Interventional strategies against prion diseases

scientific article

Interventional strategies against prion diseases is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1033326084
P356DOI10.1038/35094590
P698PubMed publication ID11584312

P2093author name stringAguzzi A
Glatzel M
Heppner FL
Montrasio F
Prinz M
P2860cites workNeuro-immune connection in spread of prions in the body?Q57083714
The same prion strain causes vCJD and BSEQ57092996
Turning off follicular dendritic cellsQ59068710
Reversion of prion protein conformational changes by synthetic b-sheet breaker peptidesQ59691802
Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapieQ64447657
NGF modulates sympathetic innervation of lymphoid tissuesQ72037953
Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathiesQ74452125
Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulationQ24525199
Branched polyamines cure prion-infected neuroblastoma cellsQ24529092
Impaired prion replication in spleens of mice lacking functional follicular dendritic cellsQ28144723
Mice devoid of PrP are resistant to scrapieQ28249108
Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxinQ28507630
Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissueQ28586439
Distinct roles in lymphoid organogenesis for lymphotoxins alpha and beta revealed in lymphotoxin beta-deficient miceQ28587819
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's diseaseQ28588314
A route for prion neuroinvasion.Q30328574
Immunoaffinity purification and neutralization of scrapie prion infectivityQ33646402
Neuroinvasion by a Creutzfeldt-Jakob disease agent in the absence of B cells and follicular dendritic cellsQ33930758
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibodyQ33930771
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion diseaseQ33933969
Prions: health scare and biological challenge.Q34185897
Doxycycline control of prion protein transgene expression modulates prion disease in miceQ36527236
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodiesQ36663046
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous systemQ36688984
Sleepless in Bologna: transmission of fatal familial insomniaQ41052801
Methods of sympathetic degeneration and alterationQ41364932
Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob diseaseQ41652295
Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organsQ42196937
Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant stateQ42675291
Prion (PrPSc)-specific epitope defined by a monoclonal antibodyQ42816365
Between cows and monkeysQ43213308
Normal development and behaviour of mice lacking the neuronal cell-surface PrP proteinQ43522858
Sympathetic innervation of lymphoreticular organs is rate limiting for prion neuroinvasionQ43702721
Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agentQ44592404
A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain geneQ46098688
Antibodies inhibit prion propagation and clear cell cultures of prion infectivityQ46161882
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissuesQ47713235
Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters.Q48263573
Prion research: the next frontiersQ48540005
A crucial role for B cells in neuroinvasive scrapie.Q48574532
Effectiveness of anthracycline against experimental prion disease in Syrian hamstersQ48706421
Complement facilitates early prion pathogenesisQ48930440
Normal host prion protein necessary for scrapie-induced neurotoxicityQ49160879
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.Q54014234
Porphyrin and phthalocyanine antiscrapie compounds.Q54061556
Potent inhibition of scrapie-associated PrP accumulation by congo redQ54131452
Transepithelial prion transport by M cellsQ57083694
PrP expression in B lymphocytes is not required for prion neuroinvasionQ57083708
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectprion protein familyQ24724413
P304page(s)745-749
P577publication date2001-10-01
P1433published inNature Reviews NeuroscienceQ2108225
P1476titleInterventional strategies against prion diseases
P478volume2

Reverse relations

cites work (P2860)
Q27641839A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme
Q45140134Amyloid aggregates of the prion peptide PrP106-126 are destabilised by oxidation and by the action of dendrimers
Q35877214Antiprion immunotherapy: to suppress or to stimulate?
Q36579822Antiprion prophylaxis by gene transfer of a soluble prion antagonist
Q38579674Biochemical aspects of dementias
Q35548991CNS pathogenesis of prion diseases
Q48959703Decrease in pathology and progression of scrapie after immunisation with synthetic prion protein peptides in hamsters.
Q35892062Diagnosing prion diseases: needs, challenges and hopes
Q27300832Effective gene therapy in a mouse model of prion diseases
Q30979178Effects of beta-sheet breaker peptide polymers on scrapie-infected mouse neuroblastoma cells and their affinities to prion protein fragment PrP(81-145).
Q64129780Elevated Levels of Tau Protein in Cerebrospinal Fluid of Patients With Probable Creutzfeldt-Jakob Disease
Q47365495Human prion diseases: epidemiology and integrated risk assessment
Q37569845Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection.
Q57083689Immunity against prions?
Q36436176Inhibition of PrP(Sc) formation in scrapie infected N2a cells by 5,7,8-trimethyl-3,4-dihydro-2H-1,4-benzoxazine derivatives.
Q40066046Intracellular accumulation of a mild-denatured monomer of the human PrP fragment 90-231, as possible mechanism of its neurotoxic effects
Q44544140Isolation of drugs active against mammalian prions using a yeast-based screening assay
Q24673105Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice
Q80373607Multiple antigenic peptides facilitate generation of anti-prion antibodies
Q33843281Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies
Q57083661Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
Q35622996Prions and the immune system: a journey through gut, spleen, and nerves
Q35714147Proteomic consequences of expression and pathological conversion of the prion protein in inducible neuroblastoma N2a cells
Q40201448RNAi: a novel strategy for the treatment of prion diseases
Q35990277Rational targeting for prion therapeutics.
Q36626116Searching for anti-prion compounds: cell-based high-throughput in vitro assays and animal testing strategies
Q48343268Soluble dimeric prion protein binds PrP(Sc) in vivo and antagonizes prion disease
Q80820095Testing for prions: a novel protocol for vCJD prevalence studies
Q33649832The prepared tau exon-specific antibodies revealed distinct profiles of tau in CSF of the patients with Creutzfeldt-Jakob disease
Q24549130Transmissible Spongiform Encephalopathies Affecting Humans
Q35038274Unfolding the role of protein misfolding in neurodegenerative diseases
Q34534616What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired?