review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Rainer J. Klement | Q56073415 |
P2860 | cites work | Is there a role for carbohydrate restriction in the treatment and prevention of cancer? | Q21245058 |
Cancer as a metabolic disease | Q21245061 | ||
Metabolic effects of the very-low-carbohydrate diets: misunderstood "villains" of human metabolism | Q21245431 | ||
Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C | Q24315840 | ||
HIF-1: upstream and downstream of cancer metabolism | Q24647482 | ||
AKT/PKB signaling: navigating downstream | Q24657857 | ||
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck | Q24674610 | ||
Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)? | Q26864685 | ||
Fasting enhances the response of glioma to chemo- and radiotherapy | Q27320014 | ||
On the Origin of Cancer Cells | Q27861025 | ||
Pretreatment prognostic factors for survival in small-cell lung cancer: a new prognostic index and validation of three known prognostic indices on 341 patients | Q28246500 | ||
Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer | Q28488474 | ||
A unique glucose-dependent apoptotic pathway induced by c-Myc | Q28575560 | ||
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation | Q29547301 | ||
THE METABOLISM OF TUMORS IN THE BODY | Q29616202 | ||
Insulin and insulin-like growth factor signalling in neoplasia | Q29619495 | ||
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice | Q30080001 | ||
Elevated glucose and diabetes promote interleukin-12 cytokine gene expression in mouse macrophages | Q30439419 | ||
Changes in nutritional status and dietary intake during and after head and neck cancer treatment | Q59658030 | ||
In vivo nutrient uptake by head and neck cancers | Q69204812 | ||
Oxidation of branched chain amino acids by isolated hearts and diaphragms of the rat. The effect of fatty acids, glucose, and pyruvate respiration | Q69392561 | ||
The oxidation of body fuel stores in cancer patients | Q69683369 | ||
The inhibitory effect of various fatty acids on aerobic glycolysis in Ehrlich ascites tumour cells | Q69995759 | ||
Cancer cachexia: influence of systemic ketosis on substrate levels and nitrogen metabolism | Q70372355 | ||
Patterns of nutritional deficiency in head and neck cancer | Q70438871 | ||
Different contribution of substrates oxidation to insulin resistance in malnourished elderly patients with cancer | Q72559266 | ||
Epigenetic changes of tumor suppressor genes, P15, P16, VHL and P53 in oral cancer | Q73235591 | ||
Energy intake and prostate tumor growth, angiogenesis, and vascular endothelial growth factor expression | Q74628191 | ||
Circulating interleukin 6 concentrations and insulin resistance in patients with cancer | Q77755376 | ||
[Comparative study of the administration of anabolic amino acids. Confirms the discovery of the Master Amino Acid Pattern] | Q77773279 | ||
Norms and correlates of bioimpedance phase angle in healthy human subjects, hospitalized patients, and patients with liver cirrhosis | Q77910046 | ||
Effect of energy substrate manipulation on tumour cell proliferation in parenterally fed cancer patients | Q79900533 | ||
Overexpression of transketolase TKTL1 is associated with shorter survival in laryngeal squamous cell carcinomas | Q80637346 | ||
High-protein diets: putting rumors to rest | Q80820433 | ||
Bioelectrical impedance phase angle in clinical practice: implications for prognosis in advanced colorectal cancer | Q81111203 | ||
Impact of nutrition support on treatment outcome in patients with locally advanced head and neck squamous cell cancer treated with definitive radiotherapy: a secondary analysis of RTOG trial 90-03 | Q81478502 | ||
Clinical utility of 18F-FDG PET parameters in patients with advanced nasopharyngeal carcinoma: predictive role for different survival endpoints and impact on prognostic stratification | Q84814008 | ||
Lean body mass and muscle function in head and neck cancer patients and healthy individuals--results from the DAHANCA 25 study | Q87289278 | ||
The insulin and insulin-like growth factor receptor family in neoplasia: an update | Q37984217 | ||
Targeting hypoxia, HIF-1, and tumor glucose metabolism to improve radiotherapy efficacy. | Q38052537 | ||
Muscle wasting in cancer | Q38114714 | ||
