and character of circadian gene expression in Drosophila melanogaster: identification of twenty oscillating mRNAs in the fly head
Q90287895FRQ-CK1 interaction determines the period of circadian rhythms in Neurospora
Q33688816FRQ-interacting RNA helicase mediates negative and positive feedback in the Neurospora circadian clock
Q34225555FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation
Q48791013Fifty years of fun.
Q35944728Finding new clock components: past and future.
Q33786067Forty years of PRCs--what have we learned?
Q37316585Forward and reverse genetic approaches to behavior in the mouse
Q35022467Functional conservation of light, oxygen, or voltage domains in light sensing
Q37150579Functional identification of the mouse circadian Clock gene by transgenic BAC rescue
Q33799798Functional significance of FRH in regulating the phosphorylation and stability of Neurospora circadian clock protein FRQ
Q37190992Fungal functional genomics: tunable knockout-knock-in expression and tagging strategies
Q57944140Fungi with a sense of time: molecular genetics of temporal organization in Neurospora crassa
Q34232866Genetic and molecular analysis of phytochromes from the filamentous fungus Neurospora crassa
Q33827352Genetic and molecular characterization of a cryptochrome from the filamentous fungus Neurospora crassa
Q35644651Genetic clock of biologic rhythms.
Q33772363Genetic interactions between clock mutations in Neurospora crassa: can they help us to understand complexity?
Q37196142Genome-wide analysis of light-inducible responses reveals hierarchical light signalling in Neurospora
Q34213465Genome-wide characterization of light-regulated genes in Neurospora crassa.
Q48040746Glyceraldehyde-3-phosphate dehydrogenase is regulated on a daily basis by the circadian clock
Q36474477How temperature affects the circadian clock of Neurospora crassa
Q48343720Identification of a calcium/calmodulin-dependent protein kinase that phosphorylates the Neurospora circadian clock protein FREQUENCY.
Q77331772Identification of tomato Lhc promoter regions necessary for circadian expression
Q47782407Increasing the Unneddylated Cullin1 Portion Rescues the csn Phenotypes by Stabilizing Adaptor Modules To Drive SCF Assembly
Q42456837Inhibitors of messenger RNA and protein synthesis affect differently serotonin arylalkylamine N-acetyltransferase activity in clock-controlled and non clock-controlled fish pineal
Q37632149Intergeneric complementation of a circadian rhythmicity defect: phylogenetic conservation of structure and function of the clock gene frequency
Q24629961Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock
Q30442083Interplay of circadian clocks and metabolic rhythms
Q26997834Intricate protein-protein interactions in the cyanobacterial circadian clock
Q21134535Intrinsic noise analyzer: a software package for the exploration of stochastic biochemical kinetics using the system size expansion
Q33970123Isolation and characterization of a temperature-sensitive circadian clock mutant of Neurospora crassa.
Q34389969KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria.
Q37415096Lessons from fungal F-box proteins
Q35684970Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism
Q52208901Light induction of the clock-controlled gene ccg-1 is not transduced through the circadian clock in Neurospora crassa.
Q39647708Light reception and circadian behavior in 'blind' and 'clock-less' mutants of Neurospora crassa
Q41074257Light, immediate-early genes, and circadian rhythms
Q50485868Light-independent phosphorylation of WHITE COLLAR-1 regulates its function in the Neurospora circadian negative feedback loop
Q34299022Light-induced resetting of a circadian clock is mediated by a rapid increase in frequency transcript
Q34452201Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript.
Q36297158Light-inducible system for tunable protein expression in Neurospora crassa
Q34718029Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms
Q34072051Lose and gain: impacts of ERK5 and JNK cascades on each other
Q48567871Luteinizing hormone-releasing hormone (LHRH) neurons maintained in hypothalamic slice explant cultures exhibit a rapid LHRH mRNA turnover rate.
Q50252008Making Time: Conservation of Biological Clocks from Fungi to Animals
Q39426866Mathematical modeling and validation of glucose compensation of the neurospora circadian clock
Q34442830Mechanism of the Neurospora circadian clock, a FREQUENCY-centric view
Q34408902Metabolic and nontranscriptional circadian clocks: eukaryotes
Q26859160Metabolic compensation and circadian resilience in prokaryotic cyanobacteria
Q36199012Methods to study molecular mechanisms of the Neurospora circadian clock
Q33879795Microbial circadian oscillatory systems in Neurospora and Synechococcus: models for cellular clocks.
