Susceptibility to seizure-induced excitotoxic cell death is regulated by an epistatic interaction between Chr 18 (Sicd1) and Chr 15 (Sicd2) loci in mice

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Susceptibility to seizure-induced excitotoxic cell death is regulated by an epistatic interaction between Chr 18 (Sicd1) and Chr 15 (Sicd2) loci in mice is …
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scholarly articleQ13442814

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P819ADS bibcode2014PLoSO...9k0515S
P356DOI10.1371/JOURNAL.PONE.0110515
P932PMC publication ID4198259
P698PubMed publication ID25333963
P5875ResearchGate publication ID267273150

P2093author name stringPaula Elyse Schauwecker
P2860cites workRecurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsyQ28141298
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Differential susceptibility to seizures induced by systemic kainic acid treatment in mature DBA/2J and C57BL/6J miceQ71889266
Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate modelQ72101989
Rat strain and age differences in kainic acid induced seizuresQ72237357
Kainic acid neurotoxicity toward hippocampal formation: dependence on specific excitatory pathwaysQ72858547
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Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strainsQ80796346
The competitive NMDA receptor antagonist CGP 40116 protects against status epilepticus-induced neuronal damageQ34322496
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neuronsQ34394699
Congenic strains provide evidence that a mapped locus on chromosome 15 influences excitotoxic cell deathQ34420451
Human epilepsies: interaction of genetic and acquired factorsQ34537195
New insights from the use of pilocarpine and kainate models.Q34768815
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Kainic acid induced seizures: neurochemical and histopathological changesQ42447130
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Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependentQ44530084
Mouse strain differences in kainic acid sensitivity, seizure behavior, mortality, and hippocampal pathologyQ44654020
Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysisQ44998269
Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strainsQ45303517
Pilocarpine vs. lithium-pilocarpine for induction of status epilepticus in mice: development of spontaneous seizures, behavioral alterations and neuronal damageQ45730102
Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background.Q45944012
Differences in sensitivity to the convulsant pilocarpine in substrains and sublines of C57BL/6 mice.Q45984455
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Hippocampal neuron damage in human epilepsy: Meyer's hypothesis revisitedQ46261486
A quantitative trait locus on chromosome 18 is a critical determinant of excitotoxic cell death susceptibilityQ46481869
Fine mapping of a seizure susceptibility locus on mouse Chromosome 1: nomination of Kcnj10 as a causative geneQ47688826
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cellsQ48211649
Genetic influences on electrical seizure thresholdQ48345135
Neuronal stress and injury in C57/BL mice after systemic kainic acid administrationQ48351353
Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strainsQ48383242
Neuronal, dendritic, and vascular profiles of human temporal lobe epilepsy correlated with cellular physiology in vivo.Q48401779
Limbic seizures induced by systemically applied kainic acid: how much kainic acid reaches the brain?Q48420719
Epistasis: too often neglected in complex trait studies?Q48541812
Maturation of kainic acid seizure-brain damage syndrome in the rat. II. Histopathological sequelaeQ48592651
Kainic acid seizure syndrome and binding sites in developing rats.Q48663251
Electroconvulsive thresholds of inbred mouse strainsQ48836931
25 Use of excitatory amino acids to make axon-sparing lesions of hypothalamusQ48849942
Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell deathQ49116308
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
excitotoxicityQ901117
P304page(s)e110515
P577publication date2014-10-15
P1433published inPLOS OneQ564954
P1476titleSusceptibility to seizure-induced excitotoxic cell death is regulated by an epistatic interaction between Chr 18 (Sicd1) and Chr 15 (Sicd2) loci in mice
P478volume9

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cites work (P2860)
Q42293508A Standardized Protocol for Stereotaxic Intrahippocampal Administration of Kainic Acid Combined with Electroencephalographic Seizure Monitoring in Mice
Q48477939Distinct behavioral and epileptic phenotype differences in 129/P mice compared to C57BL/6 mice subject to intraamygdala kainic acid-induced status epilepticus
Q37597272Everolimus is better than rapamycin in attenuating neuroinflammation in kainic acid-induced seizures
Q42292646Repeated low-dose kainate administration in C57BL/6J mice produces temporal lobe epilepsy pathology but infrequent spontaneous seizures.

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