Selectively starving cancer cells through dietary manipulation: methods and clinical implications | Q38120308 | ||
Effect of nutritional interventions on nutritional status, quality of life and mortality in patients with head and neck cancer receiving (chemo)radiotherapy: a systematic review | Q38120869 | ||
Nutritional considerations for head and neck cancer patients: a review of the literature | Q38120906 | ||
Targeting lactate metabolism for cancer therapeutics | Q38133722 | ||
Early recognition of malnutrition and cachexia in the cancer patient: a position paper of a European School of Oncology Task Force | Q38191161 | ||
Nutrition and the head and neck cancer patient | Q38235635 | ||
Pten-null tumors cohabiting the same lung display differential AKT activation and sensitivity to dietary restriction. | Q38449970 | ||
Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells | Q39132009 | ||
Fluorodeoxyglucose-positron-emission tomography imaging of head and neck squamous cell cancer | Q30884020 | ||
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer | Q31011148 | ||
Clinical significance in oral cavity squamous cell carcinoma of pathogenic somatic mitochondrial mutations | Q31120276 | ||
Bioelectrical impedance phase angle as a prognostic indicator in breast cancer | Q33363467 | ||
Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report | Q33562229 | ||
Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis | Q33623036 | ||
TKTL1 is activated by promoter hypomethylation and contributes to head and neck squamous cell carcinoma carcinogenesis through increased aerobic glycolysis and HIF1alpha stabilization | Q33668662 | ||
Clinical update on cancer: molecular oncology of head and neck cancer | Q33695197 | ||
The glucose metabolism of patients with malignant disease and of normal subjects as studied by means of an intravenous glucose tolerance test | Q33731637 | ||
ERGO: a pilot study of ketogenic diet in recurrent glioblastoma | Q33778107 | ||
Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism? | Q33948122 | ||
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy | Q33972116 | ||
Alterations of nutritional status.Impact of chemotherapy and radiation therapy | Q33986111 | ||
Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L) | Q34018022 | ||
Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review | Q34028478 | ||
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy | Q34030634 | ||
FDG-PET staging and importance of lymph node SUV in head and neck cancer | Q34043837 | ||
Cancer proliferation and therapy: the Warburg effect and quantum metabolism | Q34093618 | ||
Definition and classification of cancer cachexia: an international consensus | Q34162846 | ||
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma | Q34174680 | ||
Ketoacids? Good medicine? | Q34206876 | ||
The ketogenic diet for the treatment of glioma: insights from genetic profiling | Q34226470 | ||
Ketone bodies as signaling metabolites. | Q34252732 | ||
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor | Q34316485 | ||
Counseling patients on cancer diets: a review of the literature and recommendations for clinical practice | Q34396609 | ||
Metabolic imaging: a link between lactate dehydrogenase A, lactate, and tumor phenotype | Q34440549 | ||
Body composition and hormonal responses to a carbohydrate-restricted diet | Q34524410 | ||
A biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells | Q34529496 | ||
Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer. | Q34554818 | ||
Clinically defined type 2 diabetes mellitus and prognosis in early-stage breast cancer | Q34662865 | ||
LKB1 and AMPK and the cancer-metabolism link - ten years after | Q34669215 | ||
Effects of a ketogenic diet on tumor metabolism and nutritional status in pediatric oncology patients: two case reports | Q34722625 | ||
The ketogenic diet for the treatment of malignant glioma | Q34757474 | ||
Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors. | Q39425252 | ||
Dietary recommendations during and after cancer treatment: consistently inconsistent? | Q39444965 | ||
Glucose deprivation activates AMPK and induces cell death through modulation of Akt in ovarian cancer cells | Q39542918 | ||
HDAC2 promotes cell migration/invasion abilities through HIF-1α stabilization in human oral squamous cell carcinoma. | Q39589749 | ||
