scholarly article | Q13442814 |
P819 | ADS bibcode | 2012PLoSO...742034M |
P356 | DOI | 10.1371/JOURNAL.PONE.0042034 |
P932 | PMC publication ID | 3411609 |
P698 | PubMed publication ID | 22870278 |
P5875 | ResearchGate publication ID | 230624539 |
P2093 | author name string | Steven J Berberich | |
Benjamin Bates | |||
Jillian Fraser | |||
Michael P Markey | |||
Nicholas Wyatt | |||
Pooja Mandke | |||
P2860 | cites work | hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase | Q24291829 |
MdmX is a substrate for the deubiquitinating enzyme USP2a | Q24336863 | ||
Identification of an aberrantly spliced form of HDMX in human tumors: a new mechanism for HDM2 stabilization | Q40355383 | ||
DNA damage-induced MDMX degradation is mediated by MDM2. | Q40636352 | ||
Clinical implications of the p53 tumor-suppressor gene | Q40865658 | ||
Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential | Q41451986 | ||
Inactivation of the p53 pathway in retinoblastoma. | Q42152329 | ||
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites | Q42419115 | ||
Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2. | Q44521310 | ||
p53 is activated in response to disruption of the pre-mRNA splicing machinery. | Q44950735 | ||
A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network | Q46721077 | ||
Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target | Q48031061 | ||
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest | Q48078984 | ||
Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. | Q48789680 | ||
Significance of HDMX-S (or MDM4) mRNA splice variant overexpression and HDMX gene amplification on primary soft tissue sarcoma prognosis. | Q54662769 | ||
Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification. | Q55476278 | ||
[HDMX amplification and high levels of HDMX-S splice variant are correlated with a poor prognosis in soft tissue sarcomas] | Q80067621 | ||
DNA damage induces MDMX nuclear translocation by p53-dependent and -independent mechanisms | Q24540261 | ||
Formation, regulation and evolution of Caenorhabditis elegans 3'UTRs | Q24598773 | ||
MicroRNA targeting specificity in mammals: determinants beyond seed pairing | Q24607724 | ||
A map of human genome variation from population-scale sequencing | Q24617794 | ||
miR-148 targets human DNMT3b protein coding region | Q24642540 | ||
The microRNA.org resource: targets and expression | Q24650094 | ||
Clustal W and Clustal X version 2.0 | Q27860517 | ||
Prediction of plant microRNA targets | Q28219387 | ||
The miR-34 family in cancer and apoptosis | Q28245865 | ||
Tumour suppression: disruption of HAUSP gene stabilizes p53 | Q28254102 | ||
A microRNA component of the p53 tumour suppressor network | Q28305330 | ||
Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling | Q28477912 | ||
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis | Q29547575 | ||
A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development | Q29618436 | ||
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis | Q29619556 | ||
Validation of MdmX as a therapeutic target for reactivating p53 in tumors | Q34209099 | ||
MiR-34, SIRT1 and p53: the feedback loop | Q34946471 | ||
MDM2 promotes ubiquitination and degradation of MDMX | Q35161842 | ||
A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites | Q35582977 | ||
Regulation of MDMX expression by mitogenic signaling | Q36498007 | ||
Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity | Q36732343 | ||
The guardian's little helper: microRNAs in the p53 tumor suppressor network | Q37023130 | ||
Mitochondrial MDM4 (MDMX): an unpredicted role in the p53-mediated intrinsic apoptotic pathway | Q37627089 | ||
Regulation of MDM4. | Q37825197 | ||
The impact of miRNA target sites in coding sequences and in 3'UTRs | Q38336299 | ||
A critical role for noncoding 5S rRNA in regulating Mdmx stability | Q39472408 | ||
miR-10a overexpression is associated with NPM1 mutations and MDM4 downregulation in intermediate-risk acute myeloid leukemia | Q39501936 | ||
MicroRNAs regulate human hepatocyte nuclear factor 4alpha, modulating the expression of metabolic enzymes and cell cycle. | Q39538948 | ||
An illegitimate microRNA target site within the 3' UTR of MDM4 affects ovarian cancer progression and chemosensitivity | Q39630646 | ||
HDMX-L is expressed from a functional p53-responsive promoter in the first intron of the HDMX gene and participates in an autoregulatory feedback loop to control p53 activity. | Q39675744 | ||
Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2. | Q39853212 | ||
Full-length hdmX transcripts decrease following genotoxic stress | Q39949523 | ||
Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest | Q39992760 | ||
p53-mediated activation of miRNA34 candidate tumor-suppressor genes. | Q40102003 | ||
Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4. | Q40224078 | ||
MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin. | Q40244145 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | microRNA | Q310899 |
P304 | page(s) | e42034 | |
P577 | publication date | 2012-08-01 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | MicroRNA-34a modulates MDM4 expression via a target site in the open reading frame | |
P478 | volume | 7 |