Apolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes

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Apolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes is …
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scholarly articleQ13442814

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P356DOI10.2337/DB10-0844
P932PMC publication ID2992786
P698PubMed publication ID20826564
P5875ResearchGate publication ID46181049

P50authorCecilia MorgantiniQ80166497
P2093author name stringSrinivasa T Reddy
Alan M Fogelman
Mohamad Navab
Satoshi Imaizumi
Victor Grijalva
P2860cites workPreparation of lipid hydroperoxide-free low-density lipoproteinsQ77907804
A liquid chromatography/mass spectrometric method for simultaneous analysis of arachidonic acid and its endogenous eicosanoid metabolites prostaglandins, dihydroxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and epoxyeicosatrienoic acids inQ79381692
Atherosclerosis: basic mechanisms. Oxidation, inflammation, and geneticsQ28300402
Lipid peroxidation in diabetes mellitusQ34384380
L-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in miceQ34566942
Lipids and lipoproteins in patients with type 2 diabetesQ35783120
Anatomical differences and atherosclerosis in apolipoprotein E-deficient mice with 129/SvEv and C57BL/6 genetic backgroundsQ36296729
Quantitative assessment of atherosclerotic lesions in miceQ36456167
Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosisQ36591939
Lipid peroxidation and decomposition--conflicting roles in plaque vulnerability and stabilityQ36725904
The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese miceQ37222394
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesionsQ37486465
ABCG1 mediated oxidized LDL-derived oxysterol efflux from macrophagesQ39778176
Role of oxidized low density lipoprotein in atherogenesisQ40343074
Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproductsQ41009444
Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1.Q41759686
Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3.Q41759689
Anti-inflammatory apoA-I-mimetic peptides bind oxidized lipids with much higher affinity than human apoA-I.Q41829964
Binding characteristics of scavenger receptors on liver endothelial and Kupffer cells for modified low-density lipoproteinsQ42830218
Studies with apolipoprotein A-II transgenic mice indicate a role for HDLs in adiposity and insulin resistanceQ43541268
Oral administration of an Apo A-I mimetic Peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterolQ43862770
Enhanced lipid peroxidation and platelet activation in the early phase of type 1 diabetes mellitus: role of interleukin-6 and disease duration.Q44480697
Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic ratsQ44495010
Risk factors for coronary heart disease in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications StudyQ44745070
Irbesartan but not amlodipine suppresses diabetes-associated atherosclerosisQ44801373
Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice.Q46030815
Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic miceQ46212386
LDL- is a lipid hydroperoxide-enriched circulating lipoprotein.Q46430533
D-4F and statins synergize to render HDL antiinflammatory in mice and monkeys and cause lesion regression in old apolipoprotein E-null miceQ46450296
D-4F induces heme oxygenase-1 and extracellular superoxide dismutase, decreases endothelial cell sloughing, and improves vascular reactivity in rat model of diabetesQ46531373
Involvement of preexisting lipid hydroperoxides in Cu(2+)-stimulated oxidation of low-density lipoprotein.Q54189438
Long-Term Treatment with the Apolipoprotein A1 Mimetic Peptide Increases Antioxidants and Vascular Repair in Type I Diabetic RatsQ60684945
Scavenger Receptor BI Mediates the Selective Uptake of Oxidized Cholesterol Esters by Rat LiverQ63359539
In VivoRegulation of Scavenger Receptor BI and the Selective Uptake of High Density Lipoprotein Cholesteryl Esters in Rat Liver Parenchymal and Kupffer CellsQ63359542
The F2-isoprostane, 8-epi-prostaglandin F2 alpha, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonistQ67584372
Lipid hydroperoxide involvement in copper-dependent and independent oxidation of low density lipoproteinsQ70120377
Oxidized lipids in atherogenesis: formation, destruction and actionQ73447357
Imaging of aortic atherosclerotic lesions by (125)I-LDL, (125)I-oxidized-LDL, (125)I-HDL and (125)I-BSAQ74083217
Oxidative stress and coronary artery diseaseQ77129618
Epidemiology of Diabetes Interventions and Complications (EDIC). Design, implementation, and preliminary results of a long-term follow-up of the Diabetes Control and Complications Trial cohortQ77764997
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
murine modelQ122890741
P304page(s)3223-3228
P577publication date2010-09-08
P1433published inDiabetesQ895262
P1476titleApolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes
P478volume59

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cites work (P2860)
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