Deconstructing myc.

scientific article

Deconstructing myc. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD928101
P698PubMed publication ID11511533
P5875ResearchGate publication ID11832996

P2093author name stringEisenman RN
P433issue16
P304page(s)2023-2030
P577publication date2001-08-01
P1433published inGenes & DevelopmentQ1524533
P1476titleDeconstructing myc.
P478volume15

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cites work (P2860)
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Q44220811E2F proteins regulate MYCN expression in neuroblastomas
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Q31013236Histone deacetylase activity is necessary for left-right patterning during vertebrate development
Q51595537Human Arf tumor suppressor specifically interacts with chromatin containing the promoter of rRNA genes.
Q33612813Hydra myc2, a unique pre-bilaterian member of the myc gene family, is activated in cell proliferation and gametogenesis
Q24681460Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1
Q35669176Identification of cis-Regulatory Elements in the dmyc Gene of Drosophila Melanogaster
Q40569139Identification of genes that are regulated transcriptionally by Myc in childhood tumors
Q38363958Identifying genes regulated in a Myc-dependent manner
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Q34619131In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential.
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Q35043420Induction of apoptosis in cancer: new therapeutic opportunities
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Q28656132Inhibitor of MYC identified in a Kröhnke pyridine library
Q28247124Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes
Q62839089Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis
Q41981890Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila
Q34989577Intracellular glycosylation and development
Q34564825Invited review: Effects of heat and cold stress on mammalian gene expression
Q33949883JAC, a direct target of oncogenic transcription factor Jun, is involved in cell transformation and tumorigenesis
Q64083382LAPTM4B is a novel diagnostic and prognostic marker for lung adenocarcinoma and associated with mutant EGFR
Q33382271Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual information
Q63407030Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma
Q39647656Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis
Q35056472Lymphoma- and leukemia-associated chromosomal translocations in healthy individuals
Q37485846MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation
Q36819401MAP kinases and the control of nuclear events
Q28250940MMTV mouse models and the diagnostic values of MMTV-like sequences in human breast cancer
Q51023212MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer.
Q38193043MYC degradation
Q39242259MYC expression and distribution in normal mature lymphoid cells.
Q35149681MYC regulates the non-coding transcriptome.
Q34288613MYC-regulated genes involved in liver cell dysplasia identified in a transgenic model of liver cancer
Q39149130MYC: Master Regulator of Immune Privilege
Q24535514Mad4 is regulated by a transcriptional repressor complex that contains Miz-1 and c-Myc
Q35096127Mammalian neural stem-cell renewal: nature versus nurture
Q34230052Members of the poly (rC) binding protein family stimulate the activity of the c-myc internal ribosome entry segment in vitro and in vivo
Q33812198MicroRNA 17-92 cluster mediates ETS1 and ETS2-dependent RAS-oncogenic transformation
Q42004179MicroRNA: Biogenesis, Function and Role in Cancer
Q35199251Miz-1 activates gene expression via a novel consensus DNA binding motif
Q36321695Mnt-Max to Myc-Max complex switching regulates cell cycle entry
Q31127154Molecular features of adult mouse small intestinal epithelial progenitors
Q24300934Multiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops
Q33248957Mutations in PIK3CA are infrequent in neuroblastoma
Q39776556Mutual interference of adenovirus infection and myc expression
Q41831140Mxi1-0, an alternatively transcribed Mxi1 isoform, is overexpressed in glioblastomas.
Q34074572Myc and Mad bHLHZ domains possess identical DNA-binding specificities but only partially overlapping functions in vivo
Q40495521Myc antagonizes Ras-mediated growth arrest in leukemia cells through the inhibition of the Ras-ERK-p21Cip1 pathway
Q34827156Myc degradation: dancing with ubiquitin ligases.
Q34766868Myc influences global chromatin structure.
Q41354231Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest
Q39688916Myc is required for the maintenance of Kaposi's sarcoma-associated herpesvirus latency
Q30480348Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1
Q24557458Myc represses transcription through recruitment of DNA methyltransferase corepressor
Q36149282Myc stimulates B lymphocyte differentiation and amplifies calcium signaling
Q38324237Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis
Q38290959Myc target in myeloid cells-1, a novel c-Myc target, recapitulates multiple c-Myc phenotypes
Q35054858Myc transcription factors: key regulators behind establishment and maintenance of pluripotency.
Q53380068Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.
Q28366366Myc/Max/Mad regulate the frequency but not the duration of productive cell cycles
Q28587989N-Myc and L-Myc are essential for hair cell formation but not maintenance
Q34830715N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development
Q36367230N-myc coordinates retinal growth with eye size during mouse development.
Q28207748N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
Q55014166NDRG3 facilitates colorectal cancer metastasis through activating Src phosphorylation.
Q28212421Negative regulation of the mammalian UV response by Myc through association with Miz-1
Q37697114Nerve growth factor modulates the tumor cells migration in ovarian cancer through the WNT/β-catenin pathway
Q28590740Neural crest cell deficiency of c-myc causes skull and hearing defects
Q24681926Neuregulin3 alters cell fate in the epidermis and mammary gland
Q37995989New frontiers in cell competition
Q26826854Nodal signaling promotes a tumorigenic phenotype in human breast cancer
Q40666241Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing
Q36233025Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability
