Nanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapy

scientific article

Nanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/NN102187V
P932PMC publication ID2991391
P698PubMed publication ID20958072
P5875ResearchGate publication ID47498816

P50authorZhihang ChenQ57273751
P2093author name stringMarie-France Penet
Zaver M Bhujwalla
Cong Li
Paul T Winnard
Dmitri Artemov
Tomoyo Takagi
Flonné Wildes
P2860cites workDifferential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatmentQ24317541
The structure of Escherichia coli cytosine deaminaseQ27637502
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansQ27860867
Side-effects of a systemic injection of linear polyethylenimine-DNA complexesQ28192320
5-Fluorouracil: mechanisms of action and clinical strategiesQ28201937
Structures of O-linked oligosaccharides present in the proteoglycans secreted by human mammary epithelial cellsQ70134324
Isolation and characterization of proteoglycans secreted by normal and malignant human mammary epithelial cellsQ70280900
Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancersQ28217662
Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cellsQ28259789
Mechanisms of gene silencing by double-stranded RNAQ28282560
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimineQ29616154
Studies of human tumors by MRS: a reviewQ30833628
The use of 19F spectroscopy and diffusion-weighted MRI to evaluate differences in gene-dependent enzyme prodrug therapiesQ30973716
Tumour phospholipid metabolismQ33179622
In vivo molecular imaging for planning radiation therapy of gliomas: an application of 1H MRSI.Q33184714
Frequency and cost of chemotherapy-related serious adverse effects in a population sample of women with breast cancerQ33372268
Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancerQ33881902
Applications of molecular MRI and optical imaging in cancerQ33986159
Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategyQ34135239
Strategies for enzyme/prodrug cancer therapy.Q34436759
Imaging of cationic multifunctional liposome-mediated delivery of COX-2 siRNA.Q34640040
RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapyQ34759878
Clinical utility of proton magnetic resonance spectroscopy in characterizing breast lesionsQ34790978
Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminaseQ35693935
From bench to bedside for gene-directed enzyme prodrug therapy of cancerQ36061340
Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalizationQ36178042
siRNA-based approaches in cancer therapyQ36373107
Novel gene-directed enzyme prodrug therapies against prostate cancerQ36543076
Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions.Q36607242
Choline metabolism in cancer: implications for diagnosis and therapyQ36670926
Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines.Q36900208
Gadolinium-enhanced magnetic resonance imaging, renal failure and nephrogenic systemic fibrosis/nephrogenic fibrosing dermopathyQ37160825
Transport of molecules in the tumor interstitium: a reviewQ39768023
Conjugation of poly-L-lysine to bacterial cytosine deaminase improves the efficacy of enzyme/prodrug cancer therapyQ39976413
Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancerQ39981076
In vivo imaging of siRNA delivery and silencing in tumorsQ40166593
Multimodal image-guided enzyme/prodrug cancer therapyQ40206021
RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferationQ40344986
Choline kinase inhibition induces the increase in ceramides resulting in a highly specific and selective cytotoxic antitumoral strategy as a potential mechanism of action.Q40513977
Malignant transformation alters membrane choline phospholipid metabolism of human mammary epithelial cellsQ40979828
Production of sulfated proteoglycans by human breast cancer cell lines: binding to fibroblast growth factor-2.Q41120686
Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery systemQ42812609
Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.Q42833424
Fluoropyrimidine chemotherapy in a rat model: comparison of fluorouracil metabolite profiles determined by high-field 19F-NMR spectroscopy of tissues ex vivo with therapy response and toxicity for locoregional vs systemic infusion protocolsQ44891522
Image-guided enzyme/prodrug cancer therapyQ46788931
Dissemination of Information on Potentially Fatal Adverse Drug Reactions for Cancer Drugs From 2000 to 2002: First Results From the Research on Adverse Drug Events and Reports ProjectQ60148401
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)6707-6716
P577publication date2010-10-19
P1433published inACS NanoQ2819067
P1476titleNanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapy
P478volume4

Reverse relations

cites work (P2860)
Q39161466A biodegradable polymersome containing Bcl-xL siRNA and doxorubicin as a dual delivery vehicle for a synergistic anticancer effect.
Q47106820Acid-degradable Dextran as an Image Guided siRNA Carrier for COX-2 Downregulation.
Q35537301Adenoviral-mediated imaging of gene transfer using a somatostatin receptor-cytosine deaminase fusion protein
Q35112040Choline metabolism in malignant transformation
Q37636194Degradable Dextran Nanopolymer as a Carrier for Choline Kinase (ChoK) siRNA Cancer Therapy
Q38657755Genetically encoded iron-associated proteins as MRI reporters for molecular and cellular imaging
Q35312455High-field small animal magnetic resonance oncology studies.
Q38710046Imaging-guided delivery of RNAi for anticancer treatment
Q37974175In vivo imaging of the systemic delivery of small interfering RNA.
Q36949372MR - eyes for cancer: looking within an impenetrable disease
Q30354223Magnetic Nanoparticle Facilitated Drug Delivery for Cancer Therapy with Targeted and Image-Guided Approaches
Q38982546Magnetic Resonance Imaging and Spectroscopy in Cancer Theranostic Imaging
Q36910668Magnetic Resonance Spectroscopy of siRNA-Based Cancer Therapy
Q35064453Molecular and functional imaging of invasion and metastasis: windows into the metastatic cascade
Q30367515Molecular imaging of the tumor microenvironment for precision medicine and theranostics.
Q38112726Multimodality imaging of RNA interference
Q38383478Nanomedicine for gene therapy.
Q91928770Natural Polysaccharides for siRNA Delivery: Nanocarriers Based on Chitosan, Hyaluronic Acid, and Their Derivatives
Q38814327Oligonucleotide-based theranostic nanoparticles in cancer therapy
Q38808957PSMA-specific theranostic nanoplex for combination of TRAIL gene and 5-FC prodrug therapy of prostate cancer.
Q33791366PSMA-targeted theranostic nanoplex for prostate cancer therapy.
Q40262447Prodrug enzymes and their applications in image-guided therapy of cancer: tracking prodrug enzymes to minimize collateral damage
Q28255877Progress toward in vivo use of siRNAs-II
Q35618915Recent advances in nonviral vectors for gene delivery
Q35625854Superparamagnetic iron oxide nanoparticles: promises for diagnosis and treatment of cancer.
Q39084885Targeting Phospholipid Metabolism in Cancer
Q88502315Theranostics and metabolotheranostics for precision medicine in oncology
Q49207200Therapeutic effects of adenovirus-mediated CD and NIS expression combined with Na131I/5-FC on human thyroid cancer
Q38191832Tumor-targeting multifunctional nanoparticles for siRNA delivery: recent advances in cancer therapy

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