Glycolytic metabolism and tumour response to fractionated irradiation. | Q39758697 | ||
Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression | Q39761800 | ||
Ketone bodies inhibit the viability of human neuroblastoma cells. | Q39892401 | ||
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation | Q39927250 | ||
Rapid loss of ATP by tumor cells deprived of glucose: Contrast to normal cells | Q40176533 | ||
Tumor lactate content predicts for response to fractionated irradiation of human squamous cell carcinomas in nude mice. | Q40231967 | ||
Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis | Q40404693 | ||
Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells. | Q40488586 | ||
Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors | Q40522541 | ||
High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells | Q40652063 | ||
Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia | Q40835443 | ||
Loss of acetoacetate coenzyme A transferase activity in tumours of peripheral tissues | Q41506230 | ||
Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2. | Q41550485 | ||
TIGAR, TIGAR, burning bright. | Q41872025 | ||
Ketolytic and glycolytic enzymatic expression profiles in malignant gliomas: implication for ketogenic diet therapy | Q41895412 | ||
Systemic elevation of PTEN induces a tumor-suppressive metabolic state | Q41968721 | ||
Ketosis and Nitrogen Excretion in Undernourished Surgical Patients | Q42143913 | ||
Increased lipid utilization in weight losing and weight stable cancer patients with normal body weight | Q42478295 | ||
Tissue electric properties in head and neck cancer patients. | Q42486202 | ||
Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression | Q42554040 | ||
Effects of ketone bodies on amino acid metabolism in isolated rat diaphragm | Q42917101 | ||
Calorie or carbohydrate restriction? The ketogenic diet as another option for supportive cancer treatment. | Q42971350 | ||
Prescribing practice and evaluation of appropriateness of enteral nutrition in a university teaching hospital | Q43237800 | ||
Lactate dehydrogenase 5 expression in squamous cell head and neck cancer relates to prognosis following radical or postoperative radiotherapy | Q43239152 | ||
Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats. | Q43458889 | ||
Insulin resistance in patients with cancer: relationships with tumor site, tumor stage, body-weight loss, acute-phase response, and energy expenditure | Q43670557 | ||
Serial positron emission tomography scans following radiation therapy of patients with head and neck cancer | Q43831803 | ||
Standardized uptake value of 2-[(18)F] fluoro-2-deoxy-D-glucose in predicting outcome in head and neck carcinomas treated by radiotherapy with or without chemotherapy | Q43899661 | ||
Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients | Q44266484 | ||
Persistent outpatient hyperglycemia is independently associated with decreased survival after primary resection of malignant brain astrocytomas | Q44281661 | ||
Decline of lactate in tumor tissue after ketogenic diet: in vivo microdialysis study in patients with head and neck cancer. | Q44415605 | ||
Diabetes and oral tumors in Hungary: epidemiological correlations | Q44779330 | ||
Relation between the duration of remission and hyperglycemia during induction chemotherapy for acute lymphocytic leukemia with a hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone/methotrexate-cytarabine regimen | Q44800298 | ||
A disease-specific enteral nutrition formula improves nutritional status and functional performance in patients with head and neck and esophageal cancer undergoing chemoradiotherapy: results of a randomized, controlled, multicenter trial | Q44840769 | ||
Prediction of outcome in head-and-neck cancer patients using the standardized uptake value of 2-[18F]fluoro-2-deoxy-D-glucose | Q44994021 | ||
JunD reduces tumor angiogenesis by protecting cells from oxidative stress | Q45060498 | ||
Prognostic value of 18F-FDG PET in patients with head and neck squamous cell cancer | Q46079321 | ||
Tumor cell culture survival following glucose and glutamine deprivation at typical physiological concentrations. | Q46691566 | ||
Effects of a high-fat diet on body composition in cancer patients receiving chemotherapy: a randomized controlled study | Q46896505 | ||
