AMPAkines have novel analgesic properties in rat models of persistent neuropathic and inflammatory pain

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AMPAkines have novel analgesic properties in rat models of persistent neuropathic and inflammatory pain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/ALN.0000000000000351
P932PMC publication ID4206834
P698PubMed publication ID25338127

P50authorJing WangQ60327500
P2093author name stringChen Su
Alexander M Le
Michelle Lee
Anthony Zou
P2860cites workGlutamatergic drugs for schizophrenia: a systematic review and meta-analysisQ22251177
Synaptic AMPA receptor plasticity and behavior.Q24607574
Descending control of nociception: Specificity, recruitment and plasticityQ24624664
Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disordersQ24632936
Periaqueductal gray neurons project to spinally projecting GABAergic neurons in the rostral ventromedial medullaQ24655339
Ampakines alleviate respiratory depression in ratsQ28263792
Glutamate-based therapeutic approaches: ampakinesQ28287452
AMPAKINE enhancement of social interaction in the BTBR mouse model of autismQ28388762
Quantitative assessment of tactile allodynia in the rat pawQ29617366
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonistsQ29618120
Animal models of neuropsychiatric disordersQ29619899
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin miceQ30486668
Cognitive impairment in pain through amygdala-driven prefrontal cortical deactivationQ33843541
Spared nerve injury: an animal model of persistent peripheral neuropathic painQ33912252
Effects of the putative cognitive-enhancing ampakine, CX717, on attention and object recognition memoryQ34029832
Incidence, Reversal, and Prevention of Opioid-induced Respiratory DepressionQ34088079
Mechanism and impact of allosteric AMPA receptor modulation by the ampakine CX546.Q34097927
Regulation of AMPA receptors during synaptic plasticityQ34155648
Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjectsQ34254887
Increasing deaths from opioid analgesics in the United StatesQ34550465
Brain-derived neurotrophic factor expression and respiratory function improve after ampakine treatment in a mouse model of Rett syndrome.Q34698021
Ampakine CX717 protects against fentanyl-induced respiratory depression and lethal apnea in rats.Q34982471
Selective antagonism of opioid-induced ventilatory depression by an ampakine molecule in humans without loss of opioid analgesiaQ35012514
A single subanesthetic dose of ketamine relieves depression-like behaviors induced by neuropathic pain in ratsQ35569752
Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depressionQ36129070
Reduced phosphorylation of the mTOR signaling pathway components in the amygdala of rats exposed to chronic stressQ36460302
Exacerbated mechanical allodynia in rats with depression-like behaviorQ36662841
Pharmacology of ampakine modulators: from AMPA receptors to synapses and behaviorQ36822516
Clinical aspects of depression in chronic pain patientsQ37038107
Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory painQ37067037
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neuronsQ37148281
Opioid complications and side effects.Q37149936
Calcium-permeable AMPA receptors in the nucleus accumbens regulate depression-like behaviors in the chronic neuropathic pain state.Q37345192
Presynaptic and postsynaptic amplifications of neuropathic pain in the anterior cingulate cortex.Q37352356
Central sensitization: a generator of pain hypersensitivity by central neural plasticityQ37361185
Modulation of agonist binding to AMPA receptors by 1-(1,4-benzodioxan-6-ylcarbonyl)piperidine (CX546): differential effects across brain regions and GluA1-4/transmembrane AMPA receptor regulatory protein combinationsQ37444397
In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesiaQ37484009
Glutamate-based antidepressants: 20 years on.Q37616806
Deconstructing the neuropathic pain phenotype to reveal neural mechanismsQ37988158
Pharmacovigilance: a review of opioid-induced respiratory depression in chronic pain patients.Q38091285
Involvement of excitatory amino acid receptors and nitric oxide in the rostral ventromedial medulla in modulating secondary hyperalgesia produced by mustard oil.Q39509604
Nucleus raphe magnus: a common mediator of opiate- and stimulus-produced analgesiaQ40081510
Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin CircuitryQ40093729
Evidence that an excitatory connection between the periaqueductal gray and nucleus raphe magnus mediates stimulation produced analgesiaQ40243992
Pain-induced analgesia mediated by mesolimbic reward circuitsQ41683720
Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex.Q42140596
The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory painQ42470459
Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex.Q42787094
Ampakine therapy to counter fentanyl-induced respiratory depressionQ43284708
Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammationQ43863049
The role of glutamate in opiate descending inhibition of nociceptive spinal reflexesQ43987241
