"Second hit" models of alcoholic liver disease.

scientific article

"Second hit" models of alcoholic liver disease. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1055/S-0029-1214373
P932PMC publication ID4197797
P698PubMed publication ID19387917

P50authorKeigo MachidaQ41371039
P2093author name stringHidekazu Tsukamoto
Hasmik Mkrtchyan
Alla Dynnyk
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Plasma levels of a novel noncyclooxygenase-derived prostanoid (8-isoprostane) correlate with severity of liver injury in experimental alcoholic liver diseaseQ72023092
Hepatic fibrosis produced in guinea pigs by chronic ethanol administration and immunization with acetaldehyde adductsQ72210597
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Dietary carbohydrate intake plays an important role in preventing alcoholic fatty liver in the ratQ77619522
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Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulationQ81294978
Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liverQ83182716
Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injuryQ36645721
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in miceQ36688699
Hepatic macrophage iron aggravates experimental alcoholic steatohepatitisQ36877259
Repeated whiskey binges promote liver injury in rats fed a choline-deficient dietQ36925263
Endoplasmic reticulum stress and liver injuryQ36989688
Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liverQ37001200
Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1Q37111703
Contribution of the sympathetic hormone epinephrine to the sensitizing effect of ethanol on LPS-induced liver damage in miceQ37139288
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injuryQ38291198
Leptin deficiency enhances sensitivity of rats to alcoholic steatohepatitis through suppression of metallothioneinQ38335556
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed miceQ38354947
Zinc metabolism in alcoholic liver diseaseQ39757000
Hepatic effects of acetaminophen. Enhanced toxicity in alcoholicsQ39765074
Relationship of ethanol to choline metabolism in the liver: a reviewQ39900423
Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver diseaseQ40010594
Effects of triglyceride on ER stress and insulin resistanceQ40080488
Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.Q40474758
Regulation of hepatic microsomal cytochrome P450IIE1 level by dietary lipids and carbohydrates in ratsQ41187799
Incomplete compensation of enhanced hepatic oxygen consumption in rats with alcoholic centrilobular liver necrosisQ41349177
Iron primes hepatic macrophages for NF-kappaB activation in alcoholic liver injuryQ41708777
Lysosomal leakage and lack of adaptation of hepatoprotective enzyme contribute to enhanced susceptibility to ethanol-induced liver injury in female ratsQ42518667
The swift increase in alcohol metabolism. Time course for the increase in hepatic oxygen uptake and the involvement of glycolysisQ42879983
Experimental liver cirrhosis induced by alcohol and ironQ42929412
Molecular basis for the synergy between alcohol and hepatitis C virus in hepatocarcinogenesisQ42977104
Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesisQ43031864
Gender differences in pharmacokinetics of alcoholQ43592740
Liver necrosis induced by thyroid hormone administration in rats fed ethanolQ43705073
Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damageQ44042283
Estrogen increases sensitivity of hepatic Kupffer cells to endotoxinQ44298573
Ethanol-induced liver fibrosis in rats fed high fat dietQ44542773
Alcohol-induced liver injury in mice lacking Cu, Zn-superoxide dismutaseQ44632307
Ethanol binging exacerbates sinusoidal endothelial and parenchymal injury elicited by acetaminophenQ45264409
Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosisQ45733913
Nuclear factor-eythroid 2-related factor 2 prevents alcohol-induced fulminant liver injuryQ46090988
Role of iron in NF-kappa B activation and cytokine gene expression by rat hepatic macrophagesQ46362946
Experimental hepatitis induced by ethanol after immunization with acetaldehyde adductsQ46461084
Fish oil fed prior to ethanol administration prevents acute ethanol-induced fatty liver in miceQ46488022
A voluntary oral ethanol-feeding rat model associated with necroinflammatory liver injuryQ46701446
Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of ethanolQ46734486
IL-6-deficient mice are susceptible to ethanol-induced hepatic steatosis: IL-6 protects against ethanol-induced oxidative stress and mitochondrial permeability transition in the liver.Q46747521
S-adenosyl-L-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model.Q46818781
Female rats exhibit greater susceptibility to early alcohol-induced liver injury than males.Q50952813
Endotoxin induced hepatic necrosis in rats on an alcohol diet.Q54765276
Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinomaQ62727088
P433issue2
P304page(s)178-187
P577publication date2009-04-22
P1433published inSeminars in Liver DiseaseQ15724477
P1476title"Second hit" models of alcoholic liver disease
P478volume29

Reverse relations

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