High fasting blood glucose and obesity significantly and independently increase risk of breast cancer death in hormone receptor-positive disease. | Q48930446 | ||
The influence of plasma glucose levels on fluorine-18-fluorodeoxyglucose uptake in bronchial carcinomas. | Q51601704 | ||
Serum tumour necrosis factor alpha and insulin resistance in gastrointestinal cancer. | Q51603092 | ||
Glucose intolerance in sarcoma patients. | Q51640423 | ||
Prognostic value of (18)F-fluorodeoxyglucose uptake before treatment for pharyngeal cancer. | Q53079718 | ||
Imaging tumor perfusion and oxidative metabolism in patients with head-and-neck cancer using 1- [11C]-acetate PET during radiotherapy: preliminary results. | Q53249940 | ||
The inhibition of malignant cell growth by ketone bodies | Q53580986 | ||
Altered tissue electric properties in lung cancer patients as detected by bioelectric impedance vector analysis. | Q54060917 | ||
Insulin resistance in cancer patients is associated with enhanced tumor necrosis factor-alpha expression in skeletal muscle. | Q54107369 | ||
Insulin resistance in patients with cancer. | Q54578043 | ||
The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer | Q34766593 | ||
The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas | Q34785613 | ||
Mitochondrial DNA mutations in head and neck cancer are infrequent and lack prognostic utility | Q34806878 | ||
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells | Q35103648 | ||
Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial | Q35168645 | ||
Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms. | Q35558846 | ||
Mitochondrial energetics and therapeutics | Q35632864 | ||
The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism | Q35652475 | ||
Dietary restriction promotes vessel maturation in a mouse astrocytoma. | Q35664431 | ||
Correlation of high lactate levels in head and neck tumors with incidence of metastasis | Q35764703 | ||
Lactate: mirror and motor of tumor malignancy | Q35837050 | ||
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death | Q36096600 | ||
Ketogenic diet does not affect strength performance in elite artistic gymnasts. | Q36138650 | ||
Impact of diabetes and hyperglycemia on survival in advanced breast cancer patients | Q36165176 | ||
Ketone body therapy: from the ketogenic diet to the oral administration of ketone ester | Q36197639 | ||
ESPEN Guidelines on Enteral Nutrition: Non-surgical oncology. | Q36477266 | ||
Nutrient restriction and radiation therapy for cancer treatment: when less is more | Q36565675 | ||
Epigenetic mechanisms in oral carcinogenesis. | Q36602726 | ||
The regulation of cellular metabolism by tumor suppressor p53. | Q36614219 | ||
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. | Q36751440 | ||
Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer | Q36906195 | ||
Caloric restriction augments radiation efficacy in breast cancer | Q37075928 | ||
Indications for PET/CT in the head and neck. | Q37080261 | ||
Glucose as a prognostic factor in ovarian carcinoma | Q37114344 | ||
Impact of targeting insulin-like growth factor signaling in head and neck cancers. | Q37126107 | ||
The Roles of SIRT1 in Cancer | Q37150510 | ||
Association between hyperglycemia and survival in patients with newly diagnosed glioblastoma | Q37155599 | ||
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma | Q37311021 | ||
Cancer as a metabolic disease: implications for novel therapeutics | Q37616057 | ||
Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts | Q37637990 | ||
Impact of obesity on the survival of patients with early-stage squamous cell carcinoma of the oral tongue | Q37652901 | ||
Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R's through dietary manipulation | Q37705691 | ||
The molecular biology of head and neck cancer | Q37821229 | ||
Biology of vascular endothelial growth factor and its receptors in head and neck cancer: beyond angiogenesis | Q37900923 | ||
Lactate: a metabolic key player in cancer | Q37956296 | ||
P433 | issue | 3 | |
P304 | page(s) | 145-161 | |
P577 | publication date | 2014-09-01 | |
P1433 | published in | Cancer Biology & Medicine | Q26841841 |
P1476 | title | Restricting carbohydrates to fight head and neck cancer-is this realistic? | |
P478 | volume | 11 |