PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease

scientific article published on August 6, 2010

PPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1182/BLOOD-2010-02-272005
P953full work available at URLhttp://www.bloodjournal.org/cgi/content/abstract/116/22/4512
https://europepmc.org/articles/pmc2996113
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20693431/?tool=EBI
https://doi.org/10.1182/blood-2010-02-272005
https://europepmc.org/articles/PMC2996113
http://ashpublications.org/blood/article-pdf/116/22/4512/1496552/zh804810004512.pdf
P932PMC publication ID2996113
P698PubMed publication ID20693431
P5875ResearchGate publication ID45538040

P2093author name stringPeter M. Henson
R. William Vandivier
Ruby Fernandez-Boyanapalli
Donna L. Bratton
David W. H. Riches
S. Courtney Frasch
P2860cites workAdvances in treatment for chronic granulomatous diseaseQ45880406
Molecular circuits of resolution: formation and actions of resolvins and protectinsQ46391207
Abnormal apoptosis in chronic granulomatous disease and autoantibody production characteristic of lupusQ46774498
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.Q46815296
Deletion of PPAR gamma in alveolar macrophages is associated with a Th-1 pulmonary inflammatory responseQ47976088
PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.Q54439080
Apoptotic cells induce a phosphatidylserine-dependent homeostatic response from phagocytes.Q54571000
Leukotriene production and inactivation by normal, chronic granulomatous disease and myeloperoxidase-deficient neutrophilsQ70175878
Apoptotic cells, through transforming growth factor-beta, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophagesQ79287661
Mphi1 and Mphi2 can be re-polarized by Th2 or Th1 cytokines, respectively, and respond to exogenous danger signalsQ80141341
Chronic granulomatous diseaseQ84018615
ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophagesQ24683025
Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide productionQ28114945
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammationQ28344659
The p47phox mouse knock-out model of chronic granulomatous diseaseQ28504676
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenaseQ28587071
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytesQ29547633
Alternative activation of macrophages: an immunologic functional perspectiveQ29614353
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistanceQ29614354
Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophagesQ29616355
Genetic, biochemical, and clinical features of chronic granulomatous disease.Q30168989
Complement-dependent clearance of apoptotic cells by human macrophagesQ30442812
Clinical aspects of chronic granulomatous diseaseQ31804597
Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanismsQ33304942
Granulocyte apoptosis and its role in the resolution and control of lung inflammationQ33771415
Lupus erythematosus tumidus and chronic discoid lupus erythematosus in carriers of X-linked chronic granulomatous disease.Q33868203
A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivoQ33912964
Phagocytosis and clearance of apoptotic cells is mediated by MER.Q33946282
The phosphatidylserine receptor: a crucial molecular switch?Q34325344
Stimulatory Effects of Peroxisome Proliferator-Activated Receptor-gamma on Fcgamma Receptor-Mediated Phagocytosis by Alveolar MacrophagesQ36417564
PPARs and other nuclear receptors in inflammationQ36507833
Abnormal regulation of inflammatory skin responses in male patients with chronic granulomatous diseaseQ36622217
PPARs and molecular mechanisms of transrepressionQ36791361
Clearance of apoptotic cells by phagocytesQ36850155
NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2AQ36981038
Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4Q37116947
Nonresolving inflammation in gp91phox-/- mice, a model of human chronic granulomatous disease, has lower adenosine and cyclic adenosine 5'-monophosphateQ37215898
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathwaysQ38316513
Involvement of a functional NADPH oxidase in neutrophils and macrophages during programmed cell clearance: implications for chronic granulomatous diseaseQ39830520
Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophilsQ40591748
Resolution-phase macrophages possess a unique inflammatory phenotype that is controlled by cAMP.Q41782419
Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteasesQ43612862
Gene correction reduces cutaneous inflammation and granuloma formation in murine X-linked chronic granulomatous disease.Q43900123
PPARgamma promotes mannose receptor gene expression in murine macrophages and contributes to the induction of this receptor by IL-13.Q43974270
Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.Q43982575
IL-13 attenuates gastrointestinal candidiasis in normal and immunodeficient RAG-2(-/-) mice via peroxisome proliferator-activated receptor-gamma activationQ44133828
Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammationQ44164532
Diminished production of anti-inflammatory mediators during neutrophil apoptosis and macrophage phagocytosis in chronic granulomatous disease (CGD).Q44417195
Antiinflammatory Roles of Peroxisome Proliferator–activated Receptor γ in Human Alveolar MacrophagesQ44620791
The peroxisome proliferator-activated receptor gamma ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiencyQ45285892
P4510describes a project that usesImageJQ1659584
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
chronic granulomatous diseaseQ2165663
P304page(s)4512-4522
P577publication date2010-08-06
P1433published inBloodQ885070
P1476titlePPARγ activation normalizes resolution of acute sterile inflammation in murine chronic granulomatous disease
P478volume116

