Acid-induced pain and its modulation in humans.

scientific article

Acid-induced pain and its modulation in humans. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.2619-04.2004
P932PMC publication ID6730214
P698PubMed publication ID15574747

P50authorStephen B. McMahonQ29653464
Peter A McNaughtonQ38327746
Rebeccah SlaterQ56863311
P2093author name stringNicholas G Jones
Herve Cadiou
P2860cites workA new member of acid-sensing ion channels from pituitary glandQ22254230
Cloning and expression of a novel human brain Na+ channelQ24309379
The capsaicin receptor: a heat-activated ion channel in the pain pathwayQ24322558
A proton-gated cation channel involved in acid-sensingQ24329227
Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous systemQ24530236
Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neuronsQ24544425
Amiloride-blockable acid-sensing ion channels are leading acid sensors expressed in human nociceptorsQ24551151
Nonsteroid anti-inflammatory drugs inhibit both the activity and the inflammation-induced expression of acid-sensing ion channels in nociceptorsQ28189783
A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cellsQ28572405
A sensory neuron-specific, proton-gated ion channelQ28581453
Molecular cloning of a non-inactivating proton-gated Na+ channel specific for sensory neuronsQ28582678
The cloned capsaicin receptor integrates multiple pain-producing stimuliQ29547511
H(+)-gated cation channelsQ30579548
ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia.Q30873083
Causes and consequences of tumour acidity and implications for treatmentQ33818730
Proinflammatory mediators, stimulators of sensory neuron excitability via the expression of acid-sensing ion channels.Q34165309
Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.Q34711250
Molecular mechanisms of analgesia induced by opioids and ethanol: is the GIRK channel one of the keys?Q34922365
Potentiation of ATP-responses at a recombinant P2x2 receptor by neurotransmitters and related substancesQ35025413
Extended pharmacological profiles of rat P2Y2 and rat P2Y4 receptors and their sensitivity to extracellular H+ and Zn2+ ionsQ35045909
Topical acetylsalicylic, salicylic acid and indomethacin suppress pain from experimental tissue acidosis in human skinQ39472143
Sustained graded pain and hyperalgesia from harmless experimental tissue acidosis in human skinQ39493670
How Nerve Growth Factor Drives Physiological and Inflammatory Expressions of Acid-sensing Ion Channel 3 in Sensory NeuronsQ42450977
Pain due to experimental acidosis in human skin: evidence for non-adapting nociceptor excitationQ42515013
Molecular determinants for activation of G-protein-coupled inward rectifier K+ (GIRK) channels by extracellular acidosisQ42684810
DRASIC contributes to pH-gated currents in large dorsal root ganglion sensory neurons by forming heteromultimeric channelsQ44010634
Inhibition of G-protein-coupled inward rectifying K+ channels by intracellular acidosisQ44261811
Neurogenic hyperalgesia: psychophysical studies of underlying mechanismsQ45020805
An acid sensing ion channel (ASIC) localizes to small primary afferent neurons in ratsQ46152819
pH Dependency and desensitization kinetics of heterologously expressed combinations of acid-sensing ion channel subunitsQ47289083
Different sensitivities to pH of ATP-induced currents at four cloned P2X receptorsQ48614632
Mechanism of diclofenac analgesia: direct blockade of inflammatory sensitization.Q50775766
Pain due to tissue acidosis: a mechanism for inflammatory and ischemic myalgia?Q60678474
Receptor for protons in the membrane of sensory neuronsQ72893832
Why it hurts: researchers seek mechanisms of cancer painQ73472144
Role of protons in activation of cardiac sympathetic C-fibre afferents during ischaemia in catsQ78040234
P433issue48
P407language of work or nameEnglishQ1860
P304page(s)10974-10979
P577publication date2004-12-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleAcid-induced pain and its modulation in humans
P478volume24

