Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A.

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Repression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/DEV.109306
P932PMC publication ID4197705
P698PubMed publication ID25231760
P5875ResearchGate publication ID265860639

P50authorWei LiQ75211121
Trudi SchüpbachQ92731521
P2093author name stringMartha Klovstad
P2860cites workA genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathwayQ24545061
The eIF1A solution structure reveals a large RNA-binding surface important for scanning functionQ27621444
Interaction between eukaryotic initiation factors 1A and 5B is required for efficient ribosomal subunit joining.Q27930734
Coupled release of eukaryotic translation initiation factors 5B and 1A from 80S ribosomes following subunit joining.Q27939079
Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexesQ27939264
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signalingQ28117922
Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particlesQ28296497
The mechanism of eukaryotic translation initiation and principles of its regulationQ29547270
The dynamics of fluorescently labeled endogenous gurken mRNA in DrosophilaQ30481743
Drosophila patterning is established by differential association of mRNAs with P bodiesQ30581234
Drosophila brca2 is required for mitotic and meiotic DNA repair and efficient activation of the meiotic recombination checkpointQ33319284
Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.Q33447106
The meiotic recombination checkpoint suppresses NHK-1 kinase to prevent reorganisation of the oocyte nucleus in Drosophila.Q33741945
VASA mediates translation through interaction with a Drosophila yIF2 homolog.Q33890379
Juxtaposition of C(2)M and the transverse filament protein C(3)G within the central region of Drosophila synaptonemal complex.Q33934493
The eIF1A C-terminal domain promotes initiation complex assembly, scanning and AUG selection in vivoQ34116876
Multiple mechanisms collaborate to repress nanos translation in the Drosophila ovary and embryoQ34807963
c(3)G encodes a Drosophila synaptonemal complex proteinQ35082997
Specific isoforms of squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesisQ35193203
okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesisQ35209095
Isolation of polysome-bound mRNA from solid tissues amenable for RT-PCR and profiling experiments.Q35641241
Modulation of gurken translation by insulin and TOR signaling in DrosophilaQ35912441
mRNA localization and translational control in Drosophila oogenesisQ36329472
Squid, Cup, and PABP55B function together to regulate gurken translation in DrosophilaQ36512853
Cellular responses to DNA damage: one signal, multiple choicesQ36521810
Drosophila PCH2 is required for a pachytene checkpoint that monitors double-strand-break-independent events leading to meiotic crossover formationQ37052363
Kinetic analysis of late steps of eukaryotic translation initiationQ37124823
An essential role of DmRad51/SpnA in DNA repair and meiotic checkpoint controlQ37368057
Regulation of protein synthesis by ionizing radiation.Q37410747
p53/TAp63 and AKT regulate mammalian target of rapamycin complex 1 (mTORC1) signaling through two independent parallel pathways in the presence of DNA damageQ37583480
Translational Regulation of Gene Expression during Conditions of Cell StressQ37802038
The molecular control of meiotic chromosomal behavior: events in early meiotic prophase in Drosophila oocytesQ37984133
The scanning mechanism of eukaryotic translation initiationQ38185457
Translation initiation factor eIF4E is a target for tumor cell radiosensitization.Q39383867
The drosophila dorsoventral patterning gene gurken produces a dorsally localized RNA and encodes a TGFα-like proteinQ41064456
cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in DrosophilaQ47070457
Initial organization of the Drosophila dorsoventral axis depends on an RNA-binding protein encoded by the squid geneQ47070855
Encore is a member of a novel family of proteins and affects multiple processes in Drosophila oogenesisQ47071430
Localization-dependent oskar protein accumulation; control after the initiation of translationQ47072521
Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesisQ47843860
Translational repression of gurken mRNA in the Drosophila oocyte requires the hnRNP Squid in the nurse cellsQ48731009
Drosophila Squid/hnRNP helps Dynein switch from a gurken mRNA transport motor to an ultrastructural static anchor in sponge bodiesQ48776623
Activation of a meiotic checkpoint during Drosophila oogenesis regulates the translation of Gurken through Chk2/MnkQ48849499
Functioning of the Drosophila orb gene in gurken mRNA localization and translationQ48875122
Me31B silences translation of oocyte-localizing RNAs through the formation of cytoplasmic RNP complex during Drosophila oogenesis.Q48879812
Activation of a meiotic checkpoint regulates translation of Gurken during Drosophila oogenesisQ48905784
Polarization of both major body axes in Drosophila by gurken-torpedo signallingQ49049269
The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarityQ49113524
Interaction with eIF5B is essential for Vasa function during development.Q50797471
Synthesis of the posterior determinant Nanos is spatially restricted by a novel cotranslational regulatory mechanism.Q52163163
Translational regulation of mRNAs for ribosomal proteins during early Drosophila development.Q52466558
Relationship of DNA double-strand breaks to synapsis in Drosophila.Q52608121
Ultraviolet light inhibits translation through activation of the unfolded protein response kinase PERK in the lumen of the endoplasmic reticulumQ77725784
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P1104number of pages12
P304page(s)3910-3921
P577publication date2014-09-17
P1433published inDevelopmentQ3025404
P1476titleRepression of Gurken translation by a meiotic checkpoint in Drosophila oogenesis is suppressed by a reduction in the dose of eIF1A
P478volume141

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cites work (P2860)
Q36174462Lifespan and Stress Resistance in Drosophila with Overexpressed DNA Repair Genes
Q36773353Localized Translation of gurken/TGF-α mRNA during Axis Specification Is Controlled by Access to Orb/CPEB on Processing Bodies
Q47988457Multiple Functions of the DEAD-Box Helicase Vasa in Drosophila Oogenesis
Q36210184The Histone Deacetylase Gene Rpd3 Is Required for Starvation Stress Resistance
Q39007668Translational control of gurken mRNA in Drosophila development.
Q48572838Wispy and Orb cooperate in the cytoplasmic polyadenylation of localized gurken mRNA.
Q36622371Zfrp8 forms a complex with fragile-X mental retardation protein and regulates its localization and function

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