Reverse relations

cites work (P2860)
Q5872634415d-PGJ-loaded nanocapsules ameliorate experimental gout arthritis by reducing pain and inflammation in a PPAR-gamma-sensitive manner in mice
Q39016299An Update on the Use of Immunomodulators in Primary Immunodeficiencies
Q36797270An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD
Q26825935Apoptotic cell clearance: basic biology and therapeutic potential.
Q55385710Chronic Granulomatous Disease: Epidemiology, Pathophysiology, and Genetic Basis of Disease.
Q35098193Chronic granulomatous disease: overview and hematopoietic stem cell transplantation
Q35745685Corticosteroid therapy for liver abscess in chronic granulomatous disease
Q35131029Current concepts of hyperinflammation in chronic granulomatous disease
Q26864795Emerging roles for lysophosphatidylserine in resolution of inflammation
Q38042926Emerging roles of eosinophils and eosinophil-derived lipid mediators in the resolution of inflammation
Q28260398Ex vivo and in vitro effect of serum amyloid a in the induction of macrophage M2 markers and efferocytosis of apoptotic neutrophils
Q59361040Future of Care for Patients With Chronic Granulomatous Disease: Gene Therapy and Targeted Molecular Medicine
Q89266985Galectin-3 in M2 Macrophages Plays a Protective Role in Resolution of Neuropathology in Brain Parasitic Infection by Regulating Neutrophil Turnover
Q38046124Hanging in the balance: endogenous anti-inflammatory mechanisms in tissue repair and fibrosis
Q33984427Impaired clearance of apoptotic cells in chronic inflammatory diseases: therapeutic implications
Q36269059Impaired efferocytosis in human chronic granulomatous disease is reversed by pioglitazone treatment
Q41755070Interstitial lung disease with multiple microgranulomas in chronic granulomatous disease
Q38363796Macrophage defense mechanisms against intracellular bacteria.
Q53604237Mer signaling increases the abundance of the transcription factor LXR to promote the resolution of acute sterile inflammation.
Q35927561Modulation of macrophage efferocytosis in inflammation
Q30538643Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice.
Q37441655Myeloid Cell Turnover and Clearance
Q54241856NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages.
Q36586166NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.
Q36382191NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis.
Q33911333NOX2-dependent regulation of inflammation
Q35151051Neutrophil clearance: when the party is over, clean-up begins
Q28282760Neutrophils regulate tissue Neutrophilia in inflammation via the oxidant-modified lipid lysophosphatidylserine
Q34307982Obesity impairs apoptotic cell clearance in asthma
Q26771755PPARγ and the Innate Immune System Mediate the Resolution of Inflammation
Q28070173PPARγ in Bacterial Infections: A Friend or Foe?
Q37089046Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution.
Q35090974Pioglitazone restores phagocyte mitochondrial oxidants and bactericidal capacity in chronic granulomatous disease.
Q90383809Recent advances in chronic granulomatous disease
Q52733597Role of gp91phox in hepatic macrophage programming and alcoholic liver disease.
Q28304843Signaling via macrophage G2A enhances efferocytosis of dying neutrophils by augmentation of Rac activity
Q36509966Systemic analysis of PPARγ in mouse macrophage populations reveals marked diversity in expression with critical roles in resolution of inflammation and airway immunity
Q34680660The Role of Efferocytosis in Atherosclerosis
Q38644234The role of mitochondrial ROS in antibacterial immunity.
Q36432359VIP treatment prevents embryo resorption by modulating efferocytosis and activation profile of maternal macrophages in the CBAxDBA resorption prone model

Search more.