Reverse relations

cites work (P2860)
Q89004730A Review of Chronic Musculoskeletal Pain: Central and Peripheral Effects of Diclofenac
Q36015313ASIC3 channels in multimodal sensory perception
Q34471261ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain
Q36978173ASIC3, a sensor of acidic and primary inflammatory pain
Q24815639ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons
Q27013569ASICs as therapeutic targets for migraine
Q37717831Abnormal cardiac autonomic regulation in mice lacking ASIC3.
Q28588134Acid sensing ion channels in dorsal spinal cord neurons
Q41181641Acid sensitivity of the spinal dorsal root ganglia C-fiber nociceptors innervating the guinea pig esophagus
Q28478617Acid solution is a suitable medium for introducing QX-314 into nociceptors through TRPV1 channels to produce sensory-specific analgesic effects
Q33664281Acid-Sensing Ion Channels and Pain
Q42941036Acid-Sensing Ion Channels as Potential Therapeutic Targets in Neurodegeneration and Neuroinflammation.
Q47910421Acid-induced experimental knee pain and hyperalgesia in healthy humans
Q49923333Acid-induced experimental muscle pain and hyperalgesia with single and repeated infusion in human forearm
Q36893109Acid-sensing ion channel 3 (ASIC3) cell surface expression is modulated by PSD-95 within lipid rafts
Q34703337Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases.
Q34049519Acid-sensing ion channels (ASICs): therapeutic targets for neurological diseases and their regulation
Q37626609Acid-sensing ion channels 3: a potential therapeutic target for pain treatment in arthritis
Q38170044Acid-sensing ion channels contribute to neurotoxicity.
Q26829975Acid-sensing ion channels in pain and disease.
Q36790381Acid-sensing ion channels in sensory perception.
Q30461048Acid-sensing ion channels: A new target for pain and CNS diseases
Q35178189Acid-sensitive ion channels and receptors
Q43197439An acid-sensing ion channel from shark (Squalus acanthias) mediates transient and sustained responses to protons
Q34569637Antinociception produced by Thalassia testudinum extract BM-21 is mediated by the inhibition of acid sensing ionic channels by the phenolic compound thalassiolin B.
Q84653157Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers
Q33747254Avian magnetite-based magnetoreception: a physiologist's perspective
Q64082975Basics on the use of acid-sensing ion channels' inhibitors as therapeutics
Q44940323Black mamba venom peptides target acid-sensing ion channels to abolish pain
Q38175134Calcium-permeable ion channels in pain signaling
Q34429295Cannabinoids inhibit acid-sensing ion channel currents in rat dorsal root ganglion neurons
Q34110895Capsaicin receptors are colocalized with sweet/bitter receptors in the taste sensing cells of circumvallate papillae
Q82028674Chapter 4 Primary hyperalgesia and nociceptor sensitization
Q58162894Chapter 8 Acid Sensing Ionic Channels
Q37332773Chemosensitivity and mechanosensitivity of nociceptors from incised rat hindpaw skin
Q51056084Current perspectives on acid-sensing ion channels: new advances and therapeutic implications.
Q37054860Cyclophosphamide-induced cystitis reduces ASIC channel but enhances TRPV1 receptor function in rat bladder sensory neurons
Q60691600Distinct ASIC currents are expressed in rat putative nociceptors and are modulated by nerve injury
Q21136396Do decapod crustaceans have nociceptors for extreme pH?
Q35900722ENaCs and ASICs as therapeutic targets
Q39647860Effect of a temperature increase in the non-noxious range on proton-evoked ASIC and TRPV1 activity
Q46721255Effect of amiloride on experimental acid-induced heartburn in non-erosive reflux disease
Q87868569Effects of creatine supplementation on nociception in young male and female mice
Q90210582Evolution of acid nociception: ion channels and receptors for detecting acid
Q46155875Extracellular pH and neuronal depolarization serve as dynamic switches to rapidly mobilize trkA to the membrane of adult sensory neurons.
Q48218153Extracellular protons enable activation of the calcium-dependent chloride channel TMEM16A.
Q43904721Facilitated neurotrophin release in sensitized human skin
Q90152219High Expression of Acid-Sensing Ion Channel 2 (ASIC2) in Bone Cells in Osteoporotic Vertebral Fractures
Q36167656Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions
Q64069586Hydrophobic Amines and Their Guanidine Analogues Modulate Activation and Desensitization of ASIC3
Q38060825Ibuprofen: from invention to an OTC therapeutic mainstay
Q34438987Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant
