Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers

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Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/DDDT.S65678
P932PMC publication ID4199987
P698PubMed publication ID25336915

P50authorJoo-Youn ChoQ86428159
P2093author name stringSang-Heon Cho
Tae-Eun Kim
Kyoung Soo Lim
Kyung-Sang Yu
Seo Hyun Yoon
Namyi Gu
In-Jin Jang
Mi Young Bahng
Min Kyu Park
P2860cites workStandards of medical care in diabetes--2013Q29620309
Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefitsQ33602360
Incorporating Incretin-Based Therapies Into Clinical Practice: Differences Between Glucagon-Like Peptide 1 Receptor Agonists and Dipeptidyl Peptidase 4 InhibitorsQ34374336
Therapeutic potential of dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetesQ34648201
Diurnal pattern to insulin secretion and insulin action in healthy individualsQ36339611
The incretin system and its role in type 2 diabetes mellitusQ37266863
Pharmacokinetics of dipeptidylpeptidase-4 inhibitorsQ37768821
DPP-4 inhibitors: what may be the clinical differentiators?Q37779906
Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences.Q37910902
Incretin effect: GLP-1, GIP, DPP4.Q37921901
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Dipeptidylpeptidase-4 (DPP-4) inhibitors are favourable to glucagon-like peptide-1 (GLP-1) receptor agonists: yes.Q37979374
Clinical pharmacokinetics and pharmacodynamics of vildagliptinQ37984567
Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human studyQ38464759
Pharmacokinetic study of saxagliptin in healthy Chinese subjectsQ38470357
Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storageQ40035788
Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.Q40667988
Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men.Q42164402
A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesisQ42480141
A diabetes report card for the United States: quality of care in the 1990sQ43960347
Diurnal variation in glucose tolerance. Cyclic suppression of insulin action and insulin secretion in normal-weight, but not obese, subjectsQ44686546
Diurnal variation in blood sugar and serum insulin in response to glucose and/or glucagon in healthy subjectsQ51671377
DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes.Q51764065
The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesityQ58448710
Circadian modulation of glucose and insulin responses to meals: relationship to cortisol rhythmQ68098718
[GLP-1 (7-36) amide [GLIP-glucagon like insulinotropic peptide] as a potential treatment for NIDDM]Q77416575
Discovery of DA-1229: a potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetesQ84097974
The incretin effect and secretion in obese and lean women with polycystic ovary syndrome: a pilot studyQ84357802
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
pharmacodynamicsQ725307
P304page(s)1709-1721
P577publication date2014-10-06
P1433published inDrug Design, Development and TherapyQ2566724
P1476titleMultiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers
P478volume8

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cites work (P2860)
Q38644587Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.
Q38922177DPP-4 inhibitors in diabetic complications: role of DPP-4 beyond glucose control
Q38625769Effects of clarithromycin on the pharmacokinetics of evogliptin in healthy volunteers
Q51373715Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel dipeptidyl peptidase-4 inhibitor, evogliptin (DA-1229).
Q33626226Efficacy and safety of adding evogliptin versus sitagliptin for metformin-treated patients with type 2 diabetes: A 24-week randomized, controlled trial with open label extension
Q92341046Efficacy and safety of evogliptin in the treatment of type 2 diabetes mellitus in a Brazilian population: a randomized bridging study
Q47185104Efficacy and safety of evogliptin monotherapy in patients with type 2 diabetes and moderately elevated glycated haemoglobin levels after diet and exercise
Q34500716Evogliptin: First Global Approval
Q38828606Evogliptin: a new dipeptidyl peptidase inhibitor for the treatment of type 2 diabetes
Q53236559In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations.
Q37179450Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects.
Q36808160Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects
Q91795502Possibility of pharmacokinetic drug interaction between a DPP-4 inhibitor and a SGLT2 inhibitor

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