scholarly article | Q13442814 |
P819 | ADS bibcode | 2010PNAS..10720251G |
P356 | DOI | 10.1073/PNAS.1009021107 |
P953 | full work available at URL | https://europepmc.org/articles/pmc2996644?pdf=render |
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21059932/?tool=EBI | ||
https://europepmc.org/articles/PMC2996644 | ||
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21059932/pdf/?tool=EBI | ||
https://europepmc.org/articles/PMC2996644?pdf=render | ||
https://doi.org/10.1073/pnas.1009021107 | ||
https://pnas.org/doi/pdf/10.1073/pnas.1009021107 | ||
P932 | PMC publication ID | 2996644 |
P698 | PubMed publication ID | 21059932 |
P5875 | ResearchGate publication ID | 47717880 |
P50 | author | Hermona Soreq | Q15989736 |
C Linn Cadieux | Q81456537 | ||
P2093 | author name string | Irene Cherni | |
Ian Puffenberger | |||
Jacquelyn Kilbourne | |||
Karli Kelley | |||
Latha Kannan | |||
Neil Robbins | |||
Pierre-Emmanuel Garnaud | |||
Douglas M. Cerasoli | |||
Shane A. Kasten | |||
Tamara C. Otto | |||
David E. Lenz | |||
Clarence A. Broomfield | |||
Tsafrir S. Mor | |||
Brian C. Geyer | |||
Sean M. Hodgins | |||
Zeke P. Oliver | |||
Tony E. Reeves | |||
Ryan R. Woods | |||
P2860 | cites work | Recombinant human butyrylcholinesterase from milk of transgenic animals to protect against organophosphate poisoning | Q24683895 |
Six peptide wound signals derived from a single precursor protein in Ipomoea batatas leaves activate the expression of the defense gene sporamin | Q28270058 | ||
Three hydroxyproline-rich glycopeptides derived from a single petunia polyprotein precursor activate defensin I, a pathogen defense response gene | Q28298770 | ||
Effect of chemical modification of recombinant human acetylcholinesterase by polyethylene glycol on its circulatory longevity | Q28344427 | ||
Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior | Q28393492 | ||
Lessons to be learnt from organophosphorus pesticide poisoning for the treatment of nerve agent poisoning | Q30230225 | ||
Hierarchy of post-translational modifications involved in the circulatory longevity of glycoproteins. Demonstration of concerted contributions of glycan sialylation and subunit assembly to the pharmacokinetic behavior of bovine acetylcholinesterase | Q30882412 | ||
Translational control of recombinant human acetylcholinesterase accumulation in plants | Q33286207 | ||
Glycoproteomic characterization of butyrylcholinesterase from human plasma | Q33315276 | ||
Molecular farming of pharmaceutical proteins | Q34114595 | ||
Protection conferred by recombinant Yersinia pestis antigens produced by a rapid and highly scalable plant expression system | Q34250117 | ||
The role of oximes in the treatment of nerve agent poisoning in civilian casualties | Q34575075 | ||
Self-assembly of the plant cell wall requires an extensin scaffold | Q34588080 | ||
Microbiological, biological, and chemical weapons of warfare and terrorism | Q34695957 | ||
The butyrylcholinesterase knockout mouse as a model for human butyrylcholinesterase deficiency | Q34721465 | ||
Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine. | Q34735257 | ||
Organophosphate induced delayed polyneuropathy | Q35137356 | ||
Clinical manifestations of sarin nerve gas exposure | Q35193776 | ||
Molecular biology of human serum cholinesterase | Q36463434 | ||
The acute treatment of nerve agent exposure | Q36582889 | ||
Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: a mini review | Q36692384 | ||
Natural products and their derivatives as cholinesterase inhibitors in the treatment of neurodegenerative disorders: an update | Q37160820 | ||
The butyrylcholinesterase K variant confers structurally derived risks for Alzheimer pathology | Q37285146 | ||
Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath | Q37398055 | ||
Controlled concealment of exposed clearance and immunogenic domains by site-specific polyethylene glycol attachment to acetylcholinesterase hypolysine mutants | Q40068841 | ||
Purification of transgenic plant-derived recombinant human acetylcholinesterase-R. | Q40355007 | ||
Comparative plasma proteome analysis of lymphoma-bearing SJL mice | Q40364333 | ||
Bioscavengers for the protection of humans against organophosphate toxicity | Q40372121 | ||
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ: differential expression in fast and slow twitch muscle fibers is driven by distinct promoters | Q40563952 | ||
Amino acid domains control the circulatory residence time of primate acetylcholinesterases in rhesus macaques (Macaca mulatta). | Q40623691 | ||
Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates. | Q41860506 | ||
High-level expression of functional recombinant human butyrylcholinesterase in silkworm larvae by Bac-to-Bac system | Q42021307 | ||
Expression of biologically active human butyrylcholinesterase in the cabbage looper (Trichoplusia ni). | Q42056595 | ||
Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase. | Q43114723 | ||
Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase | Q43600352 | ||
Characterization of butyrylcholinesterase antagonism of cocaine-induced hyperactivity | Q43999048 | ||
Wild-type and A328W mutant human butyrylcholinesterase tetramers expressed in Chinese hamster ovary cells have a 16-hour half-life in the circulation and protect mice from cocaine toxicity | Q44072269 | ||
Physostigmine and hyoscine improves protection against the lethal and incapacitating effects of nerve agent poisoning in the guinea-pig | Q44184701 | ||
