The regulatory role of nitric oxide in apoptosis

scientific article

The regulatory role of nitric oxide in apoptosis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1567-5769(01)00088-1
P698PubMed publication ID11515809

P2093author name stringBilliar TR
Zamora R
Kim PK
Petrosko P
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Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxideQ28373485
Inhibition of endogenous nitric oxide synthase potentiates ischemia-reperfusion-induced myocardial apoptosis via a caspase-3 dependent pathwayQ28373853
Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cellsQ28375380
Nitric oxide mediates cyclosporine-induced apoptosis in cultured renal cellsQ28376515
Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytesQ28377454
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Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cellsQ33179554
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Regulation of cytosolic guanylyl cyclase by nitric oxide: the NO-cyclic GMP signal transduction systemQ40624472
Redox signaling: nitrosylation and related target interactions of nitric oxideQ40630842
Ceramide generation in nitric oxide-induced apoptosis. Activation of magnesium-dependent neutral sphingomyelinase via caspase-3.Q40819034
Trauma increases extrahepatic arginase activityQ40884869
Expression of a functional inducible nitric oxide synthase in hairy cell leukaemia and ESKOL cell line.Q40887161
Helicobacter pylori induces apoptosis in gastric epithelial cells through inducible nitric oxideQ40891200
Protective effect of thioredoxin upon NO-mediated cell injury in THP1 monocytic human cellsQ40896632
Activation of c-Ha-Ras by nitric oxide modulates survival responsiveness in neuronal PC12 cellsQ40911574
p53 accumulation in apoptotic macrophages is an energy demanding process that precedes cytochrome c release in response to nitric oxideQ40912284
Nitric oxide induces tyrosine nitration and release of cytochrome c preceding an increase of mitochondrial transmembrane potential in macrophages.Q40912921
Fas-induced caspase denitrosylationQ40958925
Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicityQ40972249
Arginase II downregulates nitric oxide (NO) production and prevents NO-mediated apoptosis in murine macrophage-derived RAW 264.7 cellsQ40974366
Resistance to nitric oxide-mediated apoptosis in HL-60 variant cells is associated with increased activities of Cu,Zn-superoxide dismutase and catalaseQ40979238
Redox generation of nitric oxide to radiosensitize hypoxic cellsQ40989741
The role of prostaglandin E2 and nitric oxide in cell death in J774 murine macrophagesQ41024024
Glutathione levels determine apoptosis in macrophagesQ41030712
Cyclic adenosine monophosphate inhibits nitric oxide-induced apoptosis in human leukemic HL-60 cellsQ41044778
Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signalQ41059135
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.Q41067625
Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liverQ41104171
Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathwaysQ41163068
Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivationQ41408037
p53 expression in nitric oxide‐induced apoptosisQ41428409
DNA damage induced by peroxynitrite: subsequent biological effectsQ41688617
Role of nitric oxide in mediation of macrophage cytotoxicity and apoptosis.Q41739523
Therapy of cancer metastasis by activation of the inducible nitric oxide synthaseQ41739528
Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucoseQ41827439
Nitric oxide causes apoptosis in pulmonary vascular smooth muscle cells.Q42461950
Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cellsQ42477721
Critical role of nitric oxide for proliferation and apoptosis of bone-marrow cells under septic conditionsQ42489781
Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cellsQ42536900
Dopamine-induced apoptosis is mediated by oxidative stress and Is enhanced by cyanide in differentiated PC12 cellsQ33180409
Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathwayQ33180653
Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanismQ33180727
Nitric oxide and mitochondrial respirationQ33631341
Poly (ADP-ribose) polymerase, nitric oxide and cell deathQ33633084
The role of nitric oxide in articular cartilage damageQ33651389
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S-nitrosylation of proteinsQ33708021
Novel aspects of Ras proteins biology: regulation and implications.Q33722647
The anti-apoptotic actions of nitric oxide in hepatocytesQ33771659
Mitochondrial membrane permeabilization during the apoptotic processQ33834219
Regulation of transglutaminases by nitric oxideQ33834230
Corpse clearance defines the meaning of cell deathQ33922730
Apoptotic pathways: paper wraps stone blunts scissorsQ33993406
Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylationQ34065605
An induced proximity model for caspase-8 activation.Q34065853
Defying death after DNA damage.Q34068957
Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutaseQ35042527
