Prognostic impact of hyaluronan and its regulators in pancreatic ductal adenocarcinoma

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Prognostic impact of hyaluronan and its regulators in pancreatic ductal adenocarcinoma is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...880765C
P356DOI10.1371/JOURNAL.PONE.0080765
P932PMC publication ID3823618
P698PubMed publication ID24244714
P5875ResearchGate publication ID258639754

P2093author name stringNorihiro Sato
Shiro Kohi
Koji Yamaguchi
Xiao-Bo Cheng
P2860cites workHYAL1 overexpression is correlated with the malignant behavior of human breast cancerQ24313097
HYAL1LUCA-1, a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNAQ28137780
The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locusQ28264764
Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinomaQ29616287
Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan contentQ33444259
HYAL-1 hyaluronidase: a potential prognostic indicator for progression to muscle invasion and recurrence in bladder cancerQ33688043
The six hyaluronidase-like genes in the human and mouse genomesQ34103842
Hyaluronan catabolism: a new metabolic pathwayQ34361766
Localisation of hyaluronate (HA) in primary tumors and nude mouse xenografts of human pancreatic carcinomas using a biotinylated HA-binding proteinQ71659979
Pancreatic carcinoma is characterized by elevated content of hyaluronan and chondroitin sulfate with altered disaccharide compositionQ73098910
Stromal and epithelial expression of tumor markers hyaluronic acid and HYAL1 hyaluronidase in prostate cancerQ73693135
Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancerQ74093456
Signaling properties of hyaluronan receptorsQ34444928
Association of hyaluronic acid family members (HAS1, HAS2, and HYAL‐1) with bladder cancer diagnosis and prognosisQ34512129
Mammalian hyaluronan synthasesQ35038976
Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survivalQ35745456
Molecular biomarkers: their increasing role in the diagnosis, characterization, and therapy guidance in pancreatic cancer.Q36464111
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancerQ36550798
Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rateQ36617504
Impact of the hyaluronan-rich tumor microenvironment on cancer initiation and progressionQ37194824
Stromal biology and therapy in pancreatic cancer.Q37802090
Hyaluronan in human malignanciesQ37816562
Tumor microenvironment and progression of pancreatic cancer.Q37852994
Tissue biomarkers for prognosis in pancreatic ductal adenocarcinoma: a systematic review and meta-analysisQ37858851
Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancerQ37885319
Diagnostic, prognostic, and predictive biomarkers in pancreatic cancerQ38021384
Evaluation of the prognostic potential of hyaluronic acid and hyaluronidase (HYAL1) for prostate cancerQ38452266
Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblastsQ40507994
Differential expression of the hyaluronan receptors CD44 and RHAMM in human pancreatic cancer cellsQ41169185
Hyaluronan is a secretory product of human pancreatic adenocarcinoma cells.Q42818827
High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancerQ43582728
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectpancreatic ductal carcinomaQ8263002
adenocarcinomaQ356033
P304page(s)e80765
P577publication date2013-11-11
P1433published inPLOS OneQ564954
P1476titlePrognostic impact of hyaluronan and its regulators in pancreatic ductal adenocarcinoma
P478volume8

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cites work (P2860)
Q509645103D-spheroids: What can they tell us about pancreatic ductal adenocarcinoma cell phenotype?
Q376067334-Methylumbelliferone Suppresses Hyaluronan Synthesis and Tumor Progression in SCID Mice Intra-abdominally Inoculated With Pancreatic Cancer Cells
Q549382914-Methylumbelliferone inhibits enhanced hyaluronan synthesis and cell migration in pancreatic cancer cells in response to tumor-stromal interactions.
Q38817997A novel epigenetic mechanism regulating hyaluronan production in pancreatic cancer cells
Q89972746A qualitative transcriptional prognostic signature for patients with stage I-II pancreatic ductal adenocarcinoma
Q42181013Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.
Q36152259Antitumor effects of the hyaluronan inhibitor 4-methylumbelliferone on pancreatic cancer
Q101120968Beyond just a tight fortress: contribution of stroma to epithelial-mesenchymal transition in pancreatic cancer
Q38199723Brief overview of selected approaches in targeting pancreatic adenocarcinoma
Q90140489CD44 splice variant (CD44v3) promotes progression of urothelial carcinoma of bladder through Akt/ERK/STAT3 pathways: novel therapeutic approach
Q91612583Clinical Trials Targeting the Stroma in Pancreatic Cancer: A Systematic Review and Meta-Analysis
Q47123105Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going
Q86521508Decreased hyaluronidase 1 expression is associated with early disease recurrence in human endometrial cancer
Q89596127Direct comparison of optical and electron microscopy methods for structural characterization of extracellular vesicles
Q40961838ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer.
Q35653691Emerging roles for hyaluronidase in cancer metastasis and therapy
Q89967768Extracellular Matrix in the Tumor Microenvironment and Its Impact on Cancer Therapy
Q26752391Hijacking the Hexosamine Biosynthetic Pathway to Promote EMT-Mediated Neoplastic Phenotypes
Q90681590Hyaluronan activated-metabolism phenotype (HAMP) in pancreatic ductal adenocarcinoma
Q39997796Hyaluronan stimulates pancreatic cancer cell motility
Q38930438Hyaluronic acid in digestive cancers
Q56890107Immune Checkpoint Inhibition for Pancreatic Ductal Adenocarcinoma: Current Limitations and Future Options
Q33764696Is hyaluronan deposition in the stroma of pancreatic ductal adenocarcinoma of prognostic significance?
Q38717187KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer
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Q93234403Novel prognostic markers within the CD44-stromal ligand network in pancreatic cancer
Q39453620Promising therapeutics of gastrointestinal cancers in clinical trials
Q38823693Receptor for Hyaluronic Acid-Mediated Motility is Associated with Poor Survival in Pancreatic Ductal Adenocarcinoma
Q26766075Role of hyaluronan in pancreatic cancer biology and therapy: Once again in the spotlight
Q92259502Stromal Features of the Primary Tumor Are Not Prognostic in Genetically Engineered Mice of Pancreatic Cancer
Q33827708Stromal reengineering to treat pancreas cancer
Q38260975Sugars in the microenvironment: the sticky problem of HA turnover in tumors
Q38856978Synergistic effect of targeting the epidermal growth factor receptor and hyaluronan synthesis in oesophageal squamous cell carcinoma cells.
Q26752400Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma
Q37729238The Development of a Novel Therapeutic Strategy to Target Hyaluronan in the Extracellular Matrix of Pancreatic Ductal Adenocarcinoma
Q64082778The material properties of naked mole-rat hyaluronan
Q89586019Why HALO 301 Failed and Implications for Treatment of Pancreatic Cancer

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