Estimation of the Upper Limit of Human Butyrylcholinesterase Dose Required for Protection against Organophosphates Toxicity: a Mathematically Based Toxicokinetic Model | Q44644039 | ||
Novel inhibitors of acetyl- and butyrylcholinesterase derived from the alkaloids dehydroevodiamine and rutaecarpine | Q45278433 | ||
Butyrylcholinesterase inhibitory guaianolides from Amberboa ramosa. | Q46403388 | ||
Potency of several oximes to reactivate human acetylcholinesterase and butyrylcholinesterase inhibited by paraoxon in vitro | Q46490779 | ||
Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma | Q46742699 | ||
Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers | Q46853141 | ||
Cholinesterase inhibition by potato glycoalkaloids slows mivacurium metabolism. | Q51390273 | ||
Design and expression of organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase. | Q52321064 | ||
A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase. | Q52552251 | ||
Butyrylcholinesterase and acetylcholinesterase prophylaxis against soman poisoning in mice | Q56058104 | ||
Protein engineering of a human enzyme that hydrolyzes V and G nerve agents: design, construction and characterization | Q56058106 | ||
Comparison of antidote protection against soman by pyridostigmine, HI-6 and acetylcholinesterase | Q70602362 | ||
Trimerization domain of the collagen tail of acetylcholinesterase | Q73214277 | ||
Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase | Q74023875 | ||
Role of oligosaccharides in the pharmacokinetics of tissue-derived and genetically engineered cholinesterases | Q74095213 | ||
Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters | Q77333539 | ||
Comparison of polyethylene glycol-conjugated recombinant human acetylcholinesterase and serum human butyrylcholinesterase as bioscavengers of organophosphate compounds | Q79792445 | ||
Enzyme-kinetic investigation of different sarin analogues reacting with human acetylcholinesterase and butyrylcholinesterase | Q80099485 | ||
Host-regulated disposition of mammalian AChEs | Q81482933 | ||
P433 | issue | 47 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | identical protein binding | Q14762994 |
butyrylcholinesterase | Q22679015 | ||
P304 | page(s) | 20251-20256 | |
P577 | publication date | 2010-11-08 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents | |
P478 | volume | 107 |
Q30202947 | A highly stable minimally processed plant-derived recombinant acetylcholinesterase for nerve agent detection in adverse conditions |
Q97424799 | A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding |
Q36247635 | A rationally designed mutant of plasma platelet-activating factor acetylhydrolase hydrolyzes the organophosphorus nerve agent soman |
Q37718518 | Amino-acid mutations to extend the biological half-life of a therapeutically valuable mutant of human butyrylcholinesterase |
Q45071150 | Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development |
Q36287480 | Bacterial expression, correct membrane targeting and functional folding of the HIV-1 membrane protein Vpu using a periplasmic signal peptide |
Q42237480 | Chemical Polysialylation and In Vivo Tetramerization Improve Pharmacokinetic Characteristics of Recombinant Human Butyrylcholinesterase-Based Bioscavengers |
Q36567954 | Chemical polysialylation of human recombinant butyrylcholinesterase delivers a long-acting bioscavenger for nerve agents in vivo. |
Q39329265 | Cholinesterase reactivators and bioscavengers for pre- and post-exposure treatments of organophosphorus poisoning. |
Q42094010 | Creation of a protective pulmonary bioshield against inhaled organophosphates using an aerosolized bioscavenger |
Q35215813 | Development of organophosphate hydrolase activity in a bacterial homolog of human cholinesterase |
Q38152506 | Drug development for the management of organophosphorus poisoning. |
Q37684636 | Expression of human butyrylcholinesterase with an engineered glycosylation profile resembling the plasma-derived orthologue |
Q46598048 | Growth kinetics and scale-up of Agrobacterium tumefaciens. |
Q35243815 | His-tag truncated butyrylcholinesterase as a useful construct for in vitro characterization of wild-type and variant butyrylcholinesterases |
Q48297788 | Human butyrylcholinesterase efficacy against nerve agent exposure |
Q33757315 | Manufacturing economics of plant-made biologics: case studies in therapeutic and industrial enzymes |
Q36281887 | Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity |
Q34693466 | Oligomerization status influences subcellular deposition and glycosylation of recombinant butyrylcholinesterase in Nicotiana benthamiana |
Q37989116 | Organophosphorus hydrolase as an in vivo catalytic nerve agent bioscavenger |
Q36166979 | Plant expression of cocaine hydrolase-Fc fusion protein for treatment of cocaine abuse |
Q41620409 | Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity |
Q42216415 | Protection against paraoxon toxicity by an intravenous pretreatment with polyethylene-glycol-conjugated recombinant butyrylcholinesterase in macaques |
Q41287188 | Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques |
Q39171367 | Recombinant human butyrylcholinesterase as a new-age bioscavenger drug: development of the expression system |
Q34639611 | Reversal of succinylcholine induced apnea with an organophosphate scavenging recombinant butyrylcholinesterase |
Q53776548 | Synthesis and study on activity in vitro of the high purity human butyrylcholinesterase conjugated with gold nanoparticles. |
Q37009481 | Transient Expression of Tetrameric Recombinant Human Butyrylcholinesterase in Nicotiana benthamiana. |
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