Nitric oxide is an important mediator for tumoricidal activity in vivoQ35786181
The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death.Q35851325
Chondrocyte-derived apoptotic bodies and calcification of articular cartilageQ35979737
The role of nitric oxide in bacillus Calmette-Guérin mediated anti-tumour effects in human bladder cancerQ36115320
Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxideQ36230415
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cellsQ36364685
A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in isletsQ36375424
Disruption of fas receptor signaling by nitric oxide in eosinophils.Q36400192
Nitric oxide enhancement of melphalan-induced cytotoxicityQ36423037
Nitric oxide activates cyclooxygenase enzymes.Q36457941
Role of nitric oxide synthesis in macrophage antimicrobial activityQ36656920
Impaired liver regeneration in inducible nitric oxide synthasedeficient miceQ36799802
Apoptosis of human intestinal epithelial cells after bacterial invasionQ37387961
Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cellsQ37628594
Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53.Q37694644
Biosynthesis and metabolism of endothelium-derived nitric oxideQ37925395
Attenuation of macrophage apoptosis by the cAMP-signaling systemQ38306015
Macrophage-derived nitric oxide induces apoptosis of rat hepatoma cells in vivoQ42538048
Transfection of inducible nitric oxide synthase gene causes apoptosis in vascular smooth muscle cells.Q42539605
Nitric oxide-dependent production of cGMP supports the survival of rat embryonic motor neurons cultured with brain-derived neurotrophic factor.Q42542845
Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanismsQ42546244
The formation of nitric oxide donors from peroxynitriteQ42708535
Production of nitric oxide by mitochondriaQ44987212
Purification of a Ca2+/calmodulin-dependent nitric oxide synthase from porcine cerebellum. Cofactor-role of tetrahydrobiopterinQ45279535
Nitric oxide exposure inhibits induction of lymphokine-activated killer cells by inducing precursor apoptosisQ47677131
Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharideQ47903820
Intracellular redox state determines whether nitric oxide is toxic or protective to rat oligodendrocytes in cultureQ48149140
Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP.Q48328674
Oxygen-glucose deprivation induces inducible nitric oxide synthase and nitrotyrosine expression in cerebral endothelial cells.Q50510912
The effect of nitric oxide and peroxynitrite on apoptosis in human polymorphonuclear leukocytes.Q51494417
Direct evidence of nitric oxide presence within mitochondria.Q51976323
Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent.Q52404730
Peroxynitrite formed by simultaneous nitric oxide and superoxide generation causes cyclosporin-A-sensitive mitochondrial calcium efflux and depolarisation.Q52518140
Protective effect of deferoxamine on sodium nitroprusside-induced apoptosis in PC12 cells.Q52531002
Tumor necrosis factor-alpha plus actinomycin D-induced apoptosis of L929 cells is prevented by nitric oxide.Q52574189
p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells.Q53428375
The Fpg protein, a DNA repair enzyme, is inhibited by the biomediator nitric oxide in vitro and in vivo.Q53469582
Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria.Q53904848
The p75(NTR)-induced apoptotic program develops through a ceramide-caspase pathway negatively regulated by nitric oxide.Q54095416
Effects of exogenous nitric oxide and hyperoxia on lung fibroblast viability and DNA fragmentation.Q54567445
Helicobacter pylori extract stimulates inflammatory nitric oxide production.Q54576512
S-nitrosylation regulates apoptosis.Q55067140
Inhibition of 20-HETE production contributes to the vascular responses to nitric oxideQ57221409
Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosisQ57773636
Activation of the Cell Death Program by Nitric Oxide Involves Inhibition of the ProteasomeQ58376437
Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cellsQ58486867
A cellular poison cupboardQ59060496
Mitochondrial Nitric-oxide Synthase Stimulation Causes CytochromecRelease from Isolated MitochondriaQ60532716
Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthaseQ62003460
Nitric Oxide Inhibits Caspase-3 byS-Nitrosationin VivoQ63303725
IL-1beta-induced apoptosis in rat gastric enterochromaffin-like cells is mediated by iNOS, NF-kappaB, and Bax proteinQ63407019
Protection of human islets from the effects of interleukin-1beta by adenoviral gene transfer of an Ikappa B repressorQ64380492
Cytokine-Induced Nitric Oxide Inhibits Bone Resorption by Inducing Apoptosis of Osteoclast Progenitors and Suppressing Osteoclast ActivityQ64448955
Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x.Q64935857
Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.Q64975773
L-arginine-dependent formation of N-nitrosamines by the cytosol of macrophages activated with lipopolysaccharide and interferon-gammaQ67694410
Posttranslational modification of glyceraldehyde-3-phosphate dehydrogenase by S-nitrosylation and subsequent NADH attachmentQ71070604