Q48143196Increased hyperpolarized [1-13 C] lactate production in a model of joint inflammation is not accompanied by tissue acidosis as assessed using hyperpolarized 13 C-labelled bicarbonate
Q90614329Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms
Q36309477Inhibition of acid sensing ion channel by ligustrazine on angina model in rat
Q48310094Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.
Q38040134Insights into the effects of diclofenac and other non-steroidal anti-inflammatory agents on ion channels
Q89505846Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin
Q38493496Intra-oral pre-treatment with capsaicin increases consumption of sweet solutions in rats
Q48890576Intracellular acidification evoked by moderate extracellular acidosis attenuates transient receptor potential V1 (TRPV1) channel activity in rat dorsal root ganglion neurons.
Q36122117Intracellular proton-mediated activation of TRPV3 channels accounts for the exfoliation effect of α-hydroxyl acids on keratinocytes.
Q39202461Lactate is a potent inhibitor of the capsaicin receptor TRPV1.
Q46646121Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons
Q46876531Modulation of acid-sensing ion channel activity by nitric oxide
Q37967696Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potential
Q34586100Molecular mechanisms underlying the analgesic property of intrathecal dexmedetomidine and its neurotoxicity evaluation: an in vivo and in vitro experimental study
Q51739932NS383 Selectively Inhibits Acid-Sensing Ion Channels Containing 1a and 3 Subunits to Reverse Inflammatory and Neuropathic Hyperalgesia in Rats.
Q37428800Nociceptors: a phylogenetic view
Q37947690Optimizing the early phase development of new analgesics by human pain biomarkers
Q33746858Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin, V1A receptor in primary sensory neurons
Q47114262PPAR-α acutely inhibits functional activity of ASICs in rat dorsal root ganglion neurons
Q38823502Pain transduction: a pharmacologic perspective
Q39337685Potentiation of acid-sensing ion channels by sulfhydryl compounds.
Q38668522Preclinical Assessment of Inflammatory Pain
Q36146292Prokineticin 2 potentiates acid-sensing ion channel activity in rat dorsal root ganglion neurons
Q41770049Properties of acid-induced currents in mouse dorsal root ganglia neurons
Q37331670Proton inhibition of unitary currents of vanilloid receptors
Q28573444Regulation of sensory neuron-specific acid-sensing ion channel 3 by the adaptor protein Na+/H+ exchanger regulatory factor-1
Q47795281Repeated oral administration of capsaicin increases anxiety-like behaviours with prolonged stress-response in rats
Q92758175Role of TRPV1 and TRPA1 Ion Channels in Inflammatory Bowel Diseases: Potential Therapeutic Targets?
Q93002690Selective Effects of Temperature on the Sensory Irritation but not Taste of NaCl and Citric Acid
Q21090192Selective inflammatory pain insensitivity in the African naked mole-rat (Heterocephalus glaber)
Q36334054Selective targeting of ASIC3 using artificial miRNAs inhibits primary and secondary hyperalgesia after muscle inflammation
Q59800790Sensing acidosis: nociception or sngception?
Q34620046Spider peptide toxins as leads for drug development
Q34883018Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels.
Q36365139Spinal antinociceptive action of amiloride and its interaction with tizanidine in the rat formalin test
Q38309100Structural domains underlying the activation of acid-sensing ion channel 2a.
Q37850687Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a.
Q36012306Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567
Q89467945The beta-adrenergic receptor agonist, terbutaline, reduces UVB-induced mechanical sensitization in humans
Q38859500The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.
Q54663264The interaction between NGF-induced hyperalgesia and acid-provoked pain in the infrapatellar fat pad and tibialis anterior muscle of healthy volunteers.
Q41917505The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.
Q46150516The molecular basis of acid insensitivity in the African naked mole-rat
Q38136600The pain of tendinopathy: physiological or pathophysiological?
Q34347350The pharmacology and therapeutic potential of small molecule inhibitors of acid-sensing ion channels in stroke intervention
Q24544187The receptor site of the spider toxin PcTx1 on the proton-gated cation channel ASIC1a
Q51794095Upregulation of acid-sensing ion channel ASIC1a in spinal dorsal horn neurons contributes to inflammatory pain hypersensitivity.
Q51989752[Mechanisms in the development of pain. Key issue in the periphery].
Q37170692pH-evoked dural afferent signaling is mediated by ASIC3 and is sensitized by mast cell mediators

Search more.