Endogenous fluorescence signatures in living pluripotent stem cells change with loss of potency

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Endogenous fluorescence signatures in living pluripotent stem cells change with loss of potency is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...743708S
P356DOI10.1371/JOURNAL.PONE.0043708
P932PMC publication ID3430704
P698PubMed publication ID22952742
P5875ResearchGate publication ID230805295

P50authorTimothy J. KampQ55135188
Kevin EliceiriQ28367456
P2093author name stringJayne M Squirrell
Avtar Roopra
Brenda M Ogle
Gary E Lyons
Nirupama K Shevde
Kassondra Meyer
Jimmy J Fong
Carlos A Ariza
Amber Mael
P2860cites workReproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregatesQ21144350
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Changing potency by spontaneous fusion.Q40740330
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Quantitative biomarkers of stem cell differentiation based on intrinsic two-photon excited fluorescenceQ47997281
Conformational dependence of intracellular NADH on metabolic state revealed by associated fluorescence anisotropyQ48906465
Dynamic changes in histone H3 phosphoacetylation during early embryonic stem cell differentiation are directly mediated by mitogen- and stress-activated protein kinase 1 via activation of MAPK pathways.Q50936672
Intrinsic fluorescence and redox changes associated with apoptosis of primary human epithelial cells.Q51085272
Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types.Q51139418
Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells.Q51902673
Cavitation of embryoid bodies requires optimal oxidative phosphorylation and AIF.Q52672756
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Changes in pyridine nucleotide levels alter oxygen consumption and extra-mitochondrial phosphates in isolated mitochondria: a 31P-NMR and NAD(P)H fluorescence studyQ69906120
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Respiratory enzymes in oxidative phosphorylation. VII. Binding of intramitochondrial reduced pyridine nucleotideQ78331114
A high glycolytic flux supports the proliferative potential of murine embryonic stem cellsQ79446699
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The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardiumQ29614435
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3Q29614624
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.Q30497916
Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoproteinQ30833030
High Throughput Screening with Multiphoton Excitation.Q30875227
Fluorescence lifetime imaging of unstained tissues: early results in human breast cancerQ30886062
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Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissuesQ33212339
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Multiphoton flow cytometry to assess intrinsic and extrinsic fluorescence in cellular aggregates: applications to stem cellsQ33649202
Multiphoton fluorescence lifetime imaging of 3D-stem cell spheroids during differentiationQ33779243
Low O2 tensions and the prevention of differentiation of hES cellsQ33932268
Energy metabolism in human pluripotent stem cells and their differentiated counterpartsQ33940583
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NAD+ metabolism in health and diseaseQ34001412
Multiplexed, high-throughput analysis of 3D microtissue suspensionsQ34014722
Detection of dead cells and measurement of cell killing by flow cytometryQ34032214
Label-free identification and characterization of human pluripotent stem cell-derived cardiomyocytes using second harmonic generation (SHG) microscopyQ34074507
Fluorescence lifetime measurements and biological imagingQ34076309
Multiphoton excitation provides optical sections from deeper within scattering specimens than confocal imagingQ34169170
Osteoblastic differentiation and stress response of human mesenchymal stem cells exposed to alternating current electric fieldsQ34576810
Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissueQ35170726
Dependence of mouse embryonic stem cells on threonine catabolismQ35216662
Differential binding of NAD+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensorQ35234301
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogrammingQ35656245
Label-free separation of human embryonic stem cells and their differentiating progenies by phasor fluorescence lifetime microscopyQ36052035
Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplantsQ36322764
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cellsQ36510839
Innate cellular fluorescence reflects alterations in cellular proliferationQ36858826
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectpluripotencyQ1894941
P304page(s)e43708
P577publication date2012-08-29
P1433published inPLOS OneQ564954
P1476titleEndogenous fluorescence signatures in living pluripotent stem cells change with loss of potency
P478volume7

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cites work (P2860)
Q38558038Advanced imaging approaches for regenerative medicine: Emerging technologies for monitoring stem cell fate in vitro and in vivo
Q61796182Autofluorescence is a Reliable in vitro Marker of Cellular Senescence in Human Mesenchymal Stromal Cells
Q57180667Autofluorescence lifetime imaging of cellular metabolism: Sensitivity toward cell density, pH, intracellular, and intercellular heterogeneity
Q38727617Comparative in vitro toxicity assessment of perfluorinated carboxylic acids
Q36123173Endogenous Optical Signals Reveal Changes of Elastin and Collagen Organization During Differentiation of Mouse Embryonic Stem Cells
Q34795900Fluorescence lifetime imaging of alterations to cellular metabolism by domain 2 of the hepatitis C virus core protein
Q39032866Noninvasive sorting of stem cell aggregates based on intrinsic markers
Q51193090Simple Monolayer Differentiation of Murine Cardiomyocytes via Nutrient Deprivation-Mediated Activation of β-Catenin.

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