The nitric oxide donors, azide and hydroxylamine, inhibit the programmed cell death of cytokine-deprived human eosinophilsQ71684278
Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expressionQ71973760
Inducible nitric oxide synthetase is expressed in adult but not fetal pig pancreatic isletsQ73047995
Parsing the effects of nitric oxide, S-nitrosothiols, and peroxynitrite on inducible nitric oxide synthase-dependent cardiac myocyte apoptosisQ73111100
Induction of nitric oxide production by natural killer cells: its role in tumor cell deathQ73114746
Induction of apoptosis by S-nitrosoglutathione and Cu2+ or Ni2+ ion through modulation of bax, bad, and bcl-2 proteins in human colon adenocarcinoma cellsQ73177498
Apoptotic cell death induced by taxol is inhibited by nitric oxide in human leukemia HL-60 cellsQ73233653
Ethanol-induced neutrophil apoptosis is mediated through nitric oxideQ73310432
Nitric oxide production and Fas surface expression mediate two independent pathways of cytokine-induced murine beta-cell damageQ73313395
Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutaseQ73316561
Activated macrophages direct apoptosis and suppress mitosis of mesangial cellsQ73407093
Cu,Zn-superoxide dismutase-dependent apoptosis induced by nitric oxide in neuronal cellsQ73441794
Role of nitric oxide and peroxynitrite in bile salt-induced apoptosis: relevance to colon carcinogenesisQ73489101
Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawalQ73503948
Apoptosis induction by nitric oxide in adult cardiomyocytes via cGMP-signaling and its impairment after simulated ischemiaQ73573634
Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytesQ73573637
The anti-death league: associative control of apoptosis in developing retinal tissueQ73635175
Cellular non-heme iron content is a determinant of nitric oxide-mediated apoptosis, necrosis, and caspase inhibitionQ73643152
Nitric oxide production and mitochondrial dysfunction during rat thymocyte apoptosisQ73699260
Cyclic nucleotides suppress tumor necrosis factor alpha-mediated apoptosis by inhibiting caspase activation and cytochrome c release in primary hepatocytes via a mechanism independent of Akt activationQ73704166
Concentration-dependent effects of nitric oxide on mitochondrial permeability transition and cytochrome c releaseQ73737861
Caspase activation and cytochrome c release during HL-60 cell apoptosis induced by a nitric oxide donorQ73752047
Nitrite generation and antioxidant effects during neutrophil apoptosisQ73764545
Expression of inducible nitric oxide synthase and interleukin-12 in experimental necrotizing enterocolitisQ73918754
FK409, a spontaneous nitric oxide releaser, attenuates allograft vasculopathy in a rat aortic transplant modelQ73964064
Nitric oxide synthase activity in mitochondriaQ74038500
Negative feedback regulation of activated macrophages via Fas-mediated apoptosisQ74061176
Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemiaQ74088499
U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activationQ74147117
Nitric oxide donor-induced apoptosis in smooth muscle cells is modulated by protein kinase C and protein kinase AQ74213121
Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosisQ74462850
Nitric oxide fully protects against UVA-induced apoptosis in tight correlation with Bcl-2 up-regulationQ74485109
Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family proteaseQ74518169
Nitric oxide induces apoptotic death of cardiomyocytes via a cyclic-GMP-dependent pathwayQ74520555
Nitric oxide donors induce stress signaling via ceramide formation in rat renal mesangial cellsQ74583650
Nitric oxide-induced S-glutathionylation and inactivation of glyceraldehyde-3-phosphate dehydrogenaseQ74638106
Nitric oxide induces and inhibits apoptosis through different pathwaysQ77304349
Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxideQ77313286
Nitric oxide stimulates chronic ceramide formation in glomerular endothelial cellsQ77381133
Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activationQ77394071
Nitric oxide suppression of apoptosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c releaseQ77545246
Bcl-2 prevents caspase-independent cell deathQ77677956
Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathwaysQ77840747
Nitric-oxide production by murine mammary adenocarcinoma cells promotes tumor-cell invasivenessQ77853467
Elevation of inducible nitric oxide synthase activity in human endometrium during menstruationQ77897399
Effects of nitric oxide on the eosinophil survival in vitro. A role for nitrosyl-hemeQ77937483
Mass spectrometric analysis of nitric oxide-modified caspase-3Q78010420
Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signalingQ78094837
Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosisQ78171893
P433issue8
P921main subjectapoptotic processQ14599311
P304page(s)1421-1441
P577publication date2001-08-01
P1433published inInternational ImmunopharmacologyQ15751306
P1476titleThe regulatory role of nitric oxide in apoptosis
P478volume1

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