Cold allodynia and hyperalgesia in neuropathic pain: the effect of N-methyl-D-aspartate (NMDA) receptor antagonist ketamine--a double-blind, cross-over comparison with alfentanil and placeboQ44313082
Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding.Q44345363
Inflammation-induced upregulation of AMPA receptor subunit expression in brain stem pain modulatory circuitryQ44509550
Role of excitatory amino acids in the generation and transmission of respiratory drive in neonatal rat.Q44625720
Psychological effects of a drug that facilitates brain AMPA receptors.Q44954505
Block of NMDA and non-NMDA receptor activation results in reduced background and evoked activity of central amygdala neurons in a model of arthritic painQ44994053
Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in ratsQ44994545
Coadministration of the AMPAKINE CX717 with propofol reduces respiratory depression and fatal apneasQ45245700
The contribution of TNF-α in the amygdala to anxiety in mice with persistent inflammatory painQ45331849
Ampakines and the threefold path to cognitive enhancementQ46042539
Effects of a memory-enhancing drug on DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor currents and synaptic transmission in hippocampusQ46180322
N-ethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammationQ46504263
Role of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunit GluR1 in spinal dorsal horn in inflammatory nociception and neuropathic nociception in rat.Q46741992
Generation and transmission of respiratory oscillations in medullary slices: role of excitatory amino acidsQ46913258
Hypofunction of glutamatergic neurotransmission in the periaqueductal gray contributes to nerve-injury-induced neuropathic painQ48011908
Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout miceQ48172014
Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal miceQ48195559
Reversal of monoarthritis-induced affective disorders by diclofenac in ratsQ48350144
Spinal monoamine and opiate systems partly mediate the antinociceptive effects produced by glutamate at brainstem sitesQ48602338
Food restriction enhances the central rewarding effect of abused drugs.Q48714187
Intra-accumbal NMDA but not AMPA/kainate receptor antagonist attenuates WIN55,212-2 cannabinoid receptor agonist-induced antinociception in the basolateral amygdala in a rat model of acute painQ48894625
Excitatory amino acid antagonists in the rostral ventromedial medulla inhibit mesencephalic morphine analgesia in ratsQ49083090
Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala of the rat.Q49124836
Experimental neuropathy in mice is associated with delayed behavioral changes related to anxiety and depression.Q50900176
Behavioural measures of depression and anxiety in rats with spinal nerve ligation-induced neuropathy.Q51090783
Comorbid chronic pain and depression: who is at risk?Q51642005
Glutamate-induced analgesia: blockade and potentiation by naloxoneQ71207759
The role of non-N-methyl-D-aspartate ionotropic glutamate receptors in the spinal transmission of nociception in normal animals and animals with carrageenan inflammationQ73029457
Intrathecal galanin alleviates allodynia-like behaviour in rats after partial peripheral nerve injuryQ74530592
AMPA receptors: a target for novel antidepressants?Q80601258
Assessment and analysis of mechanical allodynia-like behavior induced by spared nerve injury (SNI) in the mouseQ82856113
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectneuropathic painQ2798704
P304page(s)1080-1090
P577publication date2014-11-01
P1433published inAnesthesiologyQ2012635
P1476titleAMPAkines have novel analgesic properties in rat models of persistent neuropathic and inflammatory pain
P478volume121

Reverse relations

cites work (P2860)
Q64076165A novel neuromodulation strategy to enhance the prefrontal control to treat pain
Q88642284AMPA receptor positive allosteric modulators attenuate morphine tolerance and dependence
Q42990805AMPAkines Target the Nucleus Accumbens to Relieve Postoperative Pain
Q39152435AMPAkines and morphine provide complementary analgesia.
Q35236871Activation of corticostriatal circuitry relieves chronic neuropathic pain.
Q100525907Autism spectrum disorder-like behavior caused by reduced excitatory synaptic transmission in pyramidal neurons of mouse prefrontal cortex
Q26784030High Times for Painful Blues: The Endocannabinoid System in Pain-Depression Comorbidity
Q91599194Intracranial Pharmacotherapy and Pain Assays in Rodents
Q35165267Neuroplasticity underlying the comorbidity of pain and depression
Q49663721Novel analgesic effects of melanin-concentrating hormone on persistent neuropathic and inflammatory pain in mice
Q47639437Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency
Q47131724Reward Circuitry Plasticity in Pain Perception and Modulation
Q52563027Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.
Q64228428The Impact and Mechanism of a Novel Allosteric AMPA Receptor Modulator LCX001 on Protection Against Respiratory Depression in Rodents

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