Q40555942Omomyc expression in skin prevents Myc-induced papillomatosis
Q33789149On the identification of potential regulatory variants within genome wide association candidate SNP sets
Q42321596Oncogenic regulation of tumor metabolic reprogramming
Q40200588PML4 induces differentiation by Myc destabilization
Q28508508PRELI (protein of relevant evolutionary and lymphoid interest) is located within an evolutionarily conserved gene cluster on chromosome 5q34-q35 and encodes a novel mitochondrial protein
Q42811126Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression
Q35570730Perturbation of the c-Myc-Max protein-protein interaction via synthetic α-helix mimetics.
Q38336940Polyamine-modulated expression of c-myc plays a critical role in stimulation of normal intestinal epithelial cell proliferation
Q44366709Profiling of differentially expressed apoptosis-related genes by cDNA arrays in human cord blood CD34+ cells treated with etoposide
Q50692461Prognostic significance of MYCN gene amplification and protein expression in primary brain tumors: Astrocytoma and meningioma.
Q36216959Prognostic significance of Minichromosome maintenance protein 7 and Geminin expression in patients with 109 soft tissue sarcomas
Q33285211Proteome analysis of proliferative response of bystander cells adjacent to cells exposed to ionizing radiation
Q39658948Quantitative proteomic analysis of Myc oncoprotein function
Q73599437Quantitative proteomic analysis of chromatin-associated factors
Q53874874Recruitment of Gcn5-containing complexes during c-Myc-dependent gene activation. Structure and function aspects.
Q95811202Reduced expression of N-Myc downstream-regulated gene 2 in human thyroid cancer
Q34783510Regulation of N-myc expression in development and disease
Q40642721Regulation of c-myc gene by nitric oxide via inactivating NF-kappa B complex in P19 mouse embryonal carcinoma cells
Q28202238Repression of the TMEFF2 Promoter by c-Myc
Q40440846Retinoic acid-induced chromatin remodeling of mouse kappa opioid receptor gene.
Q36143495Role of Src family kinases and N-Myc in spermatogonial stem cell proliferation.
Q34852828Runx transcription factors repress human and murine c-Myc expression in a DNA-binding and C-terminally dependent manner
Q33654212Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer
Q33193145Solution‐Phase Combinatorial Libraries: Modulating Cellular Signaling by Targeting Protein–Protein or Protein–DNA Interactions
Q31157296Spatial distribution and function of sterol regulatory element-binding protein 1a and 2 homo- and heterodimers by in vivo two-photon imaging and spectroscopy fluorescence resonance energy transfer
Q33732822Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra
Q24810339Stimulation of Myc transactivation by the TATA binding protein in promoter-reporter assays
Q39987298Suppression of C-myc expression associates with anti-proliferation of aloe-emodin on gastric cancer cells
Q40731052Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.
Q39029986TGF-β Family Signaling in the Control of Cell Proliferation and Survival
Q24298315TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC
Q36002496TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription
Q28281008Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II-dependent pathway in human K562 leukemia cells
Q36132771Targeting c-MYC in Platinum-Resistant Ovarian Cancer
Q52728139The MYC oncogene is a global regulator of the immune response.
Q89766642The MYCL and MXD1 transcription factors regulate the fitness of murine dendritic cells
Q52655658The Myc trilogy: lord of RNA polymerases.
Q28295870The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60
Q28575753The c-Myc target gene Rcl (C6orf108) encodes a novel enzyme, deoxynucleoside 5'-monophosphate N-glycosidase
Q37013896The c-myc promoter: still MysterY and challenge
Q39000409The human papillomavirus E7 oncoprotein as a regulator of transcription
Q52104498The protooncogene c-myc is an essential regulator of neural crest formation in xenopus.
Q38975478The role of c2orf68 and PI3K/Akt/mTOR pathway in human colorectal cancer
Q33924983The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster
Q37644952The ups and downs of Myc biology
Q35804087Thermal stress and the disruption of redox-sensitive signalling and transcription factor activation: possible role in radiosensitization
Q28190719Tissue-specific nuclear architecture and gene expression regulated by SATB1
Q34932264Transcription factors as targets for cancer therapy
Q39048077Transcriptional control of DNA replication licensing by Myc.
Q36215755Transcriptional regulation and transformation by Myc proteins
Q24537716Transcriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexes
Q35082149Transcriptional repression by Myc.
Q24629916Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element
Q36162197Transforming growth factor-β activates c-Myc to promote palatal growth.
Q41208913Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail.
Q40399589Upregulation of a functional form of the beta4 integrin subunit in colorectal cancers correlates with c-Myc expression
Q48424196WS5, a direct target of oncogenic transcription factor Myc, is related to human melanoma glycoprotein genes and has oncogenic potential.
Q33758260Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxes
Q91940275Writing and erasing MYC ubiquitination and SUMOylation
Q24316949c-MYC activates protein kinase A (PKA) by direct transcriptional activation of the PKA catalytic subunit beta (PKA-Cbeta) gene
Q37620912c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
Q42115767c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle
Q28583514c-Myc directly regulates the transcription of the NBS1 gene involved in DNA double-strand break repair
Q33925138c-Myc is required for the formation of intestinal crypts but dispensable for homeostasis of the adult intestinal epithelium
Q35087557c-Myc regulates cell proliferation during lens development
Q28186628c-Myc transformation domain recruits the human STAGA complex and requires TRRAP and GCN5 acetylase activity for transcription activation
Q35222270c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3.
Q47072112dMyc transforms cells into super-competitors
Q73642456jumonji downregulates cardiac cell proliferation by repressing cyclin D1 expression
Q24679145mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad