Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production

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Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production is …
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scholarly articleQ13442814

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P819ADS bibcode2003PNAS..10015154V
P356DOI10.1073/PNAS.2433165100
P932PMC publication ID299932
P698PubMed publication ID14657387
P5875ResearchGate publication ID8975330

P50authorStephan BourQ55464748
P2093author name stringKlaus Strebel
Paul Spearman
Rita M Smith
Vasundhara Varthakavi
P2860cites workTsg101 and the vacuolar protein sorting pathway are essential for HIV-1 buddingQ24291784
Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retrovirusesQ24561846
Differential activities of the human immunodeficiency virus type 1-encoded Vpu protein are regulated by phosphorylation and occur in different cellular compartmentsQ24646897
The human immunodeficiency virus type 1 Vpu protein specifically binds to the cytoplasmic domain of CD4: implications for the mechanism of degradationQ24676509
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif proteinQ27860488
Cell type-dependence for Vpu functionQ28241247
A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motifQ28276184
Evidence for a newly discovered cellular anti-HIV-1 phenotypeQ28290967
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5Q28344177
SCH-C (SCH 351125), an orally bioavailable, small molecule antagonist of the chemokine receptor CCR5, is a potent inhibitor of HIV-1 infection in vitro and in vivoQ28362194
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineQ29547239
Identification of the regions of Fv1 necessary for murine leukemia virus restriction.Q33851839
Independent segregation of human immunodeficiency virus type 1 Gag protein complexes and lipid raftsQ34466295
Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytesQ35852056
The two biological activities of human immunodeficiency virus type 1 Vpu protein involve two separable structural domains.Q35854362
The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor?Q35854386
The pCL vector system: rapid production of helper-free, high-titer, recombinant retrovirusesQ35866801
The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses.Q35873115
Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAsQ36793376
The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and releaseQ36800610
Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu proteinQ36830393
Multiple copies of the Mason-Pfizer monkey virus constitutive RNA transport element lead to enhanced HIV-1 Gag expression in a context-dependent manner.Q38316167
Restriction of multiple divergent retroviruses by Lv1 and Ref1Q39056684
Complementation of murine cells for human immunodeficiency virus envelope/CD4-mediated fusion in human/murine heterokaryonsQ40066675
Generation of high-titer pseudotyped retroviral vectors with very broad host rangeQ40571115
Function of human immunodeficiency virus type 1 Vpu protein in various cell types.Q41277102
Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAsQ41686213
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression.Q43521980
Naturally occurring amino acid substitutions in the HIV-2 ROD envelope glycoprotein regulate its ability to augment viral particle release.Q44426365
p24 antigen capture assay for quantification of human immunodeficiency virus using readily available inexpensive reagentsQ45761377
Gag-Pol region determines the tropism of SIVagm for human cellsQ46612375
P433issue25
P407language of work or nameEnglishQ1860
P921main subjectHIVQ15787
P304page(s)15154-15159
P577publication date2003-12-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleViral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production
P478volume100