Q41594599Modeling temperature compensation in chemical and biological oscillators
Q39569070Modulation of Circadian Gene Expression and Metabolic Compensation by the RCO-1 Corepressor of Neurospora crassa.
Q61563793Molecular Genetics of Circadian Rhythms in Neurospora Crassa
Q28297151Molecular bases for circadian clocks
Q34227065Molecular mechanism of light responses in Neurospora: from light-induced transcription to photoadaptation
Q35130978Molecular mechanism of suppression of circadian rhythms by a critical stimulus
Q37825823Molecular mechanism of the Neurospora circadian oscillator
Q35163390Molecular mechanisms of entrainment in the Neurospora circadian clock
Q37089665Multiple oscillators regulate circadian gene expression in Neurospora
Q104495376Multiple random phosphorylations in clock proteins provide long delays and switches
Q28252722Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior
Q42007943Mutants with altered sensitivity to a calmodulin antagonist affect the circadian clock in Neurospora crassa
Q33964737Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing.
Q36685802My Path from Chemistry to Phytochrome and Circadian Rhythms
Q46280250Natural Variation of the Circadian Clock in Neurospora.
Q28483644Neurospora COP9 signalosome integrity plays major roles for hyphal growth, conidial development, and circadian function
Q21144866Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle
Q33905410Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development
Q30427327Non-optimal codon usage affects expression, structure and function of clock protein FRQ
Q64998192Non-transcriptional processes in circadian rhythm generation.
Q30375176Nonoptimal codon usage influences protein structure in intrinsically disordered regions
Q90163040Opposite Nuclear Dynamics of Two FRH-Dominated Frequency Proteins Orchestrate Non-Rhythmic Conidiation in Beauveria bassiana
Q34440702PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses of Neurospora
Q81391270PSEUDO-RESPONSE REGULATOR 7 and 9 are partially redundant genes essential for the temperature responsiveness of the Arabidopsis circadian clock
Q58606720Periodicity, repression, and the molecular architecture of the mammalian circadian clock
Q24631336Peroxiredoxins are conserved markers of circadian rhythms
Q37362847Phosphorylation modulates rapid nucleocytoplasmic shuttling and cytoplasmic accumulation of Neurospora clock protein FRQ on a circadian time scale.
Q24684218Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock
Q24648053Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock
Q34338768Phosphorylation-dependent maturation of Neurospora circadian clock protein from a nuclear repressor toward a cytoplasmic activator
Q30471179Phototransduction and circadian clock pathways regulating gene transcription in higher plants
Q33890469Physical interactions among circadian clock proteins KaiA, KaiB and KaiC in cyanobacteria
Q34161788Population genomics and local adaptation in wild isolates of a model microbial eukaryote
Q28238809Positional cloning of the mouse circadian clock gene
Q33887839Post-transcriptional regulation contributes to Drosophila clock gene mRNA cycling
Q34605395Post-translational modifications regulate the ticking of the circadian clock.
Q37141000Posttranslational control of the Neurospora circadian clock
Q28652178Potential conservation of circadian clock proteins in the phylum Nematoda as revealed by bioinformatic searches
Q36103066Profile of Jay C. Dunlap
Q36209723Protein kinase A and casein kinases mediate sequential phosphorylation events in the circadian negative feedback loop
Q36564564Proteins in the Neurospora circadian clockworks
Q42119372QIP, a putative exonuclease, interacts with the Neurospora Argonaute protein and facilitates conversion of duplex siRNA into single strands
Q30470608Quantitative analysis of Drosophila period gene transcription in living animals
Q34441326RNA-binding proteins and circadian rhythms in Arabidopsis thaliana.
Q64940751Reflections on contributing to "big discoveries" about the fly clock: Our fortunate paths as post-docs with 2017 Nobel laureates Jeff Hall, Michael Rosbash, and Mike Young.
Q47071183Regulation of a specific circadian clock output pathway by lark, a putative RNA-binding protein with repressor activity
Q37168364Regulation of circadian clocks by redox homeostasis
Q30051192Regulation of the Drosophila protein timeless suggests a mechanism for resetting the circadian clock by light
Q24557449Regulation of the Neurospora circadian clock by an RNA helicase
Q28215067Regulation of the Neurospora circadian clock by casein kinase II
Q34719694Regulation of the activity and cellular localization of the circadian clock protein FRQ.
Q60075983Resetting the circadian cycle
Q37443844Reversible phosphorylation subserves robust circadian rhythms by creating a switch in inactivating the positive element.
Q28588540Rhythmic PER abundance defines a critical nodal point for negative feedback within the circadian clock mechanism
Q35022401Rhythmic binding of a WHITE COLLAR-containing complex to the frequency promoter is inhibited by FREQUENCY
Q24799420Rhythmic expression of Nocturnin mRNA in multiple tissues of the mouse
Q35974767Robustness and period sensitivity analysis of minimal models for biochemical oscillators
Q35626075Role for Protein Kinase A in the Neurospora Circadian Clock by Regulating White Collar-Independent frequency Transcription through Phosphorylation of RCM-1.
Q59095405Role for antisense RNA in regulating circadian clock function in Neurospora crassa
Q73387290Role of circadian activation of mitogen-activated protein kinase in chick pineal clock oscillation
Q33769567Role of individual subunits of the Neurospora crassa CSN complex in regulation of deneddylation and stability of cullin proteins
Q52586585Role of molecular oscillations in generating behavioral rhythms in Drosophila.
Q34737389Salad days in the rhythms trade
Q34086905Seasonality and photoperiodism in fungi
Q34131958Selection for narrow gate of emergence results in correlated sex-specific changes in life history of Drosophila melanogaster
Q50932740Semi-algebraic optimization of temperature compensation in a general switch-type negative feedback model of circadian clocks
Q37250049Setting the pace of the Neurospora circadian clock by multiple independent FRQ phosphorylation events
Q36402233Simulating dark expressions and interactions of frq and wc-1 in the Neurospora circadian clock.
Q31956639Spermidine determines the sensitivity to the calmodulin antagonist, chlorpromazine, for the circadian conidiation rhythm but not for the mycelial growth in Neurospora crassa
Q35398714Stability depends on positive autoregulation in Boolean gene regulatory networks
Q37621646Suppression of PERIOD protein abundance and circadian cycling by the Drosophila clock mutation timeless
Q37395084Suppression of WC-independent frequency transcription by RCO-1 is essential for Neurospora circadian clock
Q34519322Suppression of WHITE COLLAR-independent frequency Transcription by Histone H3 Lysine 36 Methyltransferase SET-2 Is Necessary for Clock Function in Neurospora
Q73805200Surface plasmon resonance spectroscopy (SPR) interaction studies of the circadian-controlled tomato LHCa4*1 (CAB 11) protein with its promoter
Q37264088Synchronous activation of cell division by light or temperature stimuli in the dimorphic yeast Schizosaccharomyces japonicus
Q33366517Systems biology of the clock in Neurospora crassa
Q41594576Temperature compensation and membrane composition in Neurospora crassa
Q34148145Temperature-modulated alternative splicing and promoter use in the Circadian clock gene frequency
Q41594615Temporal organization and disorganization in organisms
Q43167149Testing time: can ethanol-induced pulses of proposed oscillator components phase shift rhythms in Arabidopsis?
Q46361599The 2009 George W. Beadle Award
Q35943703The Arabidopsis thaliana clock.
Q33891920The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex
Q37312154The Ccr4-not protein complex regulates the phase of the Neurospora circadian clock by controlling white collar protein stability and activity
Q34495162The Circadian Clock Modulates Global Daily Cycles of mRNA Ribosome Loading
Q52566479The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex.
Q40472322The Genetic Basis of the Circadian Clock: Identification of frq and FRQ as Clock Components in Neurospora
Q33822181The Goodwin oscillator: on the importance of degradation reactions in the circadian clock
Q33970274The Mouse Clock Mutation Behaves as an Antimorph and Maps Within the W19H Deletion, Distal of Kit
Q28769790The Neurospora circadian clock: simple or complex?
Q34621726The Neurospora crassa circadian clock
Q33937081The PAS protein VIVID defines a clock-associated feedback loop that represses light input, modulates gating, and regulates clock resetting
Q34116972The PAS/LOV protein VIVID supports a rapidly dampened daytime oscillator that facilitates entrainment of the Neurospora circadian clock
Q34494860The aging biological clock in Neurospora crassa.
Q34638447The band mutation in Neurospora crassa is a dominant allele of ras-1 implicating RAS signaling in circadian output
Q71962383The biological clock: it's all in the genes
Q34195617The circadian clock of Neurospora crassa
Q33534304The circadian system of Arabidopsis thaliana: forward and reverse genetic approaches
Q48153892The cycling and distribution of PER-like antigen in relation to neurons recognized by the antisera to PTTH and EH in Thermobia domestica
Q35996334The exosome controls alternative splicing by mediating the gene expression and assembly of the spliceosome complex.
Q37409411The exosome regulates circadian gene expression in a posttranscriptional negative feedback loop
Q34617962The frequency gene is required for temperature-dependent regulation of many clock-controlled genes in Neurospora crassa
Q35377726The frequency natural antisense transcript first promotes, then represses, frequency gene expression via facultative heterochromatin
Q41304476The genetic and molecular dissection of a prototypic circadian system.
Q28595586The genetics of circadian rhythms in Neurospora
Q33698547The highly expressed methionine synthase gene of Neurospora crassa is positively regulated by its proximal heterochromatic region
Q34923968The histone H3 lysine 9 methyltransferase DIM-5 modifies chromatin at frequency and represses light-activated gene expression
Q47872541The late elongated hypocotyl mutation of Arabidopsis disrupts circadian rhythms and the photoperiodic control of flowering
Q34366330The neurospora circadian system
Q74248973The suprachiasmatic nucleus and the circadian time-keeping system revisited
Q52551579The timSL mutant of the Drosophila rhythm gene timeless manifests allele-specific interactions with period gene mutants.
Q52577729Theoretical models for circadian rhythms in Neurospora and Drosophila.
Q34426048Thermally regulated translational control of FRQ mediates aspects of temperature responses in the neurospora circadian clock
Q37141122Thermosensitive splicing of a clock gene and seasonal adaptation
Q33538734Time at the end of the millennium: the Neurospora clock
Q28215112Time zones: a comparative genetics of circadian clocks
Q38666224Timing in the Testis
Q38952667Timing the day: what makes bacterial clocks tick?
Q58746009Transcription factor CBF-1 is critical for circadian gene expression by modulating WHITE COLLAR complex recruitment to the frq locus
Q34561933Transcription of the major neurospora crassa microRNA-like small RNAs relies on RNA polymerase III
Q35945942Transcriptional control of circadian hormone synthesis via the CREM feedback loop
Q37140963Transcriptional feedback and definition of the circadian pacemaker in Drosophila and animals.
Q36344956Transcriptional repression of frequency by the IEC-1-INO80 complex is required for normal Neurospora circadian clock function
Q40443921Trippings along the trail to the molecular mechanisms of biological clocks
Q39538714Ubiquitin ligase components Cullin4 and DDB1 are essential for DNA methylation in Neurospora crassa
Q89000212Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1
Q36852230Unraveling the circadian clock in Arabidopsis
Q34135188VIVID interacts with the WHITE COLLAR complex and FREQUENCY-interacting RNA helicase to alter light and clock responses in Neurospora
Q24655563Vitamin B2-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals
Q33935905WC-2 mediates WC-1-FRQ interaction within the PAS protein-linked circadian feedback loop of Neurospora
Q50497025WHITE COLLAR-1, a multifunctional neurospora protein involved in the circadian feedback loops, light sensing, and transcription repression of wc-2.
Q90176856ZmCCA1a on Chromosome 10 of Maize Delays Flowering of Arabidopsis thaliana
Q42541521cAMP-dependent signaling as a core component of the mammalian circadian pacemaker
Q36561311per mRNA cycling is locked to lights-off under photoperiodic conditions that support circadian feedback loop function
Q40423311period and timeless Tango: A dance of two clock genes

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